[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100596503":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":21,"responsibleParty":34,"collaborators":10,"id":36,"slug":37,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":40,"acronym":10,"eligibilityCriteria":41,"healthyVolunteers":42,"sex":43,"minAge":44,"maxAge":45,"enrollmentInfo":46,"targetDuration":10,"studyType":49,"phases":10,"briefSummary":50,"conditions":51,"keywords":10,"overallStatus":54,"whyStopped":10,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":64},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Control",null,"30 control group matched as regards BMI, age and sex will be subjected to transthoracic echo and measuring serum endostatin level.",{"label":13,"type":10,"description":14,"interventionNames":10},"Cases of Psoriatic arthritis patients","30 PsA patients will be subjected to transthoracic echo, measuring serum endostatin level and modified composite psoriatic disease activity index",[16],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Dina Maamoun ElHadba, MSc Ain Shams University","CONTACT","01006780166","DinaElhadba@med.asu.edu",[22],{"facility":5,"status":10,"city":23,"state":24,"zip":25,"country":26,"countryCode":27,"cosmosGeoPoint":28,"geoPoint":33,"contacts":10},"Cairo","Abbassia","00202","Egypt","EG",{"type":29,"coordinates":30},"Point",[31,32],31.24967,30.06263,{"lat":32,"lon":31},{"type":35,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100596503","right-ventricular-strain-in-detecting-subclinical-right-ventricular-systolic-dysfunction-in-psoriatic-arthritis-patients-relation-to-serum-endostatin-level-100596503",false,"NCT07046312","Right Ventricular Strain in Detecting Subclinical Right Ventricular Systolic Dysfunction in Psoriatic Arthritis Patients: Relation to Serum Endostatin Level","Inclusion Criteria:\n\n* Psoriatic arthritis patients according to CASPAR criteria\n* Psoriatic arthritis patients without overt cardiovascular symptoms\n* Patients with age between 20 to 50 years of age\n\nExclusion Criteria:\n\n* Other systemic autoimmune diseases\n* Patients with a history of known valvular disease, atrial fibrillation or any other arrhythmia , heart failure, ischemic cardiomyopathy severe obstructive pulmonary diseases and metabolic syndrome.\n* Patients with medical disorders as renal, congenital heart diseases, hematological disorders and cancer patients.\n* Patients taking certain drugs that have been confirmed to be risk factors for PAH such as appetite suppressant intake drugs (aminorex, fenfluramine derivatives and benfluorex) and chemotherapeutic agents.\n* Family history of myocardial infarction, cerebrovascular disease or sudden death before the age of 65y in females and 55 y in males.",true,"ALL","20 Years","50 Years",{"count":47,"type":48},60,"ESTIMATED","OBSERVATIONAL","The aim is to assess early right ventricular systolic dysfunction in psoriatic arthritis patients using RV strain echocardiography",[52,53],"Psoriatic Arthritis (PsA)","Subclinical Right Ventricular Systolic Dysfunction","NOT_YET_RECRUITING","2025-06-29",{"date":57,"type":58},"2025-07-01","ACTUAL",{"date":60,"type":48},"2025-07",{"date":62,"type":48},"2027-04",{"name":5,"class":6},1]