[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100539003":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":18,"centralContacts":19,"locations":25,"responsibleParty":37,"collaborators":18,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":18,"eligibilityCriteria":47,"healthyVolunteers":43,"sex":48,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":18,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":18,"overallStatus":27,"whyStopped":18,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":69},{"fullName":5,"class":6},"Shaare Zedek Medical Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Risankizumab","EXPERIMENTAL","Induction regimen: 0,4,8 IV and then every 8 weeks sc",[13],"Drug: Risankizumab",[15],{"type":16,"name":9,"description":9,"armGroupLabels":17,"otherNames":18},"DRUG",[9],null,[20],{"name":21,"role":22,"phone":23,"phoneExt":18,"email":24},"Nataly Kawazba","CONTACT","97225645254","natalyk@szmc.org.il",[26],{"facility":5,"status":27,"city":28,"state":18,"zip":18,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":18},"RECRUITING","Jerusalem","Israel","IL",{"type":32,"coordinates":33},"Point",[34,35],35.21633,31.76904,{"lat":35,"lon":34},{"type":38,"investigatorFullName":39,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Prof. Amit Assa","Pediatric Gastroenterologist, Principal Investigator","100539003","risankizumab-in-children-with-crohns-disease-risakids-100539003",false,"NCT06298188","Risankizumab in Children With Crohn's Disease (RisaKids)","Risankizumab in Children With Crohn's Disease (RisaKids): A Multi-center PORTO Group Prospective Study","Inclusion Criteria:\n\n* Children under the age of 18 years,\n* Patients diagnosed with CD.\n* Patients commenced on risankizumab by treating physician (at least one dose), either alone or in combination with any other CD medications, at any stage of the disease.\n\nExclusion Criteria:\n\n\\* There will be no exclusion criteria to this study.","ALL","6 Years","18 Years",{"count":52,"type":53},90,"ESTIMATED","INTERVENTIONAL",[56],"NA","The goal of this observational study is to to prospectively explore the real life short (12 weeks) and longer term (54 weeks) clinical, biochemical and endoscopic outcomes of risankizumab in pediatric CD.\n\nThis is a 1-year prospective multi-center cohort study of children commencing on risankizumab for pediatric CD with 2 years extension for long-term follow-up. The investigators will record clinical manifestations, blood markers and fecal calprotectin, with monitoring for safety signals including infusion and injection site reactions, pyrexia and infections at various intervals as outlined below. The investigators will also include calprotectin monitoring and fecal sample collection for microbiome and serum samples for drug levels. According to available budget, the investigators will also collect fecal and serum samples for metabolome. Samples collection is optional, thus failure of bio-samples collection will not exclude patients from the study.",[59],"Crohn Disease","2024-11-27",{"date":62,"type":63},"2024-12-03","ACTUAL",{"date":65,"type":63},"2024-10-31",{"date":67,"type":53},"2026-10",{"name":5,"class":6},1]