[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595585":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":17,"locations":10,"responsibleParty":23,"collaborators":10,"id":27,"slug":28,"hasResults":29,"nctId":30,"briefTitle":31,"officialTitle":32,"acronym":10,"eligibilityCriteria":33,"healthyVolunteers":29,"sex":34,"minAge":35,"maxAge":10,"enrollmentInfo":36,"targetDuration":10,"studyType":39,"phases":10,"briefSummary":40,"conditions":41,"keywords":44,"overallStatus":48,"whyStopped":10,"lastUpdateSubmitDate":49,"lastUpdatePostDateStruct":50,"startDateStruct":53,"completionDateStruct":55,"leadSponsor":57,"locationsCount":10},{"fullName":5,"class":6},"Fudan University","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"NSCLC patients receiving standard treatment",null,[12],"Other: No intervention",[14],{"type":6,"name":15,"description":15,"armGroupLabels":16,"otherNames":10},"No intervention",[9],[18],{"name":19,"role":20,"phone":21,"phoneExt":10,"email":22},"Zhengfei Zhu, PhD","CONTACT","+8618017312901","fuscczzf@163.com",{"type":24,"investigatorFullName":25,"investigatorTitle":26,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Zhengfei Zhu","Professor","100595585","risk-and-prognosis-of-brain-metastasis-in-non-small-cell-lung-cancer-100595585",false,"NCT07034365","Risk and Prognosis of Brain Metastasis in Non-Small Cell Lung Cancer","Risk and Prognosis of Brain Metastasis in Non-Small Cell Lung Cancer: A Multicenter, Prospective, Observational Study","Inclusion Criteria:\n\n* Pathologically confirmed non-small cell lung cancer;\n* Age≥18 years old;\n* KPS score≥70;\n* Complete systemic imaging (including brain MRI) before treatment initiation, including contrast-enhanced MRI of the brain;\n* Receiving standard treatment;\n* Informed consent of the patient.\n\nExclusion Criteria:\n\n* Multiple primary or metastatic tumors (except early skin cancer, cervical carcinoma in situ that has been treated radically, with no recurrence or progression for more than 5 years);\n* Physical examination findings, clinical laboratory abnormalities, or other uncontrolled medical conditions identified by the investigator as potentially interfering with study results interpretation or increasing the patient's risk of - Uncontrolled epilepsy, central nervous system disease, or history of mental disorders, judged by the researcher to potentially interfere with the signing of the informed consent form or affect patient compliance;\n* Pregnant or lactating women.","ALL","18 Years",{"count":37,"type":38},2000,"ESTIMATED","OBSERVATIONAL","This multi-center, prospective, observational study aim to construct a comprehensive model, integrating common clinical pathological parameters, radiographic features and multi-omics data, for assessing the risk and prognosis of brain metastasis in NSCLC. This model is intended to address the following clinical needs: (1) Identify patients at high risk of brain metastasis; (2) Optimize the combined strategies of local and systemic treatments; (3) Predict the survival outcomes of patients with brain metastases from NSCLC and provide evidence-based support for individualized treatment decisions.",[42,43],"NSCLC (Non-small Cell Lung Cancer)","Brain Metastases From Non-small Cell Lung Cancer (NSCLC)",[45,46,47],"NSCLC","brain metastases","prognosis","NOT_YET_RECRUITING","2025-06-25",{"date":51,"type":52},"2025-06-29","ACTUAL",{"date":54,"type":38},"2025-08",{"date":56,"type":38},"2027-05",{"name":5,"class":6}]