[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100632154":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":12,"locations":7,"responsibleParty":18,"collaborators":7,"id":22,"slug":23,"hasResults":24,"nctId":25,"briefTitle":26,"officialTitle":27,"acronym":7,"eligibilityCriteria":28,"healthyVolunteers":24,"sex":29,"minAge":30,"maxAge":31,"enrollmentInfo":32,"targetDuration":30,"studyType":35,"phases":7,"briefSummary":36,"conditions":37,"keywords":7,"overallStatus":39,"whyStopped":7,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":7},{"fullName":5,"class":6},"Assiut University","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"Non-interventional assessment of growth and risk factors in thalassemic children","No therapeutic intervention is applied. The study involves only observational assessment of clinical history, anthropometric measurements, laboratory investigations, and growth parameters in thalassemic children. This distinguishes it from interventional studies.",[13],{"name":14,"role":15,"phone":16,"phoneExt":7,"email":17},"Aya Sale Sadek","CONTACT","+20 1555112872","assemaya8@gmail.com",{"type":19,"investigatorFullName":20,"investigatorTitle":21,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Aya Saleh Sadek","Resident of Pediatrics Faculty of Medicine, Assiut University","100632154","risk-factors-affecting-growth-in-thalassemic-children-at-auch-100632154",false,"NCT07509996","Risk Factors Affecting Growth in Thalassemic Children at AUCH","The Effect of Different Risk Factors on Growth Parameters of Thalassemic Patients in Assiut University Children Hospital","Inclusion Criteria:\n\n* Children aged 1 to 18 years diagnosed with β-thalassemia major based on hemoglobin electrophoresis or high-performance liquid chromatography (HPLC).\n* Receiving regular blood transfusions as part of standard management at AUCH.\n* Attending the hematology unit for at least one year prior to enrollment.\n\nExclusion Criteria:\n\n* • Children with other types of thalassemia.\n\n  * Presence of congenital diseases, chronic illnesses other than thalassemia (e.g., malignancy, tuberculosis, chronic hepatitis, congenital heart disease, chronic renal failure, epilepsy, diabetes mellitus), or primary endocrinopathies.\n  * Patients with other causes of short stature, such as hereditary bone dysplasia or systemic disorders.","ALL","12 Months","18 Years",{"count":33,"type":34},85,"ESTIMATED","OBSERVATIONAL","Thalassemia major is a hereditary hemoglobinopathy characterized by ineffective erythropoiesis and severe anemia, necessitating lifelong blood transfusions(1,2). Regular transfusions lead to iron overload, a primary driver of growth retardation in affected children. Iron accumulation in tissues like the pituitary and liver disrupts growth hormone secretion and insulin-like growth factor-1 production.",[38],"Thalassemia Majors (Beta-Thalassemia Major)","NOT_YET_RECRUITING","2026-03-28",{"date":42,"type":43},"2026-04-03","ACTUAL",{"date":45,"type":34},"2026-04-01",{"date":47,"type":34},"2027-05-01",{"name":5,"class":6}]