[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100472041":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":24,"locations":32,"responsibleParty":59,"collaborators":61,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":10,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":10,"studyType":76,"phases":10,"briefSummary":77,"conditions":78,"keywords":80,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Peking University Third Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"patients with pulmonary tuberculosis",null,"male patients aged 25-60 with active pulmonary tuberculosis",[13],"Other: no intervention",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"no intervention","no intervention; This study is a observational study. All patients received routine anti-tuberculosis regimen. Researchers will observe the clinical manifestation, pulmonary function and pulmonary CT manifestation within a few years after the cure of tuberculosis.",[9],[20],{"name":21,"affiliation":22,"role":23},"Yongchang Sun, MD","Respiratory and Critical Care Department, Peking University Third Hospital","STUDY_DIRECTOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Xiaoyan Gai, MD","CONTACT","13522708870","gxy81wfl79@163.com",{"name":31,"role":27,"phone":10,"phoneExt":10,"email":10},"Sun",[33,49],{"facility":5,"status":34,"city":35,"state":10,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"RECRUITING","Beijing","100191","China","CN",{"type":40,"coordinates":41},"Point",[42,43],116.39723,39.9075,{"lat":43,"lon":42},[46],{"name":47,"role":27,"phone":48,"phoneExt":10,"email":29},"Xiaoyan Gai, MD.","008613522708870",{"facility":50,"status":34,"city":35,"state":10,"zip":10,"country":37,"countryCode":38,"cosmosGeoPoint":51,"geoPoint":53,"contacts":54},"Beijing Geriatric Hospital",{"type":40,"coordinates":52},[42,43],{"lat":43,"lon":42},[55],{"name":56,"role":27,"phone":57,"phoneExt":10,"email":58},"Wenli Cao, MD","13161220446","yangqiang@tsinghua.org.cn",{"type":60,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[62],{"name":50,"class":6},"100472041","risk-factors-and-biomarkers-for-post-tuberculosis-lung-damage-100472041",false,"NCT05426720","Risk Factors and Biomarkers for Post-tuberculosis Lung Damage","Risk Factors and Biomarkers for Post-tuberculosis Lung Damage in a Chinese Cohort: Protocol for a Prospective Observational Study","Inclusion Criteria:\n\nMale patients aged 25-60 years newly diagnosed with active pulmonary TB.\n\nExclusion Criteria:\n\n1. patients with positive sputum smear or TB culture results;\n2. human immunodeficiency virus-positive patients;\n3. patients infected with multidrug-resistant TB;\n4. patients with malignant neoplasms (e.g., lung cancer) or severe cardiovascular and cerebrovascular diseases;\n5. non-compliant patients who were unable to complete the lung function tests;\n6. patients without lung parenchymal destruction (such as tuberculous pleurisy). -","MALE","25 Years","60 Years",{"count":74,"type":75},400,"ESTIMATED","OBSERVATIONAL","This prospective study aims to determine the incidence of Post-tuberculosis lung damage (PTLD), examine trends in the changes in lung function, and investigate the impact of smoking and other factors on respiratory symptoms, lung function, and chest CT findings, which will aid in the development of prognostic and therapeutic strategies for PTLD.",[79],"Pulmonary TB",[81,82],"post-tuberculosis lung damage","cigarette smoking","2022-06-16",{"date":85,"type":86},"2022-06-22","ACTUAL",{"date":88,"type":86},"2022-01-01",{"date":90,"type":75},"2027-12-31",{"name":5,"class":6},2]