[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631802":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":10,"locations":10,"responsibleParty":12,"collaborators":10,"id":16,"slug":17,"hasResults":18,"nctId":19,"briefTitle":20,"officialTitle":21,"acronym":10,"eligibilityCriteria":22,"healthyVolunteers":18,"sex":23,"minAge":24,"maxAge":25,"enrollmentInfo":26,"targetDuration":10,"studyType":29,"phases":10,"briefSummary":30,"conditions":31,"keywords":35,"overallStatus":42,"whyStopped":10,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":10},{"fullName":5,"class":6},"Assiut University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Hospitalized Children with Acute Bronchiolitis",null,"Children aged 1 to 24 months presenting to Assiut University Hospital with a confirmed clinical diagnosis of acute bronchiolitis per AAP 2014 criteria. This single cohort will be prospectively observed to identify and quantify risk factors associated with disease severity, including sociodemographic factors, feeding practices, and clinical assessments. Data collected will include hospitalization rates, ICU admissions, length of stay, and clinical management strategies such as oxygen therapy escalation and feeding support. As an observational study, no experimental interventions will be administered; patients will receive standard care.",{"type":13,"investigatorFullName":14,"investigatorTitle":15,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Mohammed Abdelregal Ahmed Mehanny","Resident at Pediatric Department, Assiut University","100631802","risk-factors-and-severity-of-bronchiolitis-in-hospitalized-children-at-assiut-university-hospital-100631802",false,"NCT07505420","Risk Factors and Severity of Bronchiolitis in Hospitalized Children at Assiut University Hospital","Clinical Epidemiology, Risk Factors Associated With Severity and Disease Burden of Bronchiolitis in Hospitalized Children in Assiut University Hospital","Inclusion Criteria:\n\n* Children aged 1-24 months presenting with acute bronchiolitis, defined per AAP 2014 criteria: preceding upper respiratory infection, wheezing, tachypnoea (\\>60 breaths\u002Fmin \\\u003C2 months, \\>50 \\\u003C12 months, \\>40 \\>12 months), and signs of respiratory distress (nasal flaring, grunting, retractions).\n* Confirmed clinical diagnosis by a pediatric pulmonologist.\n\nExclusion Criteria:\n\n* Known congenital heart disease, chronic lung disease (e.g., bronchopulmonary dysplasia), immunodeficiency, or neuromuscular disorders.\n* Recurrent wheezing suggesting asthma.\n* Gestational age \\\u003C32 weeks without recovery or birth weight \\\u003C1500g without catch-up growth.\n* Immunosuppression, recent (within 2 weeks) systemic steroids or antibiotics.","ALL","1 Month","24 Months",{"count":27,"type":28},65,"ESTIMATED","OBSERVATIONAL","The purpose of this observational study is to identify the risk factors that make bronchiolitis more severe in infants and toddlers. Bronchiolitis is a common viral lung infection that causes inflammation and airway obstruction, often leading to breathing difficulties and hospitalization in young children.\n\nResearchers will observe approximately 65 children, aged 1 to 24 months, who are admitted to Assiut University Hospital for acute bronchiolitis. Because this is an observational study, participants will receive standard medical care, and no experimental treatments will be tested.\n\nDuring the hospital stay, researchers will collect information through parent questionnaires and standard medical records. The research team will gather data on:\n\n* Family, social, and environmental factors, such as infant feeding practices, premature birth, and exposure to passive smoking.\n* The child's clinical symptoms and overall severity of illness upon arrival at the hospital.\n* Routine test results and the types of supportive care the child needs, such as extra oxygen or feeding assistance.\n* The total length of the hospital stay and whether the child requires intensive care (ICU) admission.\n\nBy identifying which factors are most closely linked to severe illness, the study aims to help doctors better predict the course of the disease early on, evaluate adherence to treatment guidelines, and ultimately reduce the health burden of bronchiolitis.",[32,33,34],"Bronchiolitis","Acute Bronchiolitis","Respiratory Syncytial Virus Infection",[32,33,36,37,38,39,40,41],"Respiratory Syncytial Virus Infections","Lower Respiratory Tract Infection","Respiratory Tract Infections","Viral Respiratory Infection","Wheezing","Respiratory Distress","NOT_YET_RECRUITING","2026-03-26",{"date":45,"type":46},"2026-04-01","ACTUAL",{"date":48,"type":28},"2026-05",{"date":50,"type":28},"2027-06",{"name":5,"class":6}]