[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100579796":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":10,"centralContacts":24,"locations":34,"responsibleParty":46,"collaborators":50,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":66,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":73,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Assiut University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"(1) Male or female patients é diagnosis of acute appendicitis.",null,"Patients who presented with complaints of right lower quadrant pain with symptoms and signs strongly suggestive of uncomplicated acute appendicitis that was confirmed on ultrasonography, were included. The modified Alvarado score and adult appendicitis score were calculated.",[13,14],"Drug: ceftriaxone","Drug: ceftriaxone 1 gm\u002F12 hourly and IV metronidazole 500 mg\u002F8 hourly",[16,21],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":10},"DRUG","ceftriaxone","ceftriaxone 1 gm\u002F12 hourly and IV metronidazole 500 mg\u002F8 hourly",[9],{"type":17,"name":19,"description":22,"armGroupLabels":23,"otherNames":10},"Conservative management",[9],[25,30],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Ahmed Mohammed Hussein Sayed Ahmed Razeen, MBBCh","CONTACT","+2001099414358","Ahmed.16266245@med.aun.edu.eg",{"name":31,"role":27,"phone":32,"phoneExt":10,"email":33},"Mohamed Taher Gamal Amin Taher, MBBCh &MD &PHD","+2001091289046","mohamedamin022@aun.edu.eg",[35],{"facility":5,"status":10,"city":36,"state":10,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":10},"Asyut","71515","Egypt","EG",{"type":41,"coordinates":42},"Point",[43,44],31.18368,27.18096,{"lat":44,"lon":43},{"type":47,"investigatorFullName":48,"investigatorTitle":49,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Ahmed Mohammed Hussein Sayed","Principal investigator",[51],{"name":5,"class":6},"100579796","risk-factors-of-failure-of-conservative-treatment-in-acute-non-complicated-appendicitis-100579796",false,"NCT06828952","Risk Factors of Failure of Conservative Treatment in Acute Non Complicated Appendicitis","appendicitis","Inclusion Criteria:\n\n* Male or female patients é diagnosis of acute appendicitis .\n* Patients with ages: from 16 to 60 years old.\n\nExclusion Criteria:\n\n* complicated AA (appendicolith, perforation, peri appendicular abscess or suspicion of a tumor).\n* inflammatory bowel disease.\n* inability to co-operate and give informed consent.\n* diffuse peritonitis.\n* antibiotic documented allergy \\& allergy to contrast media .\n* Patients with serious comorbid conditions DM \\& renal insufficiency, serum creatinine \\> 150 μmol\u002Fl .\n* Pregnant \\& lactating patient.\n* Patients with bleeding diathesis and those on anticoagulants.\n* Patients with advanced malignancies \\& patient on immunosuppressive drugs .\n* Patients with previous appendectomy.\n* Extreme of age.",true,"ALL","16 Years","60 Years",{"count":64,"type":65},100,"ESTIMATED","2 Days","OBSERVATIONAL","From this study, it can be concluded that patients who meet the following criteria are more likely to fail expectant management and thus should not be considered for the NOM of uncomplicated acute appendicitis. These include the duration of symptoms before presenting to a surgical emergency , the presence of fever within 24 hours of presenting to a surgical emergency, TLC cells\u002FdL, CRP mg\u002FL, appendix diameter mm, modified Alvarado score , and adult appendicitis score .",[70],"Conservative Management",[72],"Appendicitis","NOT_YET_RECRUITING","2025-02-13",{"date":76,"type":77},"2025-02-17","ACTUAL",{"date":79,"type":65},"2025-06-22",{"date":81,"type":65},"2025-12-02",{"name":48,"class":6},1]