[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100554820":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":32,"centralContacts":36,"locations":44,"responsibleParty":58,"collaborators":10,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":10,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":10,"maxAge":10,"enrollmentInfo":68,"targetDuration":10,"studyType":71,"phases":10,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":77,"whyStopped":10,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"First Affiliated Hospital Xi'an Jiaotong University","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Left ventricle group",null,"The patients mainly had thickened myocardial wall with a thin, compacted epicardial layer and a thicker endocardial layer, and were diagnosed with LVNC.",[13],"Biological: Diagnosis of NVM",{"label":15,"type":10,"description":16,"interventionNames":17},"Right ventricle group","The patients mainly had thickened myocardial wall with a thin, compacted epicardial layer and a thicker endocardial layer, and were diagnosed with right NVM.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Two sided ventricle group","The patients mainly had thickened myocardial wall with a thin, compacted epicardial layer and a thicker endocardial layer, and were diagnosed with right and left ventricle NVM.",[13],[23,28,30],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":10},"BIOLOGICAL","Diagnosis of NVM","The term 'left ventricular non-compaction' (LVNC) has been used to describe a ventricular phenotype characterized by prominent LV trabeculae and deep intertrabecular recesses. The myocardial wall is often thickened with a thin,compacted epicardial layer and a thickened myocardial layer. In some patients, this abnormal trabecular architecture is associated with LV dilatation and systolic dysfunction. Left ventricular non-compaction is frequently a familial trait and is associated with variants in a range of genes, including those encoding proteins of the sarcomere, Z-disc, cytoskeleton, and nuclear envelope.",[9],{"type":24,"name":25,"description":26,"armGroupLabels":29,"otherNames":10},[15],{"type":24,"name":25,"description":26,"armGroupLabels":31,"otherNames":10},[19],[33],{"name":34,"affiliation":5,"role":35},"Yang Yan","PRINCIPAL_INVESTIGATOR",[37,41],{"name":34,"role":38,"phone":39,"phoneExt":10,"email":40},"CONTACT","+862985323869","yangyan3@xjtu.edu.cn",{"name":42,"role":38,"phone":39,"phoneExt":10,"email":43},"Guoliang Li","liguoliang_med@163.com",[45],{"facility":46,"status":10,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":10},"First Affiliated Hospital of Xi'an Jiantong University","Xi'an","Shaanxi","710061","China","CN",{"type":53,"coordinates":54},"Point",[55,56],108.92861,34.25833,{"lat":56,"lon":55},{"type":59,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100554820","risk-stratification-and-early-prevention-strategies-for-non-compaction-of-ventricular-myocardium-captain-100554820",false,"NCT06504056","Risk Stratification and Early Prevention Strategies for Non-compaction of Ventricular Myocardium (CAPTAIN)","Risk Stratification and Early Prevention Strategies for Non-compaction of Ventricular Myocardium (CAPTAIN): a Multicenter, Retrospective-prospective, Cohort Study","Inclusion Criteria:\n\n* The diagnosis of nvm was confirmed by cardiac ultrasound, electrocardiogram, magnetic resonance angiography, pathological examination and gene sequencing.\n* Patients or their families agreed to participate in the study and authorized informed consent.\n\nExclusion Criteria:\n\n* Incomplete clinical data.\n* Do not agree to the inclusion or refuse to authorize the informed consent.","ALL",{"count":69,"type":70},2000,"ESTIMATED","OBSERVATIONAL","This study intends to retrospectively-prospectively enroll NVM patients from multiple centers to establish a natural population cohort of NVM patients. By collecting clinical data and biological samples from surgical patients, the investigators will construct a prognosis prediction system for NVM, optimize risk stratification, explore new strategies for the early prevention and treatment of NVM, and improve the efficiency of clinical treatment of NVM patients.",[74],"Isolated Noncompaction of the Ventricular Myocardium",[74,76],"Prognostic factors","NOT_YET_RECRUITING","2024-07-19",{"date":80,"type":81},"2024-07-22","ACTUAL",{"date":83,"type":70},"2024-10-30",{"date":85,"type":70},"2030-09-01",{"name":5,"class":6},1]