[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637067":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":41,"locations":51,"responsibleParty":65,"collaborators":25,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":25,"eligibilityCriteria":75,"healthyVolunteers":76,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":25,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":89,"overallStatus":93,"whyStopped":25,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Misr University for Science and Technology","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A (n=35): Ultrasound-guided RISS block.","EXPERIMENTAL","The patient will be positioned in the lateral decubitus with the ipsilateral arm abducted to move the scapula laterally and open the intercostal and subscapular spaces. A high-frequency linear probe (10-14 MHz) will be applied 1-2 cm medial to the medial scapular border in an oblique-sagittal plane at the T5-T6 level. Using an in-plane approach, a 22 G, 80 mm block needle will be advanced from superomedial to inferolateral (cephalocaudal) until the tip lies between RM and ICM. After negative aspiration and hydrodissection with 1-2 ml saline, 10 ml of the prepared solution (1% lidocaine + 0.25% bupivacaine + 4 mg dexamethasone) will be injected in 5 ml aliquots, with real-time observation of spread deep to RM. The probe will then be slid caudally and laterally to the T8-T9 level to visualize the fascial plane at the mid-axillary line between the serratus anterior (SA) muscle and the external intercostal muscle to inject the other 10 ml of local anesthetic.",[13],"Procedure: Group A (n=35): Ultrasound-guided RISS block (RISS):",{"label":15,"type":16,"description":17,"interventionNames":18},"Group B (n=35): Receiving ultrasound-guided lower thoracic ESP block","ACTIVE_COMPARATOR","The patient will be positioned laterally. A linear probe will be placed 3 cm lateral to the posterior midline at the T8-T9 level to identify the transverse process (TP) and erector spinae muscle (ESM). A 22 G, 80 mm Echogenic block needle will be advanced in-plane from cranial to caudal until the tip rests deep to ESM but superficial to the TP. After negative aspiration, 20 ml of the prepared solution (1% lidocaine + 0.25% bupivacaine + 4 mg dexamethasone) will be injected in 5 ml aliquots, with real-time ultrasound confirmation of longitudinal spread cranially and caudally along the fascial plane. The block will be performed bilaterally following the same stepsA solution composed of 20 ml mixed xylocaine 1% + 0.25 % bupivacaine + 4 mg dexamethasone on each side.",[19],"Procedure: Group B (n=35): Ultrasound-guided lower thoracic ESP block",[21,26],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Group A (n=35): Ultrasound-guided RISS block (RISS):",[9],null,{"type":22,"name":27,"description":17,"armGroupLabels":28,"otherNames":25},"Group B (n=35): Ultrasound-guided lower thoracic ESP block",[15],[30,34,38],{"name":31,"affiliation":32,"role":33},"Manar M ElKholy, Profesor","Prof. of Anesth, Kasr Alainy hospital, Faculty of Medicine, Cairo University","STUDY_CHAIR",{"name":35,"affiliation":36,"role":37},"Mohamed Abdelaziz Taha, Assist. Prof.","Assist. Prof. of Anesth, Souad Kafafi University hospital, Faculty of Medicine, MUST","STUDY_DIRECTOR",{"name":39,"affiliation":40,"role":37},"Ahmed SK Elkhodary, Lecturer","Lecturer of surgery at Souad Kafafi University hospital, Faculty of Medicine, MUST",[42,47],{"name":43,"role":44,"phone":45,"phoneExt":25,"email":46},"Emad LM Ahmed, Lecturer","CONTACT","+201006531896","emad.ahmmed@must.edu.eg",{"name":48,"role":44,"phone":49,"phoneExt":25,"email":50},"Mohamed M Ahmed, Resident","0201147888382","Manmoh980@gmail.com",[52],{"facility":53,"status":25,"city":54,"state":55,"zip":56,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":25},"Souad Kafafi University Hospital (SKUH), Faculty of Medicine, MUST","Giza","Giza Governorate","15525","Egypt","EG",{"type":60,"coordinates":61},"Point",[62,63],31.20861,30.00944,{"lat":63,"lon":62},{"type":66,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Emad Lotfy Mohammed Ahmed","lecturer of anesthesia, SICU and pain management, Faculty of medicine.","100637067","riss-versus-lower-thoracic-esp-block-for-analgesia-after-laparoscopic-abdominal-surgery-a-randomized-trial-100637067",false,"NCT07593300","RISS Versus Lower Thoracic ESP Block for Analgesia After Laparoscopic Abdominal Surgery: A Randomized Trial","Analgesic Efficacy of Ultrasound-Guided Rhomboid Intercostal and Subserratus (RISS) Block Versus Lower Thoracic Erector Spinae Plane Block (ESPB) After Abdominal Laparoscopic Surgery","Inclusion Criteria:\n\n* Patients scheduled for laparoscopic abdominal surgery (e.g., cholecystectomy, colectomy, sleeve gastrectomy, hernia repair, appendectomy).\n* Age from 18 - 60 years old.\n* Both sexes.\n* American Society of Anesthesiology (ASA) classification I, II. (i.e., ASA I: a normal healthy patient; ASA II: patients with mild controlled systemic disease.\n\nExclusion Criteria:\n\n* Patients who refuse the research consent.\n* Allergy to local anesthetic drugs.\n* Cardiac arrhythmia.\n* Bleeding tendency (including pre-existing blood disease and patients on full anticoagulant therapy).\n* Morbid obese patients (BMI\\>35 kg\u002Fm2)\n* Vascular compromise of lower extremity (e.g., Burger disease, Raynaud's disease).\n* Connective tissue disease (e.g., Scleroderma).\n* Suspected malignancy or intra-abdominal infection.",true,"ALL","18 Years","60 Years",{"count":81,"type":82},70,"ESTIMATED","INTERVENTIONAL",[85],"NA","The goal of this clinical trial is to investigate the analgesic efficacy of ultrasound-guided Romboid Intercostal and Subserratus (RISS) block versus lower thoracic Erector Spinae Plane (ESP) block after laparoscopic abdominal surgery. The main questions it aims to answer are:\n\nDoes ultrasound-guided Romboid Intercostal and Subserratus (RISS) block is effective as the lower thoracic Erector Spinae Plane (ESP) block for intra and postoperative analgesia after laparoscopic abdominal surgery for the first 24 hours? What complications do participants have when doing these interventions?\n\nResearchers will compare the analgesic efficacy of ultrasound-guided Romboid Intercostal and Subserratus (RISS) block with the lower thoracic Erector Spinae Plane (ESP) block after laparoscopic abdominal surgery.\n\nParticipants will:\n\nStart general anesthesia and be given either block according to the randomization chart.\n\nThe blood pressure and heart rate will be measured at intervals to determine if the participants need extra intraoperative analgesics.\n\nNumerical Rating Scale (NRS) will be used postoperatively to test pain severity.\n\nRescue morphine analgesia will be measured and compared in both groups.\n\nAny complications will be reported.\n\nPatient and surgeon satisfaction will be measured.",[88],"Pain After Surgery",[90,91,92],"Erector Spine Plane Block","Laparoscopic surgery","Rhomboid Intercostal block","NOT_YET_RECRUITING","2026-05-13",{"date":96,"type":97},"2026-05-18","ACTUAL",{"date":99,"type":82},"2026-05-20",{"date":101,"type":82},"2026-12-31",{"name":5,"class":6},1]