[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100521528":3},{"organization":4,"armGroups":7,"interventions":53,"overallOfficials":61,"centralContacts":77,"locations":87,"responsibleParty":124,"collaborators":10,"id":126,"slug":127,"hasResults":128,"nctId":129,"briefTitle":130,"officialTitle":131,"acronym":10,"eligibilityCriteria":132,"healthyVolunteers":128,"sex":133,"minAge":134,"maxAge":10,"enrollmentInfo":135,"targetDuration":10,"studyType":138,"phases":10,"briefSummary":139,"conditions":140,"keywords":146,"overallStatus":89,"whyStopped":10,"lastUpdateSubmitDate":149,"lastUpdatePostDateStruct":150,"startDateStruct":153,"completionDateStruct":155,"leadSponsor":157,"locationsCount":158},{"fullName":5,"class":6},"RIVER Foundation","OTHER",[8,14,17,21,24,27,31,34,37,40,44,47,50],{"label":9,"type":10,"description":11,"interventionNames":12},"Chronic Pain",null,"Drug: Ketamine The efficacy of the various approaches to prescribing Ketamine currently in use off-label. The focus will be to include ketamine research within the treatment plan of those with chronic conditions. A RIVER Ketamine protocol will be developed",[13],"Drug: Ketamine",{"label":15,"type":10,"description":11,"interventionNames":16},"Anxiety",[13],{"label":18,"type":10,"description":19,"interventionNames":20},"Veterans and First Responders","The efficacy of the various approaches to prescribing Ketamine currently in use off-label. The focus will be to include ketamine research within the treatment plan of those with chronic conditions. A RIVER Ketamine protocol will be developed",[13],{"label":22,"type":10,"description":11,"interventionNames":23},"Depression",[13],{"label":25,"type":10,"description":11,"interventionNames":26},"Trauma",[13],{"label":28,"type":10,"description":29,"interventionNames":30},"Auricular Chronic Pain","Auricular Therapy (Ear acupuncture)\n\n1. National Acupuncture Detoxification Association\n2. Battlefield Acupuncture",[13],{"label":32,"type":10,"description":29,"interventionNames":33},"Auricular Anxiety",[13],{"label":35,"type":10,"description":29,"interventionNames":36},"Auricular Depression",[13],{"label":38,"type":10,"description":29,"interventionNames":39},"Auricular Trauma",[13],{"label":41,"type":10,"description":42,"interventionNames":43},"Chronic Pain MH","4\\. Millennium Health The Phase 2 Protocol (P2P) has entered its 4th year of application in those with symptoms associated with all forms of traumatic brain injury (T.B.I.). Listening to any of the following Joe Rogan Experience podcasts, 1589, 1056, or 700, will provide a number of discussions on this topic. Since the 2020 pilot study with active duty Marines (U.S.M.C.), looking at the benefits of a 100% nutraceutical approach to T.B.I., precipitated changes in mental and physical health, we had the start to developing the P2P. With over 8,000 participants, we see the benefits derived from the 2023 Phase 2 Protocol.",[13],{"label":45,"type":10,"description":42,"interventionNames":46},"Anxiety MH",[13],{"label":48,"type":10,"description":42,"interventionNames":49},"Depression MH",[13],{"label":51,"type":10,"description":42,"interventionNames":52},"Tramua MH",[13],[54],{"type":55,"name":56,"description":57,"armGroupLabels":58,"otherNames":59},"DRUG","Ketamine","The use of ketamine in chronic conditions.",[15,45,32,28,35,38,9,41,22,48,51,25,18],[60],"Ketalar",[62,65,68,70,72,74],{"name":63,"affiliation":5,"role":64},"Dharma Rose, D.O. M.S.","PRINCIPAL_INVESTIGATOR",{"name":66,"affiliation":5,"role":67},"Frank Yurseak, Ph.D.","STUDY_CHAIR",{"name":69,"affiliation":5,"role":64},"Jeffery Newton",{"name":71,"affiliation":5,"role":64},"Alejandro Fernandez",{"name":73,"affiliation":5,"role":64},"James Taggart, MD",{"name":75,"affiliation":5,"role":76},"Ed Lesofski, MS","STUDY_DIRECTOR",[78,83],{"name":79,"role":80,"phone":81,"phoneExt":10,"email":82},"Ed Lesofski, M.S.","CONTACT","406-431-4890","ed@riverofchange.org",{"name":84,"role":80,"phone":85,"phoneExt":10,"email":86},"James Taggart, M.D.","415--713-6554","info@riverofchange.org",[88,105],{"facility":5,"status":89,"city":90,"state":91,"zip":92,"country":93,"countryCode":94,"cosmosGeoPoint":95,"geoPoint":100,"contacts":101},"RECRUITING","Bigfork","Montana","59911","United States","US",{"type":96,"coordinates":97},"Point",[98,99],-114.07261,48.06329,{"lat":99,"lon":98},[102,103],{"name":75,"role":80,"phone":81,"phoneExt":10,"email":82},{"name":104,"role":80,"phone":81,"phoneExt":10,"email":86},"Jeff Newton",{"facility":106,"status":89,"city":107,"state":91,"zip":108,"country":93,"countryCode":94,"cosmosGeoPoint":109,"geoPoint":113,"contacts":114},"RIVER Telehealth","Helena","59601",{"type":96,"coordinates":110},[111,112],-112.03611,46.59271,{"lat":112,"lon":111},[115,117,118,120,122],{"name":75,"role":80,"phone":116,"phoneExt":10,"email":82},"406-465-9504",{"name":73,"role":64,"phone":10,"phoneExt":10,"email":10},{"name":119,"role":64,"phone":10,"phoneExt":10,"email":10},"Frank Yurasek, PhD",{"name":121,"role":64,"phone":10,"phoneExt":10,"email":10},"Edward Lesofski, MS",{"name":69,"role":123,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"type":125,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100521528","river-at-home-ketamine-protocols-100521528",false,"NCT06070766","RIVER At Home Ketamine Protocols","Can Digital Health Technology Guide Medical Providers, in Treating Chronic Conditions With RIVER Ketamine Protocols Safely at Home?","Inclusion Criteria:\n\nMust have an identifiable chronic condition.\n\nExclusion Criteria:\n\nHealthy Population","ALL","18 Years",{"count":136,"type":137},50000,"ESTIMATED","OBSERVATIONAL","Multiple site studies with the recruitment of other sub-investigators and sites. It's sobering to consider how chronic illness makes us more vulnerable to suicidal thoughts and behavior. However, the existence of multiple risk factors also means that there are numerous ways to intervene. Addressing and improving even one risk area will reverberate and improve other areas and the quality of life.\n\nRIVER Foundation is completing a 500-participant pilot study researching the safety of oral and nasal ketamine at home with no therapy. The pilot study examined three psychological scales: P.H.Q. 9, G.A.D. 7, and PCL5 scores. The interim report will be available in Nov 2023 with a final report in June 2024.\n\nThe lack of knowledge for the average medical practitioner makes ketamine a boutique medicine, often costly and unaffordable to those in need. Yet daily medical providers are eliminating ketamine as a choice in the treatment of chronic conditions.\n\nThe pilot study demonstrated the who, and where. The who, was adults with a chronic condition. The pilot study demonstrated the majority of those who could use ketamine are not receiving it due to cost. According to the 500-participant study, ketamine is safe and effective for at-home use thus demonstrating the where (at home with no supervision).",[141,9,142,143,144,145],"Chronic Condition","Chronic Disease","Major Depressive Disorder","Post Traumatic Stress Disorder","Anxiety Disorders",[56,147,148],"Neuroinflammation","Auricular","2024-11-22",{"date":151,"type":152},"2024-11-26","ACTUAL",{"date":154,"type":152},"2023-10-01",{"date":156,"type":137},"2029-04-01",{"name":5,"class":6},2]