[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100612838":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":19,"locations":25,"responsibleParty":44,"collaborators":10,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":10,"eligibilityCriteria":52,"healthyVolunteers":49,"sex":53,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":10,"studyType":59,"phases":10,"briefSummary":60,"conditions":61,"keywords":10,"overallStatus":28,"whyStopped":10,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},{"fullName":5,"class":6},"University of Maryland, Baltimore","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"patients with benign tracheal stenosis undergoing either endoscopic or surgical treatment",null,[12],"Procedure: Biopsy or surgery",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"PROCEDURE","Biopsy or surgery","The tissue will be obtained from biopsy or surgical resection. All the \"intervention\" will be performed for clinical needs. The tissue used in the study will be considered as discarded tissue",[9],[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Chenchen Zhang, MD","CONTACT","14103288141","chenchen.zhang@som.umaryland.edu",[26],{"facility":27,"status":28,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"University of Maryland","RECRUITING","Baltimore","Maryland","21201","United States","US",{"type":35,"coordinates":36},"Point",[37,38],-76.61219,39.29038,{"lat":38,"lon":37},[41],{"name":42,"role":22,"phone":43,"phoneExt":10,"email":24},"Chenchen Zhang","4103288141",{"type":45,"investigatorFullName":42,"investigatorTitle":46,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Assistant professor","100612838","rna-sequencing-of-discarded-tracheal-stenosis-tissue-to-characterize-cellular-and-molecular-pathogenesis-100612838",false,"NCT07258784","RNA Sequencing of Discarded Tracheal Stenosis Tissue to Characterize Cellular and Molecular Pathogenesis","Inclusion Criteria:\n\n* Patients with benign tracheal stenosis\n\nExclusion Criteria:\n\n* Malignancy. active infection","ALL","18 Years","80 Years",{"count":57,"type":58},10,"ESTIMATED","OBSERVATIONAL","Benign tracheal stenosis is a rare but potentially life-threatening condition, typically resulting from fibroinflammatory scarring. It can be secondary to iatrogenic etiologies such as intubation or tracheostomy , as well as autoimmune diseases and being idiopathic. Patients typically undergoes endoscopic or surgical interventions to open up the airways. This project will analyze resected or biopsied tissue from patients with benign tracheal stenosis to define disease-specific RNA expression profiles.",[62,63],"Tracheal Stenosis","Subglottic Stenosis","2025-11-20",{"date":66,"type":67},"2025-12-02","ACTUAL",{"date":69,"type":67},"2025-09-11",{"date":71,"type":58},"2026-12-31",{"name":5,"class":6},1]