[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640932":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":30,"locations":36,"responsibleParty":54,"collaborators":24,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":60,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":24,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":39,"whyStopped":24,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Kanuni Sultan Suleyman Training and Research Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Robot-Assisted Gait Training Group","ACTIVE_COMPARATOR","Participants in this group will receive a standard rehabilitation program in addition to robot-assisted gait training. The intervention will be applied five days per week for six weeks.",[13],"Device: robot -assisted gait training",{"label":15,"type":10,"description":16,"interventionNames":17},"Quadriceps NMES Group","Participants in this group will receive a standard rehabilitation program in addition to quadriceps neuromuscular electrical stimulation (NMES). The intervention will be applied five days per week for six weeks.",[18],"Other: Quadriceps Neuromuscular Electrical Stimulation (NMES)",[20,25],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Quadriceps Neuromuscular Electrical Stimulation (NMES)","Quadriceps neuromuscular electrical stimulation (NMES) applied to the quadriceps muscle in addition to a standard rehabilitation program including posture exercises, balance and coordination training, relaxation, and functional gait training in patients with Parkinson's disease. This intervention specifically targets improvement of quadriceps muscle strength and neuromuscular activation.",[15],null,{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":24},"DEVICE","robot -assisted gait training","Robot-assisted gait training applied in addition to a standard rehabilitation program including posture exercises, balance and coordination training, relaxation, and functional gait training in patients with Parkinson's disease. This intervention is designed to improve gait performance, balance, and functional mobility.",[9],[31],{"name":32,"role":33,"phone":34,"phoneExt":24,"email":35},"dilek Ün Oğuzhanasiltürk, MD","CONTACT","+90 5056367184","dilekunoguzhan@gmail.com",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":24,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey","RECRUITING","Küçükçekmece","Istanbul","34303","Turkey (Türkiye)",{"type":45,"coordinates":46},"Point",[47,48],28.77123,40.99104,{"lat":48,"lon":47},[51],{"name":52,"role":33,"phone":53,"phoneExt":24,"email":35},"Dilek Ün Oğuzhanasiltürk, MD","+905056367184",{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Dilek ün oguzhanasilturk","Specialist in Physical Medicine and Rehabilitation","100640932","robot-assisted-gait-training-vs-nmes-in-parkinsons-disease-100640932",false,"NCT07589296","Robot-Assisted Gait Training vs NMES in Parkinson's Disease","Comparative Effects of Robot-Assisted Gait Training and Quadriceps Neuromuscular Electrical Stimulation Added to Standard Exercise Rehabilitation on Balance, Gait, Disease Severity, and Quadriceps Muscle Adaptations in Patients With Parkinson Disease: A Prospective Randomized Assessor-Blinded Clinical Trial","ROBO-NMES-PD","Inclusion Criteria:\n\n* Diagnosis of Parkinson's disease according to established clinical criteria\n* Age between 40 and 80 years\n* Hoehn and Yahr stage II-III\n* Ability to walk independently with or without assistive devices\n* Stable medical treatment for at least 4 weeks prior to study enrollment\n* Ability to understand and follow instructions\n* Willingness to participate and provide written informed consent\n\nExclusion Criteria:\n\n* Severe cognitive impairment or inability to follow instructions\n* Hoehn and Yahr stage IV-V Parkinson's disease\n* Severe musculoskeletal disorders affecting gait (e.g., advanced osteoarthritis, recent fracture)\n* History of lower extremity surgery within the last 6 months\n* Severe cardiovascular or respiratory disease limiting exercise participation\n* Presence of other neurological disorders affecting mobility (e.g., stroke, multiple sclerosis)\n* Contraindications to electrical stimulation (e.g., pacemaker, implanted electronic devices)\n* Skin lesions or infections at electrode placement sites\n* Participation in another structured rehabilitation program within the last 3 months","ALL","40 Years","80 Years",{"count":70,"type":71},40,"ESTIMATED","INTERVENTIONAL",[74],"NA","This prospective, randomized, assessor-blinded clinical trial aims to compare the effects of robot-assisted gait training and quadriceps neuromuscular electrical stimulation (NMES) when added to a standard exercise rehabilitation program in patients with Parkinson disease.\n\nParticipants will be randomly assigned to two parallel groups. Both groups will receive a standard rehabilitation program, while one group will additionally undergo robot-assisted gait training and the other group will receive quadriceps NMES. The interventions will be administered five days per week for six weeks.\n\nClinical outcomes, including balance, functional mobility, gait performance, and disease severity, will be evaluated at baseline, post-treatment, and follow-up (week 14). In addition, ultrasound-based assessments of quadriceps muscle thickness and cross-sectional area will be performed to investigate muscle adaptations.\n\nThe results of this study are expected to provide comparative evidence regarding the effectiveness of these two rehabilitation approaches and contribute to optimizing rehabilitation strategies in Parkinson disease.",[77],"Parkinson Disease (PD)",[79,80,81,82,83,84,85,86],"Parkinson disease","Robot-assisted gait training","Neuromuscular electrical stimulation","Quadriceps muscle","Rehabilitation","Balance","Gait","Ultrasonography","2026-05-11",{"date":89,"type":90},"2026-05-15","ACTUAL",{"date":92,"type":90},"2026-04-15",{"date":94,"type":71},"2027-06-15",{"name":5,"class":6},1]