[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100494970":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":42,"responsibleParty":65,"collaborators":26,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":71,"sex":77,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":26,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":26,"overallStatus":45,"whyStopped":26,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Jinling Hospital, China","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"CCTA-based strategy group","ACTIVE_COMPARATOR","Subjects will be managed following the CCTA -based coronary heart disease prevention strategy for lipid-lowering treatment and follow-up.",[13],"Diagnostic Test: Coronary Computed Tomography Angiography",{"label":15,"type":16,"description":17,"interventionNames":18},"Chinese guidelines for lipid management (2023)","SHAM_COMPARATOR","The baseline assessment will be completed on the same day as consent is gained. Every subjects will complete a comprehensive assessment including questionnaires and objective assessments.",[19],"Other: Traditional cardiovascular risk stratification",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIAGNOSTIC_TEST","Coronary Computed Tomography Angiography","Intervention strategies according to CCTA results",[9],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Traditional cardiovascular risk stratification","Intervention strategies according to traditional cardiovascular risk stratification based on Chinese guidelines for lipid management (2023)",[15],[32],{"name":33,"affiliation":34,"role":35},"Trail Manager","Jinling Hospital,Nanjing University School of Medicine,Nanjing,China","STUDY_CHAIR",[37],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"Longjiang Zhang, MD","CONTACT","13405833167","kevinzhlj@163.com",[43],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Research Institute Of Medical Imaging Jinling Hospital","RECRUITING","Nanjing","Jiangsu","210018","China","CN",{"type":52,"coordinates":53},"Point",[54,55],118.77778,32.06167,{"lat":55,"lon":54},[58,61],{"name":59,"role":39,"phone":60,"phoneExt":26,"email":41},"longjiang Zhang, MD","13405833176",{"name":62,"role":39,"phone":63,"phoneExt":26,"email":64},"Xiang Guo, MD","15820077389","sdtzgx@163.com",{"type":66,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","Zhang longjiang,MD","Principal Investigator : Zhang longjiang","100494970","role-of-coronary-cta-on-lipid-management-and-risk-factors-control-in-an-asymptomatic-chinese-population-100494970",false,"NCT05725096","Role of Coronary CTA on Lipid Management and Risk Factors Control in an Asymptomatic Chinese Population","Role of the Screening with Coronary Computed Tomography Angiography on Lipid Management and Risk Factors Control in an Asymptomatic Chinese Population: a Community-based, Prospective Randomised Trial","RESPECT2","Inclusion Criteria:\n\n1. Nanjing residents who have no plans to leave in the next 5 years\n2. Aged from 40 to 69 years\n3. Free of any known clinically cardiovascular disease Able to comprehend and sign an informed consent form\n\nExclusion Criteria:\n\n1. Serious liver dysfunction, defined as AST or ALT \\> 3 times the normal upper limit\n2. Chronic kidney disease (CKD) \\> stage 4, defined as eGFR \\\u003C 30 ml\u002Fmin\u002F1.73 m2\n3. Prior CCTA or invasive coronary angiography within the last 5 years\n4. Any contraindications for CCTA\n5. Previous use of statin or non-statin lipid-lowering medication (such as ezetimibe, PCSK9 inhibitor and XueZhiKang)\n6. Life expectancy \\\u003C 3 years\n7. Other reasons the researcher deems inappropriate to attend","ALL","40 Years","69 Years",{"count":81,"type":82},3400,"ESTIMATED","INTERVENTIONAL",[85],"NA","The primary objective of this study is to determine whether coronary computed tomography angiography (CCTA) -based coronary heart disease(CHD) prevention strategy improves lipid-lowering treatment and cardiovascular risk factor control compared with traditional CHD prevention strategy, guided by a cardiovascular risk score.",[88,89,90,91],"Statin","Cardiovascular Risk Factors","Primary Prevention","Adherence, Medication","2024-11-25",{"date":94,"type":95},"2024-11-26","ACTUAL",{"date":97,"type":95},"2023-06-28",{"date":99,"type":82},"2027-06",{"name":67,"class":6},1]