[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100413679":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":13,"locations":18,"responsibleParty":35,"collaborators":7,"id":37,"slug":38,"hasResults":39,"nctId":40,"briefTitle":41,"officialTitle":42,"acronym":7,"eligibilityCriteria":43,"healthyVolunteers":39,"sex":44,"minAge":45,"maxAge":7,"enrollmentInfo":46,"targetDuration":7,"studyType":49,"phases":7,"briefSummary":50,"conditions":51,"keywords":7,"overallStatus":21,"whyStopped":7,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":62},{"fullName":5,"class":6},"M.D. Anderson Cancer Center","OTHER",null,[9],{"name":10,"affiliation":11,"role":12},"Anusha Thomas, MD","MD Anderson Cancer Center, Houston, Texas","PRINCIPAL_INVESTIGATOR",[14],{"name":10,"role":15,"phone":16,"phoneExt":7,"email":17},"CONTACT","713-563-9600","asthomas1@mdanderson.org",[19],{"facility":20,"status":21,"city":22,"state":23,"zip":24,"country":25,"countryCode":26,"cosmosGeoPoint":27,"geoPoint":32,"contacts":33},"M D Anderson Cancer Center","RECRUITING","Houston","Texas","77090","United States","US",{"type":28,"coordinates":29},"Point",[30,31],-95.36327,29.76328,{"lat":31,"lon":30},[34],{"name":10,"role":15,"phone":16,"phoneExt":7,"email":17},{"type":36,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100413679","role-of-diet-on-the-microbiome-of-the-digestive-system-100413679",false,"NCT04666727","Role of Diet on the Microbiome of the Digestive System","The Role of Diet and the Microbiome in Inducing Somatic Mutations in Colorectal Epithelial Cells and Its Predisposition to Carcinogenesis - A Pilot Study","Inclusion Criteria:\n\n* GROUP I: Patients presenting for a screening colonoscopy\n\n  * GROUP I: Age of 45 and above\n  * GROUP I: Strict vegetarian diet, determined by using diet history questionnaire 3.0 National Institutes of Health (NIH)\n  * GROUP I: Non smoker\n  * GROUP I: Ability to understand and willingness to sign an informed consent form, complete web based dietary assessment and provide stool, colonic mucosa and blood samples\n  * GROUP II: Patients presenting for a screening colonoscopy\n  * GROUP II: Age of 45 and above\n  * GROUP II: Omnivorous diet\n  * GROUP II: Non smoker\n  * GROUP II: Ability to understand and willingness to sign an informed consent form, complete web based dietary assessment and provide stool, colonic mucosa and blood sample\n\nExclusion Criteria:\n\n* • Current smokers (nicotine abuse only)\n\n  * Positive family history of colon cancer or colon cancer related syndromes\n  * Recent use of antibiotics in 1 month\n  * History of inflammatory bowel disease, and\u002For radiation enteritis or colitis\n  * Pregnant and breastfeeding women\n  * Women of child-bearing potential who have positive urine or serum pregnancy test\n  * Heavy drinker (defined as more than 14 drinks per week)\n  * Currently using anti-flatulence medications, probiotics and\u002For fiber supplements\n  * Major dietary restrictions and\u002For following a special diet\n  * Patient with positive fecal test\u002Fsymptoms","ALL","45 Years",{"count":47,"type":48},30,"ESTIMATED","OBSERVATIONAL","This study is to learn more about how diet affects the microbiome (bacteria and microorganisms) of the digestive system. Researchers want to learn if this, in turn, has an effect on if and how people then develop colorectal cancer.",[52],"Colorectal Carcinoma","2026-05-22",{"date":55,"type":56},"2026-05-26","ACTUAL",{"date":58,"type":56},"2020-09-29",{"date":60,"type":48},"2027-01-01",{"name":5,"class":6},1]