[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622731":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":34,"centralContacts":39,"locations":44,"responsibleParty":59,"collaborators":61,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":29,"eligibilityCriteria":70,"healthyVolunteers":66,"sex":71,"minAge":72,"maxAge":29,"enrollmentInfo":73,"targetDuration":29,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":47,"whyStopped":29,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"The University of Hong Kong","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Exercise with telehealth group","EXPERIMENTAL","Participants will attend telehealth physiotherapy class for exercise. Smoking cessation advice will be given.",[13],"Behavioral: Exercise with telehealth group",{"label":15,"type":16,"description":17,"interventionNames":18},"Exercise group","ACTIVE_COMPARATOR","Participants will exercise with walking. Smoking cessation advice will be given.",[19],"Behavioral: Exercise group",{"label":21,"type":16,"description":22,"interventionNames":23},"No exercise group","No exercise instruction will be given. Participants are encouraged to exercise. Smoking cessation advice will be given.",[24],"Behavioral: No exercise group",[26,30,32],{"type":27,"name":9,"description":11,"armGroupLabels":28,"otherNames":29},"BEHAVIORAL",[9],null,{"type":27,"name":15,"description":17,"armGroupLabels":31,"otherNames":29},[15],{"type":27,"name":21,"description":22,"armGroupLabels":33,"otherNames":29},[21],[35],{"name":36,"affiliation":37,"role":38},"King Pui Florence Chan, MD","he University of Hong Kong, Queen Mary Hospital","PRINCIPAL_INVESTIGATOR",[40],{"name":36,"role":41,"phone":42,"phoneExt":29,"email":43},"CONTACT","+852 22553741","kpfchan@hku.hk",[45],{"facility":46,"status":47,"city":48,"state":29,"zip":29,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"The University of Hong Kong, Queen Mary Hospital","RECRUITING","Hong Kong","China","CN",{"type":52,"coordinates":53},"Point",[54,55],114.17469,22.27832,{"lat":55,"lon":54},[58],{"name":36,"role":41,"phone":42,"phoneExt":29,"email":43},{"type":60,"investigatorFullName":29,"investigatorTitle":29,"investigatorAffiliation":29,"oldNameTitle":29,"oldOrganization":29},"SPONSOR",[62],{"name":63,"class":6},"Queen Mary Hospital, Hong Kong","100622731","role-of-exercise-in-prism-and-subsequent-development-of-copd-100622731",false,"NCT07387432","Role of Exercise in PRISm and Subsequent Development of COPD","Role of Exercise in Functional Capacity of Smokers and Subsequent Development of Chronic Obstructive Pulmonary Disease","Inclusion Criteria:\n\n* Age 18 or above\n* Smoker\u002F ex-smoker\n* Spirometry shows PRISm, with FEV1\u002FFVC \\>= 0.7 and FEV1 \\\u003C80% predicted\n* Ambulatory to walk\n* Able to give informed consent\n\nExclusion Criteria:\n\n* Age below 18\n* Non-smoker\n* Spirometry does not show PRISm\u002F unable to perform spirometry\n* Requires assistance for walking\n* Unable to give informed consent","ALL","18 Years",{"count":74,"type":75},90,"ESTIMATED","INTERVENTIONAL",[78],"NA","Preserved Ratio Impaired Spirometry (PRISm) describes individual with spirometry findings of forced expiratory volume (FEV1) and forced vital capacity (FVC) ratio greater than 0.7 but with the FEV1 less than 80% predicted.\n\nWhile the spirometry findings of individuals with PRISm can be transited into obstructive pattern, remains at PRISm or become normal spirometry, limited evidence is on the role of exercise in the course of PRISm. This study aims to investigate the role of exercise, namely exercise with telehealth and walking exercise, together with smoking cessation advice, would alter the clinical course of PRISm.",[81],"Preserved Ratio Impaired Spirometry (PRISM)",[83,84,85,86,87],"Preserved ratio impaired spirometry","PRISm","exercise with telehealth","walking exercise","smoking cessation","2026-03-04",{"date":90,"type":91},"2026-03-06","ACTUAL",{"date":93,"type":91},"2025-07-14",{"date":95,"type":75},"2028-01",{"name":5,"class":6},1]