[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100565552":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":31,"locations":41,"responsibleParty":60,"collaborators":25,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":25,"eligibilityCriteria":68,"healthyVolunteers":69,"sex":70,"minAge":71,"maxAge":25,"enrollmentInfo":72,"targetDuration":25,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":82,"overallStatus":44,"whyStopped":25,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Postgraduate Institute of Dental Sciences Rohtak","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Pt with apicomarginal defects & interproximal bone loss receiving GTR","EXPERIMENTAL","Surgery performed using ACM membrane and PRF plug.",[13],"Procedure: Endodontic Micro-Surgery",{"label":15,"type":16,"description":17,"interventionNames":18},"Pt with apicomarginal defects & interproximal bone loss without GTR","ACTIVE_COMPARATOR","Surgery performed without ACM membrane and PRF plug.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Endodontic Micro-Surgery","Surgery performed using ACM membrane and PRF plug in test group \\& without membrane \\& PRF in control group.",[9,15],null,[27],{"name":28,"affiliation":29,"role":30},"Dr, Sanjay Tewari, MDS","PGIDS, Rohtak, Haryana, 124001","STUDY_DIRECTOR",[32,37],{"name":33,"role":34,"phone":35,"phoneExt":25,"email":36},"Dr. Shweta Mittal, MDS","CONTACT","9255596960","shwetagoelendo@gmail.com",{"name":38,"role":34,"phone":39,"phoneExt":25,"email":40},"Dr. Parichay Singhal, MDS","9717710642","Parichaysinghal11@gmail.com",[42],{"facility":43,"status":44,"city":45,"state":25,"zip":25,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Pgids Rohtak","RECRUITING","Haryāna","India","IN",{"type":49,"coordinates":50},"Point",[51,52],76.98056,29.61611,{"lat":52,"lon":51},[55,58],{"name":56,"role":34,"phone":39,"phoneExt":25,"email":57},"PARICHAY SINGHAL, PG STUDENT","parichaysinghal11@gmail.com",{"name":59,"role":34,"phone":35,"phoneExt":25,"email":25},"SHWETA MITTAL, MDS",{"type":61,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100565552","role-of-gtr-on-healing-outcome--quality-of-life-in-combined-endo-perio-lesions-with-communication-100565552",false,"NCT06643663","Role of GTR on Healing Outcome & Quality of Life in Combined Endo Perio Lesions With Communication","\"Role of Guided Tissue Regeneration on Healing Outcome & Quality of Life in Combined Endo Perio Lesions With Communication: A Randomized Controlled Trial\"","Inclusion Criteria:\n\n1. Patients of age 16yrs and above.\n2. Patients with apico-marginal defects and deep pocket upto apex of tooth.\n3. Failed primary root canal treatment.\n4. Presence of interproximal bone loss.\n5. Negative response to vitality test.\n6. ASA-1 or ASA- 2 according to the classification of the American Society of Anesthesiologists)\n\nExclusion criteria:\n\n1. Presence of vertical root fracture\n2. Presence of root perforations\n3. ASA-3 or ASA-4 according to the classification of the American Society of Anesthesiologists)\n4. Presence of root resorption\n5. Combined endodontic-periodontic lesions.\n6. Pregnancy",true,"ALL","16 Years",{"count":73,"type":74},30,"ESTIMATED","INTERVENTIONAL",[77],"NA","The recovery of periapical defects linked to periodontal communication frequently yields less satisfactory results. Numerous studies and case reports have highlighted the notable success achieved through the application of guided tissue regeneration techniques. More recently, autologous platelet concentrate plug \\& placental membrane have emerged as a treatment option for addressing such lesions. Nevertheless, there has been no study using PRF-Medium with ACM membrane on the healing of aforesaid lesion \\& quality of life assessment.",[80,81],"Periapical Diseases","Endodontic Disease",[83,84,85,86],"Guided tissue regeneration","healing","endo-perio lesions","endodontic surgery","2025-01-06",{"date":89,"type":90},"2025-01-08","ACTUAL",{"date":92,"type":90},"2024-05-23",{"date":94,"type":74},"2025-12-23",{"name":5,"class":6},1]