[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100584426":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":25,"locations":30,"responsibleParty":47,"collaborators":25,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":25,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":73,"overallStatus":77,"whyStopped":25,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"plasma rich growth factor (PRGF) (intervention or study group)","ACTIVE_COMPARATOR","plasma rich growth factor (PRGF) intervention or study group Has Surgical procedures \"von Langenbeck technique \" to repair cleft palate and placing plasma rich growth factors between nasal and palatal tissue then primary closure intraoperatively, then patient will come for follow up visit after surgery, 1st day, 3rd, 5th day and come for follow up visits at 1 week, 1 month and 3 months postoperative",[13],"Other: Plasma Rich in Growth Factors (PRGF)",{"label":15,"type":16,"description":17,"interventionNames":18},"placebo (control group)","PLACEBO_COMPARATOR","placebo (control group) Has Surgical procedures \"von Langenbeck technique \" to repair cleft palate primary closure, then patient will come for follow up visit after surgery, 1st day, 3rd, 5th day and come for follow up visits at 1 week, 1 month and 3 months postoperative",[19],"Other: Placebo",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Plasma Rich in Growth Factors (PRGF)","using prgf with closing primary cleft palate - isolated cleft palate Minutes before the surgery, 10-20 ml of venous blood from each patient. -The blood is centrifuged to obtain PRGF. -Fixed between nasal and palatal mucosa",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Placebo","primary closing cleft palate-isolated cleft palate",[15],[31],{"facility":32,"status":25,"city":33,"state":34,"zip":25,"country":35,"countryCode":36,"cosmosGeoPoint":25,"geoPoint":25,"contacts":37},"Faculty of Dentistry, Cairo University","Manial","Cairo Governorate","Egypt","EG",[38,43],{"name":39,"role":40,"phone":41,"phoneExt":25,"email":42},"sarah horia, M.Sc.","CONTACT","00201010014043","sarahhoria@gmail.com",{"name":44,"role":40,"phone":45,"phoneExt":25,"email":46},"El noman MK El shafie, lecturer","002001063999203","nomanmust@gmail.com",{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Sarah Samir Horia","assistant lecturer","100584426","role-of-plasma-rich-growth-factor-in-repair-primary-cleft-palate-100584426",false,"NCT06889181","Role of Plasma Rich Growth Factor in Repair Primary Cleft Palate","Evaluation of the Role of the Plasma-rich Growth Factor (PRGF) with Primary Cleft Palate Repair Versus Primary Cleft Palate Repair in Post-operative Wound Healing and Oronasal Fistula Occurrence, a Randomized Clinical Trial","PRGF","Inclusion Criteria:\n\n* systemically healthy patients (American Society of Anesthesiologists -ASA I and II); not older than 6-18 months\n* Patients with primary non-syndromic isolated cleft palate\n* Apprehensive to be in the study.\n\nExclusion Criteria:\n\n* Patients with recurrent palatal fistula\n* Existence of syndromic cleft palate\n* Blood diseases and platelet disorders (hematological disease)\n* Systematic disease radiotherapy or chemotherapy for malignancy",true,"ALL","6 Months","18 Months",{"count":64,"type":65},36,"ESTIMATED","INTERVENTIONAL",[68],"NA","Does the plasma-rich growth factor (PRGF) with primary cleft palate repair accelerate wound healing and prevent post-operative oronasal fistula occurrence?",[71,72],"Cleft Palate","Plasma Rich in Growth Factors",[74,75,76],"cleft palate","plasma rich growth factor","healing","NOT_YET_RECRUITING","2025-03-16",{"date":80,"type":81},"2025-03-21","ACTUAL",{"date":83,"type":65},"2025-04-01",{"date":85,"type":65},"2027-06-30",{"name":5,"class":6},1]