[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622282":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":21,"locations":27,"responsibleParty":49,"collaborators":20,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":20,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":20,"enrollmentInfo":60,"targetDuration":20,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":68,"overallStatus":73,"whyStopped":20,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Postgraduate Institute of Dental Sciences Rohtak","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Oral Lichen Planus","EXPERIMENTAL","Scaling and root planing will be conducted on Oral Lichen Planus cases with gingival involvement.",[13],"Procedure: subgingival instrumentation",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"PROCEDURE","subgingival instrumentation","Subgingival instrumentation like scaling and root planing of the recruited subject shall be done.",[9],null,[22],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},"Mala Kamboj, MDS","CONTACT","+919466902477","malskam@gmail.com",[28],{"facility":29,"status":20,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Post Graduate Institute of Dental Sciences","Rohtak","Haryana","124001","India","IN",{"type":36,"coordinates":37},"Point",[38,39],76.58917,28.89447,{"lat":39,"lon":38},[42,44,47],{"name":43,"role":24,"phone":25,"phoneExt":20,"email":26},"Mala Kamboj",{"name":45,"role":46,"phone":20,"phoneExt":20,"email":20},"Ambika Gupta, MDS Oral Medicine & Radiology","SUB_INVESTIGATOR",{"name":48,"role":46,"phone":20,"phoneExt":20,"email":20},"Rajender Kumar Sharma, MDS Periodontics",{"type":50,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100622282","role-of-subgingival-instrumentation-in-oral-lichen-planus-100622282",false,"NCT07381595","Role of Subgingival Instrumentation in Oral Lichen Planus","Impact of Subgingival Instrumentation on Clinical and Immunohistochemical Presentation of Oral Lichen Planus With Gingival Involvement","Inclusion criteria:\n\n* Clinically and histopathologically confirmed cases of OLP.\n* OLP predominantly involving the gingiva.\n* Consent obtained.\n\nExclusion criteria:\n\n* Cases which does not fulfil either clinical or histopathological criteria.\n* Unwilling to participate in the study.\n* Patients with recorded history of factors that might modify immune response (such as patient on corticosteroids or medically compromised patients or suffering from heart diseases).\n* Cases undergoing treatment of OLP within past 6 months.\n* Biopsies with inadequate or non-representative samples\n* Cases histopathologically diagnosed as Lichenoid Dysplasia or Oral Lichenoid Lesions.\n* Cases diagnosed with autoimmune disorders.","ALL","18 Years",{"count":61,"type":62},30,"ESTIMATED","INTERVENTIONAL",[65],"NA","The goal of this interventional study is to assess the clinical and histopathological changes in Oral Lichen Planus patients with gingival involvement pre and post subgingival instrumentation.\n\nObjective- Primary objective: To observe and evaluate the clinical signs and symptoms in Oral Lichen Planus with gingival involvement. Secondary objective: To observe and evaluate the Cluster of Differentiation (CD) 4+ and 8+T lymphocytes in Oral Lichen Planus with gingival involvement.\n\nStudy group: 30 cases of Oral Lichen Planus with gingival involvement",[9],[69,70,71,72],"Subgingival instrumentation","Immunohistochemistry","CD4 and CD8 lymphocytes","Clinical parameters","NOT_YET_RECRUITING","2026-02-04",{"date":76,"type":77},"2026-02-06","ACTUAL",{"date":79,"type":62},"2026-03-01",{"date":81,"type":62},"2028-12-31",{"name":5,"class":6},1]