[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100332739":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":19,"centralContacts":23,"locations":28,"responsibleParty":46,"collaborators":10,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":10,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":55,"minAge":56,"maxAge":10,"enrollmentInfo":57,"targetDuration":10,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":10,"overallStatus":30,"whyStopped":10,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},{"fullName":5,"class":6},"Washington University School of Medicine","OTHER",[8,11,13,15,17],{"label":9,"type":10,"description":10,"interventionNames":10},"Study A: Chronic >1 year",null,{"label":12,"type":10,"description":10,"interventionNames":10},"Study A: Acute \u003C1 year",{"label":14,"type":10,"description":10,"interventionNames":10},"Study A: Household Control",{"label":16,"type":10,"description":10,"interventionNames":10},"Study B: Newly Diagnosed \u003C6 months",{"label":18,"type":10,"description":10,"interventionNames":10},"Study B: Household Controls",[20],{"name":21,"affiliation":5,"role":22},"Lara Crock, MD PhD","PRINCIPAL_INVESTIGATOR",[24],{"name":21,"role":25,"phone":26,"phoneExt":10,"email":27},"CONTACT","314-546-3882","crockl@wustl.edu",[29],{"facility":5,"status":30,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"RECRUITING","St Louis","Missouri","63110","United States","US",{"type":37,"coordinates":38},"Point",[39,40],-90.19789,38.62727,{"lat":40,"lon":39},[43,45],{"name":44,"role":25,"phone":10,"phoneExt":10,"email":10},"Laura Crock, MD",{"name":44,"role":22,"phone":10,"phoneExt":10,"email":10},{"type":47,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100332739","role-of-the-gut-microbiome-in-complex-regional-pain-syndrome-100332739",false,"NCT03612193","Role of the Gut Microbiome in Complex Regional Pain Syndrome","Study A: Cross-sectional study\n\nInclusion criteria, cases:\n\n* Adults over the age of 18\n* Current (\\\u003C 1 year duration) or former (\\> 1 year) diagnosis of Complex Regional Pain Syndrome by the Budapest criteria\n* English as primary language\n* able to consent\n\nInclusion criteria, controls\n\n* Adults over age of 18\n* Cohabitant of person with current or former diagnosis of CRPS\n\nStudy B: Longitudinal Study\n\nInclusion criteria, cases:\n\n* Adults over the age of 18\n* Recent diagnosis (\\\u003C6 months) of Complex Regional Pain Syndrome by the Budapest criteria\n* English as primary language\n* able to consent\n\nInclusion criteria, controls\n\n* Adults over age of 18\n* Cohabitant of person with diagnosis of CRPS\n\nStudy A and B: Exclusion criteria, cases and controls:\n\n* Unwilling to participate in the study\n* Lives alone\n* Current use of probiotics and unwilling to stop for 1 week prior to stool sample\n* Pregnant or lactating\n* Vegan diet",true,"ALL","18 Years",{"count":58,"type":59},140,"ESTIMATED","OBSERVATIONAL","The objective of this prospective, observational study is to determine the association between the composition of the gut microbiota and the severity and persistence of Complex Regional Pain Syndrome symptoms (Study A). The objective of Study B, a longitudinal study of microbiota biomarkers of patients with newly diagnosed CRPS is to determine if the researchers can predict which patients are more likely to recover compared to those who do not. A secondary objective of both studies is to examine cognitive flexibility in relation to outcomes (study A and B).",[63],"Complex Regional Pain Syndromes","2025-11-03",{"date":66,"type":67},"2025-11-05","ACTUAL",{"date":69,"type":67},"2018-12-19",{"date":71,"type":59},"2027-07",{"name":5,"class":6},1]