[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633697":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":18,"locations":10,"responsibleParty":24,"collaborators":10,"id":26,"slug":27,"hasResults":28,"nctId":29,"briefTitle":30,"officialTitle":31,"acronym":32,"eligibilityCriteria":33,"healthyVolunteers":28,"sex":34,"minAge":35,"maxAge":10,"enrollmentInfo":36,"targetDuration":10,"studyType":39,"phases":40,"briefSummary":42,"conditions":43,"keywords":45,"overallStatus":49,"whyStopped":10,"lastUpdateSubmitDate":50,"lastUpdatePostDateStruct":51,"startDateStruct":54,"completionDateStruct":56,"leadSponsor":58,"locationsCount":10},{"fullName":5,"class":6},"Assistance Publique - Hôpitaux de Paris","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Patient",null,[12],"Other: collection of blood and stool\u002Fchyme and intestinal biopsy",[14],{"type":6,"name":15,"description":16,"armGroupLabels":17,"otherNames":10},"collection of blood and stool\u002Fchyme and intestinal biopsy","The only procedures added by the study are the collection of an additional volume of blood and stool\u002Fchyme during samples taken as part of routine care, as well as an intestinal biopsy",[9],[19],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},"Francesca Joly, MD","CONTACT","+33 1 40 87 53 32","francisca.joly@aphp.fr",{"type":25,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100633697","role-of-the-microbiota-in-intestinal-adaptation-during-short-bowel-syndrome-100633697",false,"NCT07530055","Role of the Microbiota in Intestinal Adaptation During Short Bowel Syndrome","Role of the Microbiota in Intestinal Adaptation During Short Bowel Syndrome: a Longitudinal Follow-up","AdMIR","Inclusion Criteria:\n\n* Age ≥18 years\n* Diagnosis of short bowel syndrome with a jejunostomy and a plan to restore jejuno-colic continuity within 3 months\n* Remaining post-duodenal small intestine (after the ligament of Treitz) \\\u003C 200 cm\n* Remaining colon \\> 14%\n* Remaining small intestine and colon are healthy (no residual inflammatory, post-radiation, or ischemic disease)\n* Patient enrolled in a social security system or entitled to coverage\n\nExclusion Criteria:\n\n* Pregnancy\n* Patient unable to provide consent:\n* Due to a disability preventing consent\n* Does not understand French\n* Patient deprived of liberty, or under legal protection (guardianship or curatorship)\n* Participation in another interventional study","ALL","18 Years",{"count":37,"type":38},15,"ESTIMATED","INTERVENTIONAL",[41],"NA","During the first years following intestinal resection, spontaneous physiological adaptations occur in patients with short bowel syndrome (SBS), allowing improvement of the absorptive capacity of the remaining intestine. This adaptation is particularly effective in SBS patients with the colon in continuity. The specific relationship between this intestinal adaptation and changes in the gut microbiota has not been studied in these patients. We hypothesize that there is a specific relationship between the microbiota and its metabolites and intestinal adaptive capacity, and that certain gut bacteria may promote this spontaneous adaptation.",[44],"Short Bowel Syndrome (SBS)",[46,47,48],"Short Bowel Syndrome","Intestinal Adaptation","Gastrointestinal Microbiome","NOT_YET_RECRUITING","2026-04-08",{"date":52,"type":53},"2026-04-15","ACTUAL",{"date":55,"type":38},"2026-04",{"date":57,"type":38},"2029-02",{"name":5,"class":6}]