[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100584978":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":21,"locations":10,"responsibleParty":31,"collaborators":10,"id":35,"slug":36,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":40,"acronym":10,"eligibilityCriteria":41,"healthyVolunteers":42,"sex":43,"minAge":44,"maxAge":45,"enrollmentInfo":46,"targetDuration":10,"studyType":49,"phases":10,"briefSummary":50,"conditions":51,"keywords":10,"overallStatus":53,"whyStopped":10,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":10},{"fullName":5,"class":6},"Assiut University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"cases with juvenile autoimmune hepatitis",null,"patients who are diagnosed physically, clinically, and histologically with juvenile autoimmune hepatitis",{"label":13,"type":10,"description":14,"interventionNames":10},"control group","children with near-normal liver biopsy",[16,19],{"name":17,"affiliation":5,"role":18},"Howadya Ismail Hassan El Sayed, PhD","STUDY_DIRECTOR",{"name":20,"affiliation":5,"role":18},"Moemen Mostafa Ahmed Hafez, PhD",[22,27],{"name":23,"role":24,"phone":25,"phoneExt":10,"email":26},"Mariam Mohamed Rashwan, bachelor's degree","CONTACT","+20 1158056572","Mariam.rashwan@aun.edu.eg",{"name":28,"role":24,"phone":29,"phoneExt":10,"email":30},"Shimaa Hassan Shaban, PhD","+20 1090651710","shimaahassan@aun.edu.eg",{"type":32,"investigatorFullName":33,"investigatorTitle":34,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Mariam Mohamed Rashwan Mohamed","Assistant lecturer","100584978","role-of-usp35-in-the-detection-of-ferroptosis-in-juvenile-autoimmune-hepatitis-100584978",false,"NCT06896383","Role of USP35 in the Detection of Ferroptosis in Juvenile Autoimmune Hepatitis","Role of USP35 in the Detection of Ferroptosis in Juvenile Autoimmune Hepatitis: an Immunohistochemical Study","Inclusion Criteria:\n\n* Patients aged between one day and 18 years (children)\n* patients diagnosed clinically and physically with juvenile autoimmune hepatitis including seronegative autoimmune hepatitis cases\n\nExclusion Criteria:\n\n1. Cases with inadequate tissue in the paraffin block\n2. Children with viral hepatitis\n3. patients above the age of 18 years old",true,"ALL","1 Day","18 Years",{"count":47,"type":48},60,"ESTIMATED","OBSERVATIONAL","1. To evaluate the immunohistochemical expression of USP35 in cases of juvenile autoimmune hepatitis and control cases.\n2. To correlate this with the level of necro-inflammation and extent of fibrosis using Massion's trichrome stain in cases of juvenile autoimmune hepatitis.",[52],"Autoimmune Hepatitis","NOT_YET_RECRUITING","2025-03-24",{"date":56,"type":57},"2025-03-26","ACTUAL",{"date":59,"type":48},"2025-11",{"date":61,"type":48},"2027-01",{"name":5,"class":6}]