[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100599175":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":33,"locations":38,"responsibleParty":55,"collaborators":11,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":61,"acronym":11,"eligibilityCriteria":62,"healthyVolunteers":59,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":11,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":11,"overallStatus":41,"whyStopped":11,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"West China Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Amino acid-derived lipids","EXPERIMENTAL",null,[13],"Drug: Amino acid-derived lipids",{"label":15,"type":16,"description":11,"interventionNames":17},"standard of care","ACTIVE_COMPARATOR",[18],"Behavioral: standard of care",[20,24],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":11},"DRUG","Amino acid-derived lipids are applied to the treatment area, once daily during radiotherapy.",[9],{"type":25,"name":15,"description":26,"armGroupLabels":27,"otherNames":11},"BEHAVIORAL","Standard of care",[15],[29],{"name":30,"affiliation":31,"role":32},"Xingchen Peng","Sichuan University West China Hospital","PRINCIPAL_INVESTIGATOR",[34],{"name":30,"role":35,"phone":36,"phoneExt":11,"email":37},"CONTACT","+8618980606753","pxx2014@163.com",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":11,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"West China Hospital, Sichuan University","RECRUITING","Chengdu","Sichuan","China","CN",{"type":47,"coordinates":48},"Point",[49,50],104.06667,30.66667,{"lat":50,"lon":49},[53],{"name":30,"role":35,"phone":54,"phoneExt":11,"email":37},"+86 18980606753",{"type":32,"investigatorFullName":30,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"professor","100599175","ros-scavenging-amino-acid-derived-lipids-for-the-prevention-and-treatment-of-radiation-dermatitis-in-patients-with-head-and-neck-cancer-100599175",false,"NCT07081074","ROS-scavenging Amino Acid-derived Lipids for the Prevention and Treatment of Radiation Dermatitis in Patients With Head and Neck Cancer","Inclusion Criteria:\n\n1. Patients with a pathological diagnosis of non-metastatic head and neck malignant tumors;\n2. Patients deemed suitable for high-dose radiotherapy, either as a primary treatment or as postoperative treatment following surgical resection.\n\nExclusion Criteria:\n\n1. Eastern Cooperative Oncology Group performance status of \\>2;\n2. Pre-existing skin rash, ulceration or open wound in the treatment area;\n3. Known allergy to trolamine or amino acid;\n4. Inflammatory or connective tissue disorder of the skin;\n5. History of head and neck radiotherapy.","ALL","18 Years","80 Years",{"count":67,"type":68},40,"ESTIMATED","INTERVENTIONAL",[71],"NA","Radiation dermatitis is a common complication in head and neck squamous cell carcinoma patients receiving radiotherapy. This study proposes an ROS-scavenging amino acid-based nanolipid to prevent oxidative skin damage. A multicenter randomized trial will evaluate its safety and efficacy in reducing dermatitis severity and improving treatment continuity.",[74],"Radiation Dermatitis","2026-04-14",{"date":77,"type":78},"2026-04-15","ACTUAL",{"date":80,"type":78},"2025-07-23",{"date":82,"type":68},"2026-12-23",{"name":5,"class":6},1]