[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100500475":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":44,"responsibleParty":61,"collaborators":26,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":66,"sex":72,"minAge":73,"maxAge":26,"enrollmentInfo":74,"targetDuration":26,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":47,"whyStopped":26,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Samsung Medical Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Routine stress testing","EXPERIMENTAL","In this group, the preselected functional stress testing (exercise electrocardiography, stress echocardiography, nuclear imaging, or stress cardiac magnetic resonance imaging) will be performed within three months (± 2 months) according to the practice pattern of each participating center.",[13],"Diagnostic Test: Non-invasive stress test",{"label":15,"type":16,"description":17,"interventionNames":18},"As-needed stress testing","ACTIVE_COMPARATOR","In this group, optimal medical treatment will be performed by current guidelines without further testing. A stress test will be performed only when new symptoms (exertional chest pain or dyspnea) occur that may clinically suggest significant coronary artery disease.",[19],"Diagnostic Test: Medical treatment without further testing",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIAGNOSTIC_TEST","Non-invasive stress test","Nuclear imaging, stress echocardiography, exercise electrocardiography, stress cardiac magnetic resonance imaging",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Medical treatment without further testing","Optimal medical treatment for primary prevention.",[15],[32],{"name":33,"affiliation":5,"role":34},"Seung-Hyuk Choi, MD","PRINCIPAL_INVESTIGATOR",[36,40],{"name":33,"role":37,"phone":38,"phoneExt":26,"email":39},"CONTACT","82-2-3410-3419","sh1214.choi@samsung.com",{"name":41,"role":37,"phone":42,"phoneExt":26,"email":43},"Ki Hong Choi","82-2-3410-6653","cardiokh@gmail.com",[45],{"facility":46,"status":47,"city":48,"state":26,"zip":49,"country":50,"countryCode":26,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"SamsungMedicalCenter","RECRUITING","Seoul","06351","South Korea",{"type":52,"coordinates":53},"Point",[54,55],126.9784,37.566,{"lat":55,"lon":54},[58],{"name":59,"role":37,"phone":60,"phoneExt":26,"email":26},"Seunghyuk Choi, PhMD","82-2-3410-3437",{"type":34,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Seung-Hyuk Choi","Professor","100500475","routine-versus-as-needed-stress-testing-in-asymptomatic-patients-with-high-risk-coronary-calcium-100500475",false,"NCT05796739","Routine Versus As-Needed Stress Testing in Asymptomatic Patients With High-Risk Coronary Calcium","SMart Angioplasty Research Team-Pragmatic Randomized Trial for Comparing Routine Versus As-Needed EXercise or Pharmacologic Stress Testing in Asymptomatic Patients With High-Risk Coronary CalciuM (SMART-EXAM)","SMART-EXAM","Inclusion Criteria:\n\n* Subject must be at least 19 years of age. ② Asymptomatic patients with high-risk coronary calcium (Agatston Score ≥ 400)\n\nExclusion Criteria:\n\n* Documentation of objective evidence of inducible ischemia before enrollment\n\n  * Presence of significant coronary artery stenosis (≥ 70% diameter stenosis) confirmed by coronary angiography or coronary computed tomography angiography before enrollment\n\n    * History of coronary revascularization procedure ④ Pregnancy or breast feeding ⑤ Non-cardiac co-morbid conditions are present with life expectancy \\\u003C1 year or that may result in protocol non-compliance (per site investigator's medical judgment) ⑥ Unwillingness or inability to comply with the procedures described in this protocol.","ALL","19 Years",{"count":75,"type":76},3000,"ESTIMATED","INTERVENTIONAL",[79],"NA","The purpose of the SMART-EXAM (SMart Angioplasty Research Team-Pragmatic Randomized Trial for Comparing Routine versus As-Needed EXercise or Pharmacologic Stress Testing in Asymptomatic Patients with High-Risk Coronary CalciuM) trial is to compare the major adverse cardiovascular events between routine stress testing and as-needed stress testing in asymptomatic patients with high-risk coronary calcium (Agatston Score ≥ 400) without proven ASCVD.",[82],"Coronary Atherosclerosis Due to Calcified Coronary Lesion",[23,84,85],"Coronary calcification","Agatston score","2025-01-12",{"date":88,"type":89},"2025-01-14","ACTUAL",{"date":91,"type":89},"2023-07-03",{"date":93,"type":76},"2029-12-31",{"name":5,"class":6},1]