[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586573":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":39,"responsibleParty":57,"collaborators":25,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":63,"acronym":25,"eligibilityCriteria":64,"healthyVolunteers":61,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":25,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":79,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Universidade Federal Fluminense","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Royal Jelly Group","EXPERIMENTAL","Participants will receive 2 capsules per day, providing the dosage of 300mg of royal jelly for 2 months (8 weeks).",[13],"Dietary Supplement: Royal Jelly",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo Group","PLACEBO_COMPARATOR","The placebo group will receive 2 capsules per day (containing microcrystalline cellulose and magnesium stearate in colored gelatin capsules capable of masking the appearance of the internal content), at the same time for 2 months.",[19],"Dietary Supplement: Placebo",[21,26],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"DIETARY_SUPPLEMENT","Royal Jelly",[9],null,{"type":22,"name":27,"description":17,"armGroupLabels":28,"otherNames":25},"Placebo",[15],[30],{"name":31,"affiliation":5,"role":32},"Ludmila Cardozo, PhD","PRINCIPAL_INVESTIGATOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":25,"email":38},"Denise mafra, PhD","CONTACT","+5521985683003","dmafra30@gmail.com",[40],{"facility":41,"status":42,"city":43,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Denise Mafra","RECRUITING","Rio de Janeiro","22260050","Brazil","BR",{"type":48,"coordinates":49},"Point",[50,51],-43.18223,-22.90642,{"lat":51,"lon":50},[54],{"name":31,"role":36,"phone":55,"phoneExt":25,"email":56},"+5521987333185","ludmila.cardozo@gmail.com",{"type":58,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100586573","royal-jelly-as-a-strategy-to-modulate-inflammation-and-oxidative-stress-in-patients-with-systemic-arterial-hypertension-100586573",false,"NCT06917131","Royal Jelly as a Strategy to Modulate Inflammation and Oxidative Stress in Patients With Systemic Arterial Hypertension","Inclusion Criteria:\n\n* Diagnosis of stage 1 hypertension\n* Regular treatment for more than 6 months\n* No changes in medication doses during the last 3 months\n\nExclusion Criteria:\n\n* Autoimmune diseases\n* Infectious diseases\n* Diabetes\n* Chronic kidney disease\n* Liver disease\n* Cancer\n* AIDS\n* Pregnant women\n* Use of catabolic drugs or antibiotics\n* Use of antioxidant vitamin supplements, prebiotics, probiotics, or synbiotics\n* Habitual intake of royal jelly\n* Allergy to bee stings\n* Acute myocardial infarction (AMI)\n* Stroke (CVA)","ALL","18 Years","75 Years",{"count":69,"type":70},34,"ESTIMATED","INTERVENTIONAL",[73],"NA","The study aims to evaluate the effect of the royal jelly on inflammation and oxidative stress in participants with systemic arterial hypertension. A longitudinal double-blind randomized clinical trial will be carried out, involving hypertensive participants for two months.",[76,77,78],"Hypertension","Cardiovascular Diseases (CVD)","Inflammation",[80,81,76,82],"royal jelly","inflammation","cardiovascular diseases","2026-05-14",{"date":85,"type":86},"2026-05-19","ACTUAL",{"date":88,"type":86},"2024-09-18",{"date":90,"type":70},"2026-12-10",{"name":5,"class":6},1]