[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100429062":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":35,"centralContacts":40,"locations":49,"responsibleParty":92,"collaborators":26,"id":94,"slug":95,"hasResults":96,"nctId":97,"briefTitle":98,"officialTitle":99,"acronym":100,"eligibilityCriteria":101,"healthyVolunteers":96,"sex":102,"minAge":103,"maxAge":104,"enrollmentInfo":105,"targetDuration":26,"studyType":108,"phases":109,"briefSummary":111,"conditions":112,"keywords":114,"overallStatus":77,"whyStopped":26,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":129},{"fullName":5,"class":6},"Centre Hospitalier Universitaire de Saint Etienne","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"rTMS active and active mirror-based therapy using virtual reality","EXPERIMENTAL","The patient will have an amount of 4 sessions (S3, S5, S7 and S9) for 1.5 months: 1 session every 2 weeks. The patient will receive rTMS active and active mirror-based therapy using virtual reality.",[13,14],"Other: Repetitive transcranial magnetic stimulation (rTMS)","Other: Mirror therapy using virtual reality",{"label":16,"type":17,"description":18,"interventionNames":19},"rTMS active and sham mirror-based therapy using virtual reality","SHAM_COMPARATOR","The patient will have an amount of 4 sessions (S3, S5, S7 and S9) for 1.5 months: 1 session every 2 weeks. The patient will receive rTMS active and sham mirror-based therapy using virtual reality.",[13,20],"Other: Mirror therapy using sham mirror",[22,27,31],{"type":6,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"Repetitive transcranial magnetic stimulation (rTMS)","20 minutes of high frequency (20Hz) rTMS.",[9,16],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Mirror therapy using virtual reality","active mirror-based therapy",[9],{"type":6,"name":32,"description":33,"armGroupLabels":34,"otherNames":26},"Mirror therapy using sham mirror","20 minutes of sham mirror-based therapy",[16],[36],{"name":37,"affiliation":38,"role":39},"Roland Peyron, MDPHD","CENTRE HOSPITALIER DE SAINT-ETIENNE","PRINCIPAL_INVESTIGATOR",[41,46],{"name":37,"role":42,"phone":43,"phoneExt":44,"email":45},"CONTACT","(0)477825684","+33","roland.peyron@univ-st-etienne.fr",{"name":47,"role":42,"phone":26,"phoneExt":26,"email":48},"Beatrice DEYGAS, CRA","beatrice.deygas@chu-st-etienne.fr",[50,75],{"facility":51,"status":52,"city":53,"state":26,"zip":54,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"Hôpital Neurologique Pierre Wertheimer","NOT_YET_RECRUITING","Bron","69500","France","FR",{"type":58,"coordinates":59},"Point",[60,61],4.91303,45.73865,{"lat":61,"lon":60},[64,68,70,73],{"name":65,"role":42,"phone":66,"phoneExt":44,"email":67},"Luis Garcia-Larrea, MD","0)472118866","luis-jose.garcia-larrea@chu-lyon.fr",{"name":69,"role":39,"phone":26,"phoneExt":26,"email":26},"Patrick MERTENS, MD PhD",{"name":71,"role":72,"phone":26,"phoneExt":26,"email":26},"Nathalie ANDRE-OBADIA, MD","SUB_INVESTIGATOR",{"name":74,"role":72,"phone":26,"phoneExt":26,"email":26},"Luis GARCIA- LARREA, MD",{"facility":76,"status":77,"city":78,"state":26,"zip":79,"country":55,"countryCode":56,"cosmosGeoPoint":80,"geoPoint":84,"contacts":85},"Centre Hospitalier Universitaire de Saint-Etienne","RECRUITING","Saint-Etienne","42055",{"type":58,"coordinates":81},[82,83],4.39,45.43389,{"lat":83,"lon":82},[86,89,91],{"name":87,"role":42,"phone":43,"phoneExt":44,"email":88},"Roland PEYRON, MD PHD","roland.peyron@chu-st-etienne.fr",{"name":90,"role":72,"phone":26,"phoneExt":26,"email":26},"Christelle Créac'h, MD",{"name":87,"role":39,"phone":26,"phoneExt":26,"email":26},{"type":93,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100429062","rtms-efficacy-coupled-with-mirror-therapy-100429062",false,"NCT04867187","rTMS Efficacy Coupled With Mirror Therapy","Clinical Study of Repetitive Transcranial Magnetic Stimulation (RTMS) Efficacy Coupled With Mirror Therapy for Neuropathic Pain Relief","STIRM","Inclusion Criteria:\n\n* Clinical symptoms typical of neuropathic pain\n* Refractory to drug therapies\n* Lasting for at least 6 months, with a moderate to severe pain intensity (≥4\u002F10 on Visual Analog Scale, VAS) and a stable pain treatment since 1month at least\n* Having right to health benefits\n\nExclusion Criteria:\n\n* Ferromagnetic components and implanted microprocessors (i.e. cochlear implants)\n* Drug-resistant or active epilepsy, pacemaker, pregnancy, ongoing depression or personality troubles, and ongoing opioid treatment.\n* Any other contraindications to MRI scanner (e.g., claustrophobia, etc.).","ALL","18 Years","85 Years",{"count":106,"type":107},64,"ESTIMATED","INTERVENTIONAL",[110],"NA","Neuropathic pain is particularly difficult to treat with classic first-line drugs. Neuromodulation techniques using repetitive transcranial magnetic stimulation (rTMS) are useful alternative, but there is a need to improve their analgesic effect.Virtual reality mirror therapy has shown the capacity to alleviate pain and may be easily coupled with rTMS.The present project will investigate in individuals with neuropathic pain the effects of the rTMS coupled with virtual reality mirror therapy.",[113],"Neuropathic Pain",[115,116,117,118,119],"transcranial magnetic stimulation","virtual reality","mirror therapy","brain networks","predictive model","2026-05-05",{"date":122,"type":123},"2026-05-08","ACTUAL",{"date":125,"type":123},"2022-10-27",{"date":127,"type":107},"2027-04",{"name":5,"class":6},2]