[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597895":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":41,"responsibleParty":58,"collaborators":26,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":26,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":69,"maxAge":26,"enrollmentInfo":70,"targetDuration":26,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":44,"whyStopped":26,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"General Hospital of Ningxia Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"General anesthesia group(NCB Group)","ACTIVE_COMPARATOR","Conventional general anesthesia was adopted, and laryngeal mask general anesthesia was only administered to the patient.",[13],"Procedure: Simple general anesthesia",{"label":15,"type":16,"description":17,"interventionNames":18},"Sacral canal block + General anesthesia group (CB group)","EXPERIMENTAL","Thirty minutes before the start of the operation, 30ML of the pre-prepared 0.375% ropivacaine was injected into the sacral canal under ultrasound guidance, and the diffusion of the local anesthetic in the sacral canal could be observed.",[19],"Procedure: Sacral canal block combined with general anesthesia",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Sacral canal block combined with general anesthesia","Sacral canal block: The patient lies on their side, with the back perpendicular to the edge of the operating table. The knee joints of the lower limbs are flexed, the thighs are close to the abdomen, and the waist is arched backward as much as possible, resembling a \"shrimp\" shape. The space between the sacrum and coccyx of the patient (sacral hiatus) is fully exposed. By using a low-frequency probe (such as 2-5 MHZ), the strong echo of the sacrum, the low echo of the sacral canal, and the echo of the surrounding soft tissues can be clearly seen. At the located sacral hiatus, hold the puncture needle and slowly insert it perpendicularly to the skin. When the puncture needle passes through the sacrococcygeal ligament, there will be a distinct \"breakthrough sensation\", which indicates that the puncture needle has entered the sacral canal. The general depth of needle insertion is about 2 to 3cm. However, the specific depth varies depending on factors such as the patient's body type.",[15],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Simple general anesthesia","General anesthesia: Midazolam (0.2mg\u002Fkg), sufentanil (0.2-0.4μg\u002Fkg), etomidate (0.15-0.3 mg\u002Fkg), and rocuronium (0.6 mg\u002Fkg) were induced. After the patient's muscles were completely relaxed, a laryngeal mask was placed. Connect the anesthesia machine and set the ventilator parameters: Vol.Mode, tidal volume 6-8ml\u002Fkg, frequency 10-14 times \u002Fmin, inhalation-exhalation ratio 1:2, and maintain EtCO2 at 35-45mmHg during the operation. Propofol (4-12mg\u002Fkg\u002Fh) and remifentanil (0.05-2ug\u002Fkg\u002Fmin) were maintained. According to the operation course, rocuronium (0.15mg\u002Fkg) and sevoflurane inhalation (1% - 7%) could be administered at a single time. Anesthesiologists adjust the drug infusion rate based on the patient's hemodynamic indicators SBP, MAP, HR and clinical experience. When HR was less than 45 times \u002Fmin during the operation, atropine was intravenously injected (0.25-0.5mg per time). When MAP is less than 55mmHg and lasts for more than 3 minutes, ephedrine (6-12mg each time) is given.",[9],[32,37],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Xinli Ni, MD","CONTACT","13909586966","xinlini6@nyfy.com.cn",{"name":38,"role":34,"phone":39,"phoneExt":26,"email":40},"Wenxuan Ma","18295009975","769462442@qq.com",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":26,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"General hospital of Ningxia medical university","RECRUITING","Yinchuan","Ningxia","China","CN",{"type":50,"coordinates":51},"Point",[52,53],106.27306,38.46806,{"lat":53,"lon":52},[56],{"name":33,"role":34,"phone":57,"phoneExt":26,"email":36},"86-0951-6743252",{"type":59,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100597895","sacral-canal-block-for-hip-replacement-the-efficacy-and-safety-of-controlled-intraoperative-hypotension-100597895",false,"NCT07064434","Sacral Canal Block for Hip Replacement the Efficacy and Safety of Controlled Intraoperative Hypotension","Sacral Canal Block for Hip Replacement the Efficacy and Safety of Controlled Intraoperative Hypotension:a Single-center, Prospective, Randomized Controlled Study","Inclusion Criteria:\n\n1. Over 45 years old;\n2. ASA Grade II - III;\n3. BMI 18-35kg\u002F㎡;\n4. Agree to participate in this study and sign the informed consent form.\n\nExclusion Criteria:\n\n1. Those who refuse to participate in the experiment;\n2. Those who suffer from language or hearing impairments and are unable to communicate;\n3. Those with contraindications for sacral canal block.",true,"ALL","45 Years",{"count":71,"type":72},80,"ESTIMATED","INTERVENTIONAL",[75],"NA","To observe the efficacy and safety of sacral canal block in controlled blood pressure reduction during hip replacement in the elderly, and to provide a better option for controlled blood pressure reduction during clinical hip surgery.",[78],"Postoperative Pain",[80,81,82],"Sacral canal block","Hip replacement","Postoperative rehabilitation","2025-07-03",{"date":85,"type":86},"2025-07-14","ACTUAL",{"date":88,"type":86},"2024-11-01",{"date":90,"type":72},"2025-10-30",{"name":5,"class":6},1]