[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100587327":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":32,"responsibleParty":50,"collaborators":52,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":57,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":18,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":76,"overallStatus":81,"whyStopped":18,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"St. John's Research Institute","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention Arm- Cerebral Oximetry + Treatment Guideline","EXPERIMENTAL","Neonates who are ventilated in the NICU, in addition to standard care, will be monitored by cerebral oximetry. If the value falls below a certain threshold, the treatment guideline will be followed and corrective interventions undertaken.",[13],"Other: Intervention Arm- Cerebral Oximetry + Treatment Guideline",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Arm- standard care","NO_INTERVENTION","Neonates who are ventilated in the NICU will receive standard care only.",null,[20],{"type":6,"name":9,"description":21,"armGroupLabels":22,"otherNames":23},"if the cerebral oximeter shows low values, a pre designed treatment guideline will be followed and corrective actions taken.",[9],[24],"NIRS",[26],{"name":27,"role":28,"phone":29,"phoneExt":30,"email":31},"saudamini Nesargi, Dr.","CONTACT","9243472262","91","saudamini_nesargi@yahoo.com",[33],{"facility":34,"status":18,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"St. jOhn's Medical college & Hospital","Bengaluru","Karnataka","560034","India","IN",{"type":41,"coordinates":42},"Point",[43,44],77.59369,12.97194,{"lat":44,"lon":43},[47],{"name":48,"role":28,"phone":49,"phoneExt":18,"email":18},"Saudamini Nesargi, Dr.","919243472262",{"type":51,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR",[53],{"name":54,"class":6},"Rigshospitalet, Denmark","100587327","safeboosc-iiiv---does-cerebral-oximetry-monitoring-affect-renal-outcomes-100587327",false,"NCT06926946","SafeBoosC-IIIv - Does Cerebral Oximetry Monitoring Affect Renal Outcomes","The Effects of Treatment Guided by Cerebral Oximetry Monitoring on Renal Outcomes in Invasively Mechanically Ventilated Neonates: an Ancillary Study of the SafeBoosC-IIIv Trial","SBIIIvR","Inclusion Criteria:\n\n* \\> 28 weeks of gestation Invasively ventilated\n\nExclusion Criteria:\n\n* major anomalies","ALL","1 Day","28 Days",{"count":67,"type":68},1000,"ESTIMATED","INTERVENTIONAL",[71],"NA","Cerebral oximetry monitoring allows clinicians to optimize blood flow to the brain and oxygenation using the SafeBoosC treatment guideline. The guideline's interventions aims to stabilize blood pressure and oxygen levels.\n\nAs low blood pressure is a risk factor for the development of kidney injury, normalizing blood pressure may decrease the incidence of kidney injury in new-borns who are on ventilator.",[74,75],"Acute Renal Failure","Neonatal Morbidity",[77,24,78,79,80],"Cerebral oximetry","Neonate","Ventilated","Kidney injury","NOT_YET_RECRUITING","2025-07-17",{"date":84,"type":85},"2025-07-23","ACTUAL",{"date":87,"type":68},"2025-07-31",{"date":89,"type":68},"2027-09-15",{"name":5,"class":6},1]