[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100570084":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":26,"responsibleParty":44,"collaborators":26,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":50,"sex":55,"minAge":56,"maxAge":26,"enrollmentInfo":57,"targetDuration":26,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":71,"whyStopped":26,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":26},{"fullName":5,"class":6},"The First Hospital of Jilin University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"RIC","ACTIVE_COMPARATOR","Remote ischemic conditioning (RIC) is induced by 5 cycles of 5 min of bilateral upper limbs ischemia followed by 5 min reperfusion. Limb ischemia was induced by inflation of a blood pressure cuff to 200 mmHg. RIC will be conducted twice daily for 6 consecutive days after enrollment.",[13],"Device: Remote ischemic conditioning",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham RIC","PLACEBO_COMPARATOR","Sham remote ischemic conditioning (RIC) is induced by 5 cycles of 5 min of bilateral upper limbs ischemia followed by 5 min reperfusion. Limb ischemia was induced by inflation of a blood pressure cuff to 60 mmHg. Sham RIC will be conducted twice daily for 6 consecutive days after enrollment.",[19],"Device: Sham remote ischemic conditioning",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Remote ischemic conditioning","Remote ischemic conditioning: Remote ischemic conditioning (RIC) is induced by 5 cycles of 5 min of bilateral upper limbs ischemia followed by 5 min reperfusion. Limb ischemia was induced by inflations of a blood pressure cuff to 200 mmHg.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sham remote ischemic conditioning","Sham remote ischemic conditioning (RIC) is induced by 5 cycles of 5 min of bilateral upper limbs ischemia followed by 5 min reperfusion. Limb ischemia was induced by inflations of a blood pressure cuff to 60 mmHg.",[15],[32],{"name":33,"affiliation":34,"role":35},"Yi Yang, MD, PhD","Neuroscience Center, Department of Neurology, The First Hospital of Jilin University","STUDY_CHAIR",[37,41],{"name":33,"role":38,"phone":39,"phoneExt":26,"email":40},"CONTACT","0086-13756661217","doctor_yangyi@163.com",{"name":42,"role":38,"phone":26,"phoneExt":26,"email":43},"Zhenni Guo, MD, PhD","zhen1ni2@163.com",{"type":45,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","Yi Yang","Vice president of The First Hospital of Jilin University","100570084","safety-and-efficacy-of-remote-ischemic-conditioning-in-patients-with-chronic-internal-carotid-artery-occlusion-receiving-hybird-surgery-a-pilot-randomized-controlled-trial-100570084",false,"NCT06702644","Safety and Efficacy of Remote Ischemic Conditioning in Patients with Chronic Internal Carotid Artery Occlusion Receiving Hybird Surgery: a Pilot, Randomized Controlled Trial","SERIC-HS","Inclusion Criteria:\n\n* Age≥18 years, regardless of sex\n* Patients with chronic carotid artery occlusion who are going to undergo hybird surgery\n* Can cooperate with and complete brain magnetic resonance imaging (MRI) examination\n* Signed and dated informed consent is obtained\n\nExclusion Criteria:\n\n* Hemorrhagic stroke\n* Severe cardiac dysfunction or arrhythmia\n* Uncontrolled hypertension (defined as systolic blood pressure ≥ 180 mmHg or diastolic blood pressure ≥ 110 mmHg, despite medication taken at enrollment)\n* Severe hepatic and renal dysfunction (defined as aspartate aminotransferase (AST) or alanine aminotransferase (ALT) ≥3 times higher than the upper limit of the normal range, creatinine \\>265umol\u002Fl (3mg\u002Fdl))\n* The patients who have the contraindication of remote ischemic conditioning treatment, such as severe soft tissue injury, fracture or vascular injury in the upper limb. Acute or subacute venous thrombosis, arterial occlusive disease, subclavian steal syndrome, etc.\n* Pregnant or lactating women\n* He\u002FShe is participating in other clinical research or has participated in other clinical research or has participated in this study within 3 months prior to admission\n* Other conditions that the researchers think are not suitable for the group","ALL","18 Years",{"count":58,"type":59},60,"ESTIMATED","INTERVENTIONAL",[62],"NA","The purpose of this study is to explore the safety and efficacy of remote ischemic conditioning in patients with internal carotid artery occlusion receiving hybird surgery.",[65],"Carotid Artery Occlusion",[9,67,68,69,70],"remote ischemic conditioning","carotid artery occlusion","hybird surgery","interventional surgery","NOT_YET_RECRUITING","2024-11-25",{"date":74,"type":75},"2024-11-26","ACTUAL",{"date":77,"type":59},"2024-12-01",{"date":79,"type":59},"2027-03-31",{"name":46,"class":6}]