[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100612794":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":20,"locations":26,"responsibleParty":63,"collaborators":10,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":73,"sex":74,"minAge":75,"maxAge":10,"enrollmentInfo":76,"targetDuration":79,"studyType":80,"phases":10,"briefSummary":81,"conditions":82,"keywords":84,"overallStatus":28,"whyStopped":10,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"machineMD AG","INDUSTRY",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Healthy volunteers",null,"Healthy volunteers, meaning no known ophthalmological, neurological or vestibular disease.\n\nThe healthy volunteers are within the age groups: 3-6, 7-9, 10-12, 13-17, 18-29, 30-39, 40-49, 50-59, 60-69, 70-79, \\>80.",{"label":13,"type":10,"description":14,"interventionNames":10},"Neurological and ophthalmic patients","Patients with ophthalmological diseases (e.g. strabismus, cataract, macular degeneration, central artery syndrome) Patients with neurological diseases (e.g. Small-Vessel White-Matter Disease, cerebellar ataxia, stroke, downbeat-nystagmus, vascular dementia, multiple sclerosis, M. Parkinson, M. Niemann-Pick type C, M. Alzheimer, galactosemia, schizophrenia, etc).",[16],{"name":17,"affiliation":18,"role":19},"Tatiana Bremova-Ertl, MD, PhD","Inselspital","PRINCIPAL_INVESTIGATOR",[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Pia Massatsch, PhD","CONTACT","+41 79 607 61 37","pia.massatsch@machinemd.com",[27,42,52],{"facility":5,"status":28,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"RECRUITING","Bern","Canton of Bern","3008","Switzerland","CH",{"type":35,"coordinates":36},"Point",[37,38],7.44744,46.94809,{"lat":38,"lon":37},[41],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},{"facility":43,"status":28,"city":29,"state":30,"zip":44,"country":32,"countryCode":33,"cosmosGeoPoint":45,"geoPoint":47,"contacts":48},"Inselspital, Bern university hospital","3010",{"type":35,"coordinates":46},[37,38],{"lat":38,"lon":37},[49],{"name":17,"role":23,"phone":50,"phoneExt":10,"email":51},"+41 31 632 70 00","tatiana.bremova-ertl@insel.ch",{"facility":53,"status":28,"city":29,"state":30,"zip":54,"country":32,"countryCode":33,"cosmosGeoPoint":55,"geoPoint":57,"contacts":58},"Onovis Augenpraxis","3011",{"type":35,"coordinates":56},[37,38],{"lat":38,"lon":37},[59],{"name":60,"role":23,"phone":61,"phoneExt":10,"email":62},"Moritz Feil, Dr med","+41 31 311 15 55","moritz.feil@hin.ch",{"type":64,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100612794","safety-and-normative-data-with-neos-100612794",false,"NCT07258212","Safety and Normative Data With Neos™","Safety and Normative Data With Neos™, in Healthy Volunteers, Children and Patient Populations With Ophthalmological or Neurological Disease","neos-SNOW","Inclusion Criteria Healthy Volunteers:\n\n* Age \\> 3\n* Informed consent by participant and\u002For legal representative documented per signature\n* Snellen visual acuity ≥ +0.1 LogMAR, with correction, on both eyes\n* Refractive error between -10 and +5 diopters, on both eyes\n\nExclusion Criteria Healthy Volunteers:\n\n* Known ophthalmological, neurological or vestibular disease\n* Current medication\u002Fdrugs that could potentially influence performance in ocular motor tasks and\u002For compliance in the judgement of the investigator (e.g. benzodiazepines, alcohol, or stimulants)\n* Stimulative medication (e.g. with Ritalin®)\n* Known substance abuse\n\nInclusion Criteria Patients:\n\n* Age \\> 3\n* Informed consent by participant and\u002For legal representative, designated trusted person or next of kin, documented per signature\n* Refractive error between -10 and +5 diopters, on both eyes\n* Known ophthalmological or neurological disease\n\nExclusion Criteria Patients:\n\n* Visual acuity in one or both eyes \\\u003C +1.3 LogMAR\n* Incapacity to understand and comply with the examination in the opinion of the investigator (e.g. due to very advanced dementia, with failure to comply with easy experimental instructions and tasks)\n* Known substance abuse",true,"ALL","3 Years",{"count":77,"type":78},200,"ESTIMATED","1 Day","OBSERVATIONAL","The goal of this clinical study is to collect standard data for the medical device neos™.\n\nneos™ is a system that shows images and measures the resulting eye movements and pupil size.\n\nCollecting standard data involves three steps. First it is checked if neos™ eye-tracking works well. Eye-tracking means recording where a person is looking. After that it is checked if participants look at the images shown in neos™ as planned. Finally the eye movements and the pupil size are measured. This is done in healthy volunteers including children and persons with eye and brain problems.\n\nParticipants in the study will wear a virtual reality headset. The screens in the headset will show different images. Cameras in the headset will record eye movements and pupil size. This will take about 15 minutes. During these 15 minutes the investigator looks at the following behaviors of the participants eyes:\n\n* Where are the eyes looking\n* How do the pupils react to light and darkness\n* How do the eyes move\n* How much can the participant see from the corner of their eyes\n* How well are the eyes working together",[83],"Neuro-Ophthalmology",[85,86,87,88,89,90,91,92,93,94],"Virtual reality","Visual field","Ocular alignment","Afferent pupillary function","Efferent pupillary function","Smooth pursuit","Saccades","Gaze holding","Fusional amplitude","Normative data","2025-11-27",{"date":97,"type":98},"2025-12-02","ACTUAL",{"date":100,"type":98},"2024-03-07",{"date":102,"type":78},"2026-06",{"name":5,"class":6},3]