[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607555":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":10,"centralContacts":25,"locations":31,"responsibleParty":48,"collaborators":10,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":52,"sex":58,"minAge":59,"maxAge":10,"enrollmentInfo":60,"targetDuration":10,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":10,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":76},{"fullName":5,"class":6},"Peking Union Medical College Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients clinically suspected with acute PE",null,"This study will enroll adult patients (\\>18 years) with clinically suspected or confirmed acute pulmonary embolism (PE) presenting with acute respiratory failure, who either undergo computed tomography pulmonary angiography (CTPA) within 24 hours or are scheduled for CTPA within the next 24 hours. Eligible participants need to have an indwelling central venous catheter (internal jugular or subclavian vein) or a peripheral forearm venous line, with no restrictions on gender.",[13,14],"Diagnostic Test: Saline contrast Electrical Impedance Tomography method","Diagnostic Test: Computed Tomography Pulmonary Angiography (CTPA)",[16,21],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":10},"DIAGNOSTIC_TEST","Saline contrast Electrical Impedance Tomography method","This study will enroll patients with clinically suspected or confirmed acute pulmonary embolism (PE) presenting with acute respiratory failure, who undergo electrical impedance tomography (EIT) with saline contrast within 24 hours before or after computed tomography pulmonary angiography (CTPA). The EIT procedure is performed as follows:\n\n1. Breath-Hold Maneuver: (1)Spontaneous breathing patients: Supine position, instructed to hold expiration for ≥8 seconds. (2)Mechanically ventilated patients: Expiratory hold (\\>8 sec) achieved via ventilator; deeper sedation will be applied when feasible to prolong breath-hold.\n2. Venous Access: (1)Preferred: Central venous catheter (internal jugular or subclavian vein).(2)Alternative: Peripheral forearm vein (preferably the median cubital vein).\n3. Contrast Administration:(1)Central venous route: 10 mL of 10% NaCl.(2)Peripheral venous route: 15 mL of 5% NaHCO₃.",[9],{"type":17,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"Computed Tomography Pulmonary Angiography (CTPA)","Patients who meet the inclusion criteria will undergo CTPA examination using conventional clinical diagnostic methods.",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},"Huaiwu He","CONTACT","01069152301","tjmuhhw@163.com",[32],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences","RECRUITING","Beijing","Beijing Municipality","100730","China","CN",{"type":41,"coordinates":42},"Point",[43,44],116.39723,39.9075,{"lat":44,"lon":43},[47],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},{"type":49,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100607555","saline-contrast-electrical-impedance-tomography-method-for-diagnosis-of-acute-pulmonary-embolism-100607555",false,"NCT07190079","Saline Contrast Electrical Impedance Tomography Method for Diagnosis of Acute Pulmonary Embolism","A Multicenter Comparative Study of Saline Contrast Electrical Impedance Tomography Method Versus CTPA in the Diagnosis of Acute Pulmonary Embolism","ECTPED","Inclusion Criteria:\n\n1. Patients with clinically suspected or confirmed acute pulmonary embolism (PE) presenting with acute respiratory failure;\n2. Availability of CTPA results within 24 hours or scheduled to undergo CTPA within the next 24 hours;\n3. Age \\>18 years; no gender restrictions;\n4. Presence of central venous access (internal jugular or subclavian vein) or peripheral forearm venous access;\n5. Willingness to participate with signed informed consent from either the patient or legal guardian.\n\nExclusion Criteria:\n\n1. Pregnancy or lactation;\n2. Relative contraindications to EIT examination (e.g., chest wall wounds at electrode belt placement site, presence of pacemakers);\n3. Severe hypernatremia (serum sodium \\>155 mmol\u002FL);\n4. Inability to maintain expiratory breath-hold for ≥8 seconds;\n5. BMI \\>50 or severe thoracic deformities;\n6. Current extracorporeal membrane oxygenation (ECMO) therapy.","ALL","18 Years",{"count":61,"type":62},343,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to compare the consistency of saline contrast Electrical Impedance Tomography(EIT) method and Computed Tomography Pulmonary Angiography (CTPA) in diagnosing acute pulmonary embolism. The main question it aims to answer is:\n\nCan bedside saline contrast EIT method be used for the diagnosis of acute pulmonary embolism? The participants will undergo saline contrast EIT and CTPA examinations successively within 24 hours.",[66],"Acute Pulmonary Embolism","2025-09-28",{"date":69,"type":70},"2025-10-02","ACTUAL",{"date":72,"type":70},"2025-09-24",{"date":74,"type":62},"2027-09-15",{"name":5,"class":6},1]