[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608742":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":12,"locations":18,"responsibleParty":34,"collaborators":7,"id":36,"slug":37,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":40,"acronym":7,"eligibilityCriteria":41,"healthyVolunteers":42,"sex":43,"minAge":44,"maxAge":7,"enrollmentInfo":45,"targetDuration":7,"studyType":48,"phases":7,"briefSummary":49,"conditions":50,"keywords":56,"overallStatus":21,"whyStopped":7,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":67},{"fullName":5,"class":6},"RenJi Hospital","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"nothing","This is an observational study.",[13],{"name":14,"role":15,"phone":16,"phoneExt":7,"email":17},"融 黄, Ph.D","CONTACT","+862168383816","11084@renji.com",[19],{"facility":20,"status":21,"city":22,"state":7,"zip":7,"country":23,"countryCode":24,"cosmosGeoPoint":25,"geoPoint":30,"contacts":31},"Department of Geriatrics, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.","RECRUITING","Shanghai","China","CN",{"type":26,"coordinates":27},"Point",[28,29],121.45806,31.22222,{"lat":29,"lon":28},[32],{"name":33,"role":15,"phone":16,"phoneExt":7,"email":17},"Rong Huang, Ph.D",{"type":35,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100608742","sarcopenia-metabolic-diseases-and-integrated-aging-longitudinal-evaluation-smile-100608742",false,"NCT07205510","Sarcopenia, Metabolic Diseases, and Integrated Aging Longitudinal Evaluation (SMILE)","Inclusion Criteria:\n\nAdults aged 18 and over\n\nExclusion Criteria:\n\n1. Does not cooperate in signing the informed consent form;\n2. Does not possess legal capacity;\n3. In a state of loss of consciousness;\n4. Suffering from severe mental illness, unable to communicate normally;\n5. The researcher believes that the subject has a disease that affects the assessment of results and is unsuitable for inclusion.",true,"ALL","18 Years",{"count":46,"type":47},10000,"ESTIMATED","OBSERVATIONAL","This study aims to establish an ambispective cohort platform centered on the pathological axis of \"sarcopenia-metabolic disorders-aging progression\", integrating multimodal data including demographic characteristics, lifestyle factors, clinical phenotypes, laboratory tests, medical imaging, and biospecimens. Namely 'Sarcopenia, Metabolic Diseases, and Integrated Aging Longitudinal Evaluation (SMILE)'.",[51,52,53,54,55],"Sarcopenia","Metabolic Diseases","All-cause Mortality","Aging","Cardiometabolic Diseases",[51,52,54,57,55],"All-cause mortality","2025-09-25",{"date":60,"type":61},"2025-10-03","ACTUAL",{"date":63,"type":61},"2020-12-01",{"date":65,"type":47},"2040-12-31",{"name":5,"class":6},1]