[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621301":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":25,"responsibleParty":39,"collaborators":10,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":10,"eligibilityCriteria":47,"healthyVolunteers":48,"sex":49,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":10,"studyType":55,"phases":10,"briefSummary":56,"conditions":57,"keywords":62,"overallStatus":27,"whyStopped":10,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":76},{"fullName":5,"class":6},"Singapore General Hospital","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Healthy controls",null,"Healthy controls with normal weight",{"label":13,"type":10,"description":14,"interventionNames":10},"Severe obestiy","Participants with Severe obesity",[16],{"name":17,"affiliation":5,"role":18},"Hong Chang Tan","PRINCIPAL_INVESTIGATOR",[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Hong Chang Tan, MD PhD","CONTACT","+65 63214658","tan.hong.chang@singhealth.com.sg",[26],{"facility":5,"status":27,"city":28,"state":10,"zip":10,"country":28,"countryCode":29,"cosmosGeoPoint":30,"geoPoint":35,"contacts":36},"RECRUITING","Singapore","SG",{"type":31,"coordinates":32},"Point",[33,34],103.85007,1.28967,{"lat":34,"lon":33},[37],{"name":21,"role":22,"phone":38,"phoneExt":10,"email":24},"‭6563214658‬",{"type":40,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100621301","scalp-hair-metabolomics-in-severe-obesity-100621301",false,"NCT07368842","Scalp Hair Metabolomics in Severe Obesity","Scalp Hair Metabolomics as a Novel Biomarker of Poor Metabolic Health in Individuals With Severe Obesity","Inclusion Criteria:\n\nAll subjects:\n\n1. Age 21-70 years\n2. Ability to provide informed consent\n\nHealthy weight controls:\n\n1. BMI of 18.5-24.9 kg\u002Fm2\n2. No chronic disease\n3. No long-term medications\n\nSevere obesity:\n\n1. BMI of \\> 32.5 kg\u002Fm2\n2. Scheduled to undergo bariatric surgery\n\nExclusion Criteria:\n\n1. Pregnancy\n2. Any factors likely to limit adherence to study protocol\n3. Any history of autoimmune or scarring alopecia (eg. alopecia areata, discoid lupus, lichen planopilaris)",true,"ALL","21 Years","70 Years",{"count":53,"type":54},60,"ESTIMATED","OBSERVATIONAL","The purpose of this research study is to investigate how body weight and weight-loss surgery affect the natural chemicals found in scalp hair over time. We will also find out how common and severe hair thinning\u002Fhair loss and muscle loss are in the first 6 months after bariatric surgery.",[58,59,60,61],"Obesity & Overweight","Hair Loss","Metabolomics","Bariatric Surgery",[63,64,65,66],"obesity","hair loss","metabolomics","bariatric surgery","2026-02-11",{"date":69,"type":70},"2026-02-13","ACTUAL",{"date":72,"type":70},"2026-02-07",{"date":74,"type":54},"2028-02",{"name":5,"class":6},1]