[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100589989":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":32,"centralContacts":33,"locations":43,"responsibleParty":260,"collaborators":262,"id":285,"slug":286,"hasResults":287,"nctId":288,"briefTitle":289,"officialTitle":290,"acronym":32,"eligibilityCriteria":291,"healthyVolunteers":287,"sex":292,"minAge":293,"maxAge":32,"enrollmentInfo":294,"targetDuration":32,"studyType":297,"phases":298,"briefSummary":300,"conditions":301,"keywords":304,"overallStatus":80,"whyStopped":32,"lastUpdateSubmitDate":311,"lastUpdatePostDateStruct":312,"startDateStruct":315,"completionDateStruct":317,"leadSponsor":319,"locationsCount":320},{"fullName":5,"class":6},"Technical University of Munich","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Conservative Group","EXPERIMENTAL","conservative group subjected to external collar bracing",[13],"Other: External immobilization with rigid cervical collar",{"label":15,"type":10,"description":16,"interventionNames":17},"Surgical Group","surgical group undergoing C1-2 instrumentation",[18],"Procedure: C1-2 instrumentation",[20,28],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","C1-2 instrumentation","Surgical fracture stabilization with a posterior screw-rod system from C1-2 from a posterior approach.\n\nThe routine surgery commonly lasts approximately 100 minutes and requires a hospital stay of about 6 days. An additional external bracing in the postoperative setting is not required.",[15],[26,27],"Spondylodesis","fusion",{"type":6,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"External immobilization with rigid cervical collar","External immobilization with a rigid cervical collar for 12 weeks. Compliance is monitored through patient diaries, recognizing the real-world challenges of consistent brace use. Lack of adherence is considered to reflect routine clinical practice. A typical drawback of the conservative intervention in daily practice is the absolute reliance on patient compliance to wear the collar continuously for at least 12 weeks, which poses a significant challenge to this treatment strategy.",[9],null,[34,39],{"name":35,"role":36,"phone":37,"phoneExt":32,"email":38},"Maria Wostrack, Prof. Dr.","CONTACT","+498941405386","Maria.wostrack@tum.de",{"name":40,"role":36,"phone":41,"phoneExt":32,"email":42},"Arthur Wagner, PD Dr.","+498941409619","arthur.wagner@tum.de",[44,63,78,94,107,117,130,143,156,169,182,195,208,221,234,247],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"LMU University Hospital","NOT_YET_RECRUITING","Munich","Bavaria","81377","Germany","DE",{"type":53,"coordinates":54},"Point",[55,56],11.57549,48.13743,{"lat":56,"lon":55},[59],{"name":60,"role":36,"phone":61,"phoneExt":32,"email":62},"Florian Ringel, Prof. Dr.","+49 89 4400-72591","florian.ringel@med.uni-muenchen.de",{"facility":64,"status":46,"city":65,"state":66,"zip":67,"country":50,"countryCode":51,"cosmosGeoPoint":68,"geoPoint":72,"contacts":73},"Center for Spinal Surgery and Neurotraumatology, Berufsgenossenschaftliche Unfallklinik","Frankfurt am Main","Hesse","60389",{"type":53,"coordinates":69},[70,71],8.68417,50.11552,{"lat":71,"lon":70},[74],{"name":75,"role":36,"phone":76,"phoneExt":32,"email":77},"Frank Kandziora, Prof. Dr.","+4969 475-2018","ws@bgu-frankfurt.de",{"facility":79,"status":80,"city":81,"state":82,"zip":83,"country":50,"countryCode":51,"cosmosGeoPoint":84,"geoPoint":88,"contacts":89},"Charité University Hospital Berlin","RECRUITING","Berlin","State of Berlin","10117",{"type":53,"coordinates":85},[86,87],13.41053,52.52437,{"lat":87,"lon":86},[90],{"name":91,"role":36,"phone":92,"phoneExt":32,"email":93},"Peter Vajkoczy, Prof. Dr.","+49 30 450 660 409","peter.vajkoczy@charite.de",{"facility":95,"status":46,"city":96,"state":32,"zip":32,"country":50,"countryCode":51,"cosmosGeoPoint":97,"geoPoint":101,"contacts":102},"Department of Neurosurgery, RWTH Aachen University","Aachen",{"type":53,"coordinates":98},[99,100],6.08342,50.77664,{"lat":100,"lon":99},[103],{"name":104,"role":36,"phone":105,"phoneExt":32,"email":106},"Christian Blume, Dr.","+49241 80-88476","cblume@ukaachen.de",{"facility":108,"status":46,"city":81,"state":32,"zip":32,"country":50,"countryCode":51,"cosmosGeoPoint":109,"geoPoint":111,"contacts":112},"Department of Neurosurgery and Spine Center, HELIOS Hospital Berlin Buch",{"type":53,"coordinates":110},[86,87],{"lat":87,"lon":86},[113],{"name":114,"role":36,"phone":115,"phoneExt":32,"email":116},"Yu-Mi Ryang, Prof. Dr.","+493094 01-54300","yumi.ryang@helios-gesundheit.de",{"facility":118,"status":46,"city":119,"state":32,"zip":32,"country":50,"countryCode":51,"cosmosGeoPoint":120,"geoPoint":124,"contacts":125},"Department of Orthopaedic and Traumatology, University of Cologne","Cologne",{"type":53,"coordinates":121},[122,123],6.95,50.93333,{"lat":123,"lon":122},[126],{"name":127,"role":36,"phone":128,"phoneExt":32,"email":129},"Peer Eysel, Prof. Dr.","+49 221 478-4601","peer.eysel@uk-koeln.de",{"facility":131,"status":46,"city":132,"state":32,"zip":32,"country":50,"countryCode":51,"cosmosGeoPoint":133,"geoPoint":137,"contacts":138},"Department of Orthopedics, Medical University at Dresden","Dresden",{"type":53,"coordinates":134},[135,136],13.73832,51.05089,{"lat":136,"lon":135},[139],{"name":140,"role":36,"phone":141,"phoneExt":32,"email":142},"Alexander Carl Disch, Prof. Dr.","+49351 458-3840","alexander.disch@uniklinikum-dresden.de",{"facility":144,"status":46,"city":145,"state":32,"zip":32,"country":50,"countryCode":51,"cosmosGeoPoint":146,"geoPoint":150,"contacts":151},"Department of Neurosurgery and Spine Surgery, University Hospital Essen","Essen",{"type":53,"coordinates":147},[148,149],7.01228,51.45657,{"lat":149,"lon":148},[152],{"name":153,"role":36,"phone":154,"phoneExt":32,"email":155},"Oliver Gembruch, Dr.","+49 (0)201 723 1210","neurosurgery@uk-essen.de",{"facility":157,"status":46,"city":158,"state":32,"zip":32,"country":50,"countryCode":51,"cosmosGeoPoint":159,"geoPoint":163,"contacts":164},"Department of Neurosurgery, University Medical Center Göttingen","Göttingen",{"type":53,"coordinates":160},[161,162],9.93228,51.53443,{"lat":162,"lon":161},[165],{"name":166,"role":36,"phone":167,"phoneExt":32,"email":168},"Veit Rohde, Prof. Dr.","+49551 39-61777","veit.rohde@med.uni-goettingen.de",{"facility":170,"status":46,"city":171,"state":32,"zip":32,"country":50,"countryCode":51,"cosmosGeoPoint":172,"geoPoint":176,"contacts":177},"Department of Trauma and Reconstructive Surgery, BG Klinikum Bergmannstrost Halle","Halle",{"type":53,"coordinates":173},[174,175],11.97947,51.48158,{"lat":175,"lon":174},[178],{"name":179,"role":36,"phone":180,"phoneExt":32,"email":181},"Bernhard Ulrich, Dr. med.","+49345 132 - 66 32","uc-leitendeaerzte@bergmannstrost.de",{"facility":183,"status":46,"city":184,"state":32,"zip":32,"country":50,"countryCode":51,"cosmosGeoPoint":185,"geoPoint":189,"contacts":190},"Department of Neurosurgery, University Hospital Heidelberg","Heidelberg",{"type":53,"coordinates":186},[187,188],8.69079,49.40768,{"lat":188,"lon":187},[191],{"name":192,"role":36,"phone":193,"phoneExt":32,"email":194},"Sandro Krieg, Prof. Dr.","+496221 56-6300","neurochirurgie@med.uni-heidelberg.de",{"facility":196,"status":80,"city":197,"state":32,"zip":32,"country":50,"countryCode":51,"cosmosGeoPoint":198,"geoPoint":202,"contacts":203},"Department of Neurosurgery, University Hospital of Lausitz","Lausitz",{"type":53,"coordinates":199},[200,201],13.34774,51.51313,{"lat":201,"lon":200},[204],{"name":205,"role":36,"phone":206,"phoneExt":32,"email":207},"Ehab Shiban, Prof. Dr.","+49 355 46 3111","neurochirurgie@mul-ct.de",{"facility":209,"status":46,"city":210,"state":32,"zip":32,"country":50,"countryCode":51,"cosmosGeoPoint":211,"geoPoint":215,"contacts":216},"Department of Orthopaedics, Trauma Surgery and Plastic Surgery, University of Leipzig","Leipzig",{"type":53,"coordinates":212},[213,214],12.37129,51.33962,{"lat":214,"lon":213},[217],{"name":218,"role":36,"phone":219,"phoneExt":32,"email":220},"Nicolas von der Höh, Dr.","+49341 - 97 23103","nicolas.vonderhoeh@medizin.uni-leipzig.de",{"facility":222,"status":46,"city":223,"state":32,"zip":32,"country":50,"countryCode":51,"cosmosGeoPoint":224,"geoPoint":228,"contacts":229},"Spine Surgery, Orthopedic Hospital Markgröningen GmbH","Markgröningen",{"type":53,"coordinates":225},[226,227],9.08059,48.90493,{"lat":227,"lon":226},[230],{"name":231,"role":36,"phone":232,"phoneExt":32,"email":233},"Marc Dreimann, Dr.","+497145-91-53241","gabriela.schroeder@rkh-gesundheit.de",{"facility":235,"status":46,"city":236,"state":32,"zip":32,"country":50,"countryCode":51,"cosmosGeoPoint":237,"geoPoint":241,"contacts":242},"BG Trauma Centre, Eberhard Karls University of Tuebingen","Tübingen",{"type":53,"coordinates":238},[239,240],9.05222,48.52266,{"lat":240,"lon":239},[243],{"name":244,"role":36,"phone":245,"phoneExt":32,"email":246},"Andreas Badke, Dr.","+497071 606-1046","ABadke@bgu-tuebingen.de",{"facility":248,"status":46,"city":249,"state":32,"zip":32,"country":50,"countryCode":51,"cosmosGeoPoint":250,"geoPoint":254,"contacts":255},"Spine Center, St. Josefs-Hospital Wiesbaden","Wiesbaden",{"type":53,"coordinates":251},[252,253],8.24435,50.08601,{"lat":253,"lon":252},[256],{"name":257,"role":36,"phone":258,"phoneExt":32,"email":259},"Philipp Hartung, Dr.","+49611 177 3701","phartung@joho.de",{"type":261,"investigatorFullName":32,"investigatorTitle":32,"investigatorAffiliation":32,"oldNameTitle":32,"oldOrganization":32},"SPONSOR",[263,265,267,269,271,273,275,278,280,283],{"name":264,"class":6},"St. Josefs-Hospital Wiesbaden GmbH",{"name":266,"class":6},"Medical University of Cologne",{"name":268,"class":6},"BG Trauma Center Tuebingen",{"name":270,"class":6},"RWTH Aachen University",{"name":272,"class":6},"University Hospital Heidelberg",{"name":274,"class":6},"University Hospital, Essen",{"name":276,"class":277},"BG Klinikum Bergmannstrost, Halle, Germany","UNKNOWN",{"name":279,"class":6},"Helios Klinikum Berlin-Buch",{"name":281,"class":282},"German Federal Ministry of Education and Research","OTHER_GOV",{"name":284,"class":6},"Charite University, Berlin, Germany","100589989","score-study-comparing-surgery-and-rigid-collar-treatment-for-odontoid-fractures-in-adults-over-70-100589989",false,"NCT06961578","SCORE Study: Comparing Surgery and Rigid Collar Treatment for Odontoid Fractures in Adults Over 70","Surgical Versus Conservative Treatment of Odontoid Fractures in the Elderly: A Randomised Controlled Clinical Study (SCORE)","Inclusion Criteria:\n\n* At least 70 years old\n* Acute unstable OFs (types II, III as classified by Anderson and d'Alonzo, and atypical)\n* Less than two weeks post injury\n* Written informed consent\n\nExclusion Criteria:\n\n* Previous treatment for odontoid fracture\n* Concomitant fractures of the subaxial cervical spine necessitating surgery\n* Significant comorbidity resulting in inoperability of the patient: i.e. ASA score \\> 4\n* Neurological compromise due to displaced fracture","ALL","70 Years",{"count":295,"type":296},322,"ESTIMATED","INTERVENTIONAL",[299],"NA","The goal of this clinical trial is to compare two treatment options-surgery or rigid collar bracing-for unstable neck fractures (odontoid fractures) in adults aged 70 years and older. These fractures are common in older adults and can significantly impact mobility, independence, and quality of life. There is currently no clear evidence to determine which treatment is better for this population. The main questions it aims to answer are:\n\n* Does surgery or conservative collar treatment lead to better improvement in daily living, measured by the Barthel Index, after 12 weeks?\n* What are the differences in pain, disability, and quality of life between the two treatments?\n\nThe study team will compare patients who receive surgical stabilization with those who are treated with a rigid cervical collar to see which approach supports better functional outcomes and healing.\n\nParticipants will:\n\n* be randomly assigned to either surgery (posterior C1-C2 screw-rod fixation) or conservative collar treatment\n* attend study visits at 12 weeks and 6 months\n* complete questionnaires on daily functioning, pain, and quality of life\n* undergo CT scans and other medical assessments\n* record collar use (for conservative group) in a diary\n* be monitored for any complications or changes in treatment (including crossover to surgery if needed)\n\nThe study aims to include 322 participants to provide evidence on which treatment helps older adults recover better from odontoid fractures with fewer complications and improved quality of life.",[302,303],"Odontoid Fracture","Elderly",[305,306,307,308,309,310],"Odontoid fracture","C2 fracture","atlantoaxial instability","atlantoaxial fusion","Barthel Index","functional outcome","2026-05-05",{"date":313,"type":314},"2026-05-06","ACTUAL",{"date":316,"type":314},"2025-08-13",{"date":318,"type":296},"2028-06-01",{"name":5,"class":6},16]