[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100492000":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":22,"centralContacts":26,"locations":36,"responsibleParty":53,"collaborators":57,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":65,"acronym":10,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":10,"maxAge":10,"enrollmentInfo":69,"targetDuration":72,"studyType":73,"phases":10,"briefSummary":74,"conditions":75,"keywords":79,"overallStatus":39,"whyStopped":10,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Zhujiang Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Multiple myeloma",null,"Multiple myeloma (MM) is a hematologic malignant tumor characterized by abnormally cloned plasma cells in bone marrow, whose growth can lead to destructive bone injury, acute kidney injury, anemia, and hypercalcemia.",[13],"Other: Observational studies, no intervention",{"label":15,"type":10,"description":16,"interventionNames":17},"Healthy control","Individuals in good health without obvious disease and with normal physical examination report; Avoid people who have not suffered from major chronic diseases in recent years, such as hypertension, diabetes, chronic kidney disease, etc; controls were appropriately selected that matched cases for age and sex.",[13],[19],{"type":6,"name":20,"description":20,"armGroupLabels":21,"otherNames":10},"Observational studies, no intervention",[15,9],[23],{"name":24,"affiliation":5,"role":25},"Hongwei Zhou, Professor","STUDY_CHAIR",[27,33],{"name":28,"role":29,"phone":30,"phoneExt":31,"email":32},"Nianyi Zeng","CONTACT","13928801657","+86","zengny1@i.smu.edu.cn",{"name":24,"role":29,"phone":34,"phoneExt":31,"email":35},"18688489622","hzhou@smu.edu.cn",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Zhujiang Hospital of Southern Medical University","RECRUITING","Guangzhou","Guangdong","510000","China","CN",{"type":46,"coordinates":47},"Point",[48,49],113.25,23.11667,{"lat":49,"lon":48},[52],{"name":24,"role":29,"phone":34,"phoneExt":10,"email":35},{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Hongwei Zhou","Professor",[58],{"name":59,"class":60},"National Natural Science Foundation of China","OTHER_GOV","100492000","screening-and-therapeutic-monitoring-of-multiple-myeloma-by-maldi-tof-ms-analysis-100492000",false,"NCT05686447","Screening and Therapeutic Monitoring of Multiple Myeloma by MALDI-TOF MS Analysis","Inclusion Criteria:(1) Inclusion criteria for cases: Serum samples from related people diagnosed with multiple myeloma were included in MALDI-TOF-MS analysis by serum protein electrophoresis (SPEP), serum immunofixation electrophoresis (IFE), Ig isotype detection and other methods. (2) Inclusion criteria of the controls were as follows: individuals in good health without obvious disease and with normal physical examination report; Avoid people who have not suffered from major chronic diseases in recent years, such as hypertension, diabetes, chronic kidney disease, etc; controls were appropriately selected that matched cases for age and sex.\n\n\\-\n\nExclusion Criteria: samples with incomplete sample information and untraceable source; Samples whose sample volume is insufficient for testing; Samples that do not meet the requirements for sample collection and storage\n\n\\-",true,"ALL",{"count":70,"type":71},200,"ESTIMATED","2 Years","OBSERVATIONAL","To provide a comprehensive MALDI-TOF mass spectrometry method for detecting, characterizing, and quantifying M-protein, and to track M-protein in a very sensitive and specific manner during patient treatment, providing a more precise test for diagnosing disease and monitoring patient response to treatment.",[76,77,78],"Monoclonal Gammopathies","Multiple Myeloma","M-protein",[78],"2025-04-02",{"date":82,"type":83},"2025-04-06","ACTUAL",{"date":85,"type":83},"2023-01-01",{"date":87,"type":71},"2026-07-31",{"name":5,"class":6},1]