[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100549772":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":10,"locations":22,"responsibleParty":34,"collaborators":36,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":48,"sex":49,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":10,"studyType":55,"phases":10,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":65,"whyStopped":10,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"Universidade do Porto","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Stable chest pain and unknown CAD who underwent CTCA and CCS in the same scanning session",null,"CAD: Presence of minimal coronary artery disease (i.e., coronary stenosis 0-25%) Normal coronary arteries: No visible coronary atherosclerosis",[13],"Diagnostic Test: CT coronary angiography and non-contrast CT",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DIAGNOSTIC_TEST","CT coronary angiography and non-contrast CT","A CTCA is an X-ray computed tomography of the coronary arteries that allows visualization of coronary plaques with high temporal and spatial resolution, however, it implies the use of iodine contrast and exposition to clinically significant ionizing radiation.\n\nNon-contrast ECG-gated CT (\"calcium score\" - CCS image). A non-contrast cardiac CT for CCS can be performed very quickly with significantly lower radiation (\\~6 times lower) than CTCA and without the need for contrast.",[9],[21],"Non-contrast computed tomography",[23],{"facility":24,"status":10,"city":25,"state":10,"zip":10,"country":26,"countryCode":27,"cosmosGeoPoint":28,"geoPoint":33,"contacts":10},"Faculty of Medicine of Porto","Porto","Portugal","PT",{"type":29,"coordinates":30},"Point",[31,32],-8.61097,41.1485,{"lat":32,"lon":31},{"type":35,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[37,39],{"name":38,"class":6},"University of Oxford",{"name":40,"class":6},"University of Edinburgh","100549772","screening-coronary-artery-disease-using-artificial-intelligence-in-non-contrast-computed-tomography-100549772",false,"NCT06438393","Screening Coronary Artery Disease Using artiFicial intelligencE in Non-contrast Computed Tomography","SAFE-CT","Inclusion Criteria:\n\n\\- Patient with stable chest pain who underwent a CTCA\n\nExclusion Criteria:\n\n* Missing non-contrast CT image (coronary calcium score image)\n* Known coronary artery disease\n* Prior myocardial infarction\n* Prior PCI or CABG",true,"ALL","18 Years","100 Years",{"count":53,"type":54},1000,"ESTIMATED","OBSERVATIONAL","This project aims to improve direct patient care by reducing the risks of futile exposure to ionizing radiation and iodinated contrast in patients referred for coronary computed tomography angiography",[58,59],"Coronary Artery Disease","Coronary Atheroscleroses",[61,62,63,64,21],"Artificial intelligence","Radiomics","Deep learning","Coronary artery disease","NOT_YET_RECRUITING","2024-05-27",{"date":68,"type":69},"2024-05-31","ACTUAL",{"date":71,"type":54},"2024-06",{"date":73,"type":54},"2027-12",{"name":5,"class":6},1]