[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100497860":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":10,"locations":27,"responsibleParty":46,"collaborators":48,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":60,"acronym":10,"eligibilityCriteria":61,"healthyVolunteers":58,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":68,"studyType":69,"phases":10,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":30,"whyStopped":10,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"The University of Hong Kong","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"First degree relatives of lung cancer patients",null,"Age 50-75, men or women, smokers or non-smokers. Being first degree relatives (siblings, children and parents) of lung cancer subjects. Having no known lung cancer before.",[13],"Diagnostic Test: Low dose CT thorax",{"label":15,"type":10,"description":16,"interventionNames":17},"Control group","Non-lung cancer subjects who are not related any lung cancer patients",[13],[19,24],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"DIAGNOSTIC_TEST","Low dose CT thorax","A multi-detector row CT scanner with minimum section collimation of ≤1 mm and minimum number of data acquisition channels ≥ 16will be employed.",[9],{"type":20,"name":21,"description":25,"armGroupLabels":26,"otherNames":10},"Control subjects will also proceed to CT thorax, and outcome measures be compared to subjects",[15],[28],{"facility":29,"status":30,"city":31,"state":31,"zip":32,"country":31,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"University of Hong Kong","RECRUITING","Hong Kong","0","HK",{"type":35,"coordinates":36},"Point",[37,38],114.17469,22.27832,{"lat":38,"lon":37},[41],{"name":42,"role":43,"phone":44,"phoneExt":10,"email":45},"David CL Lam, MBBS, FRCP(Edin), FCCP, FACP","CONTACT","+852 2255 5814","dcllam@hku.hk",{"type":47,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[49,51,53],{"name":50,"class":6},"The Queen Elizabeth Hospital",{"name":52,"class":6},"Kwong Wah Hospital",{"name":54,"class":55},"Hong Kong Sanatorium & Hospital","INDUSTRY","100497860","screening-for-lung-cancer-in-subjects-with-family-history-of-lung-cancer-100497860",false,"NCT05762731","Screening for Lung Cancer in Subjects With Family History of Lung Cancer","Inclusion Criteria:\n\n* Age 50-75, men or women, smokers or non-smokers\n* Being first degree relatives (Siblings, children, and parents) of lung cancer subjects\n* Having no known lung cancer before\n\nExclusion Criteria:\n\n* Non-Chinese\n* Mentally incompetent to give informed consent","ALL","50 Years","75 Years",{"count":66,"type":67},1520,"ESTIMATED","3 Years","OBSERVATIONAL","Lung cancer can be detected via screening of high-risk individuals, i.e current or ex-heavy smokers, with low-dose computer tomography (LDCT) of thorax. The National Lung Screening Trial in US and the NELSON trial in Europe demonstrated reduction in lung cancer mortality with LDCT screening for lung cancer. In Hong Kong, however, there is a prominence of female never-smokers with lung cancer. There is no identifiable risk factors for non-smokers with lung cancer except family history of lung cancer. The hypothesis is that lung cancer screening for subjects with family history of lung cancer, can detect early lung cancer.",[72],"Lung Cancer",[74,75,76],"Lung cancer","Screening","Family history","2026-06-07",{"date":79,"type":80},"2026-06-09","ACTUAL",{"date":82,"type":80},"2023-02-01",{"date":84,"type":67},"2028-05",{"name":5,"class":6},1]