[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100467665":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":23,"centralContacts":28,"locations":22,"responsibleParty":38,"collaborators":22,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":42,"sex":48,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":22,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":65,"whyStopped":22,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":22},{"fullName":5,"class":6},"University Hospital, Grenoble","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"First line coronary scanner group","The patient will benefit from a coronary CT scan in 1st line (evaluation of the coronary anatomy), then according to the result it will be managed according to the CAD-RADS decision algorithm.",[12],"Other: Coronary CT in 1st line compared to the strategy with functional test in 1st line in patient at Intermediate Risk of Developing Stable Coronary Disease:",{"label":14,"type":6,"description":15,"interventionNames":16},"First line functional test strategy group","The patient benefits from a functional test in 1st line (search for myocardial ischemia by myocardial scintigraphy: SPECT, stress echography, or MRI), then according to the result he will be managed in accordance with the European recommendations.",[12],[18],{"type":6,"name":19,"description":20,"armGroupLabels":21,"otherNames":22},"Coronary CT in 1st line compared to the strategy with functional test in 1st line in patient at Intermediate Risk of Developing Stable Coronary Disease:","Coronary CT in 1st line compared to the strategy with functional test in 1st line in Patients at Intermediate Risk of Developing Stable Coronary Disease:",[9,14],null,[24],{"name":25,"affiliation":26,"role":27},"Gilles Barone-Rochette, Pr","CHU Grenoble Alpes","PRINCIPAL_INVESTIGATOR",[29,34],{"name":30,"role":31,"phone":32,"phoneExt":22,"email":33},"Laura Chambon","CONTACT","04 76 76 89 35","lchambon@chu-grenoble.fr",{"name":35,"role":31,"phone":36,"phoneExt":22,"email":37},"Clémence Charlon","04 76 76 66 52","ccharlon@chu-grenoble.fr",{"type":39,"investigatorFullName":22,"investigatorTitle":22,"investigatorAffiliation":22,"oldNameTitle":22,"oldOrganization":22},"SPONSOR","100467665","screening-of-coronary-artery-disease-100467665",false,"NCT05369728","Screening Of CoRonary ArTEry diSease","Medico-economic Evaluation of a Strategy With Coronary CT as First Line (CCTA) Compared With the Strategy With Functional Test as First Line, in Patients at Intermediate Risk of Developing Stable Coronary Disease.","SOCRATES","Inclusion Criteria:\n\n* Patients aged 18 to 75 years\n* Symptomatic patient in whom CAD cannot be excluded by clinical evaluation alone : patient with a pre-test or \"intermediate\" clinical probability indicating imaging test according to European recommendations\n* Patient affiliated to the social security system or beneficiary of such a system\n* Written informed consent\n\nExclusion Criteria:\n\n* Pre-test probability \"low\" \\\u003C 5% or 5-15% without additive pejorative factors\n* Clinical probability of \"high\" CAD, defined by symptoms typical of low exercise levels not responding to medical therapies\n* Known history of CAD\n* Severe impairment of left ventricular ejection fraction \\\u003C 40%.\n* Known chronic renal failure not on dialysis (GFR \\\u003C30 ml \u002F min \u002F1.73 m²)\n* Patient considered unfit for the study according to the investigator's judgement and in particular the impossibility of performing an anatomical and\u002For functional test of ischemia of the coronary disease\n* Patient in a period of exclusion for another study\n* Persons referred to in articles L1121-5 to L1121-8 of the public health code\n* Patient participating in another interventional research","ALL","18 Years","75 Years",{"count":52,"type":53},800,"ESTIMATED","INTERVENTIONAL",[56],"NA","This study is a randomized trial with the objective of comparing the cost-effectiveness of the 2 recommended strategies: CCTA vs functional tests, allowing the evaluation of the quality of life of these patients in relation to the health resources used.\n\nIn symptomatic patients with an intermediate probability of having stable CAD, i.e., whose pretest or clinical probability does not allow the elimination of the disease, and in patients without anginal symptoms for low levels of exercise who do not respond to medical therapy, in France, the diagnostic care pathways have become mature enough to set up a pragmatic prospective randomized trial with the objective of comparing the cost-effectiveness of the 2 recommended strategies: CCTA vs.\n\nProbabilistic medico-economic reasoning makes it possible to establish this two-way hypothesis more easily than in clinical research without the need to impose the superiority of one of the strategies.",[59,60],"Cardiology","Coronary Artery Disease",[62,63,64],"Medico-economic study","Coronary CT scanner","Cardiac functionel test","NOT_YET_RECRUITING","2022-05-05",{"date":68,"type":69},"2022-05-11","ACTUAL",{"date":71,"type":53},"2022-05",{"date":73,"type":53},"2026-10",{"name":5,"class":6}]