[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100399169":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":19,"locations":28,"responsibleParty":406,"collaborators":10,"id":408,"slug":409,"hasResults":410,"nctId":411,"briefTitle":412,"officialTitle":413,"acronym":414,"eligibilityCriteria":415,"healthyVolunteers":410,"sex":416,"minAge":10,"maxAge":417,"enrollmentInfo":418,"targetDuration":10,"studyType":421,"phases":10,"briefSummary":422,"conditions":423,"keywords":10,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":425,"lastUpdatePostDateStruct":426,"startDateStruct":429,"completionDateStruct":431,"leadSponsor":433,"locationsCount":434},{"fullName":5,"class":6},"Gustave Roussy, Cancer Campus, Grand Paris","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients in therapeutic failure or relapse",null,"Any child, adolescent or young adult, treated for a pediatric tumor or leukemia, in therapeutic failure or relapse without standard treatment option, not eligible \u002F refusal of inclusion in a clinical study open on the territory and treated with an innovative drug within the framework of a compassionate use or outside marketing authorization, in one of the centers of the SFCE (Société Française des Cancers de l' Enfant)",[13],"Other: Data collection",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Data collection","In particular, the patient's demographic data, medical history, previous and concomitant treatments, data on the treatment of interest (legal framework, compassionate use\u002F off-label), dosage, start date, etc.), clinical data will be collected. biological (including molecular profiling of the tumor if available) and radiological follow-up, information on adverse effects. The data to be filled in is that of the CERFA pharmacovigilance form of the ANSM, but additional fields can be created if necessary.",[9],[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Pablo BERLANGA, MD","CONTACT","+33 (0)1 42 11 42 11","pablo.berlanga@gustaveroussy.fr",{"name":26,"role":22,"phone":23,"phoneExt":10,"email":27},"Lee Aymar NDOUNGA DIAKOU, PhD","Leeaymar.NDOUNGA-DIAKOU@gustaveroussy.fr",[29,45,57,69,81,93,106,118,130,142,154,166,175,187,199,208,220,232,244,256,268,280,289,298,310,322,334,346,358,370,382,394],{"facility":30,"status":31,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Gustave Roussy","RECRUITING","Villejuif","Val de Marne","94805","France","FR",{"type":38,"coordinates":39},"Point",[40,41],2.35992,48.7939,{"lat":41,"lon":40},[44],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},{"facility":46,"status":31,"city":47,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":48,"geoPoint":52,"contacts":53},"CHU Amiens","Amiens",{"type":38,"coordinates":49},[50,51],2.3,49.9,{"lat":51,"lon":50},[54],{"name":55,"role":22,"phone":10,"phoneExt":10,"email":56},"Leslie ANDRY, MD","Andry.Leslie@chu-amiens.fr",{"facility":58,"status":31,"city":59,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":60,"geoPoint":64,"contacts":65},"CHU Angers","Angers",{"type":38,"coordinates":61},[62,63],-0.55202,47.47156,{"lat":63,"lon":62},[66],{"name":67,"role":22,"phone":10,"phoneExt":10,"email":68},"Emilie DE CARLI, MD","EmDeCarli@chu-angers.fr",{"facility":70,"status":31,"city":71,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":72,"geoPoint":76,"contacts":77},"CHU Besançon","Besançon",{"type":38,"coordinates":73},[74,75],6.01815,47.24878,{"lat":75,"lon":74},[78],{"name":79,"role":22,"phone":10,"phoneExt":10,"email":80},"Sébastien KLEIN, MD","s1klein@chu-besancon.fr",{"facility":82,"status":31,"city":83,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":84,"geoPoint":88,"contacts":89},"CHU Bordeaux","Bordeaux",{"type":38,"coordinates":85},[86,87],-0.58046,44.84124,{"lat":87,"lon":86},[90],{"name":91,"role":22,"phone":10,"phoneExt":10,"email":92},"Stéphane DUCASSOU, MD","stephane.ducassou@chu-bordeaux.fr",{"facility":94,"status":31,"city":95,"state":10,"zip":96,"country":35,"countryCode":36,"cosmosGeoPoint":97,"geoPoint":101,"contacts":102},"CHU Morvan","Brest","29200",{"type":38,"coordinates":98},[99,100],-4.48628,48.39029,{"lat":100,"lon":99},[103],{"name":104,"role":22,"phone":10,"phoneExt":10,"email":105},"Liana Carausu","liana.carausu@chu-brest.fr",{"facility":107,"status":31,"city":108,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":109,"geoPoint":113,"contacts":114},"CHU CAEN","Caen",{"type":38,"coordinates":110},[111,112],-0.35912,49.18585,{"lat":112,"lon":111},[115],{"name":116,"role":22,"phone":10,"phoneExt":10,"email":117},"Damien BODET, MD","bodet-d@chu-caen.fr",{"facility":119,"status":31,"city":120,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":121,"geoPoint":125,"contacts":126},"CHU Clermont-Ferrand","Clermont-Ferrand",{"type":38,"coordinates":122},[123,124],3.08682,45.77969,{"lat":124,"lon":123},[127],{"name":128,"role":22,"phone":10,"phoneExt":10,"email":129},"Justyna KANOLD","jkanold@chu-clermontferrand.fr",{"facility":131,"status":31,"city":132,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":133,"geoPoint":137,"contacts":138},"CHU Dijon","Dijon",{"type":38,"coordinates":134},[135,136],5.01391,47.31344,{"lat":136,"lon":135},[139],{"name":140,"role":22,"phone":10,"phoneExt":10,"email":141},"Claire BRIANDET, MD","claire.briandet@chu-dijon.fr",{"facility":143,"status":31,"city":144,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":145,"geoPoint":149,"contacts":150},"CHU Grenoble","Grenoble",{"type":38,"coordinates":146},[147,148],5.71479,45.17869,{"lat":148,"lon":147},[151],{"name":152,"role":22,"phone":10,"phoneExt":10,"email":153},"Dominique PLANTAZ, MD","Dplantaz@chu-grenoble.fr",{"facility":155,"status":31,"city":156,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":157,"geoPoint":161,"contacts":162},"Centre Oscar Lambret","Lille",{"type":38,"coordinates":158},[159,160],3.05512,50.63391,{"lat":160,"lon":159},[163],{"name":164,"role":22,"phone":10,"phoneExt":10,"email":165},"Sandra RAIMBAULT, MD","s-raimbault@o-lambret.fr",{"facility":167,"status":31,"city":156,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":168,"geoPoint":170,"contacts":171},"CHU Lille",{"type":38,"coordinates":169},[159,160],{"lat":160,"lon":159},[172],{"name":173,"role":22,"phone":10,"phoneExt":10,"email":174},"Brigitte NELKEN, MD","brigitte.nelken@chru-lille.fr",{"facility":176,"status":31,"city":177,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":178,"geoPoint":182,"contacts":183},"CHU Limoges","Limoges",{"type":38,"coordinates":179},[180,181],1.24759,45.83362,{"lat":181,"lon":180},[184],{"name":185,"role":22,"phone":10,"phoneExt":10,"email":186},"Christophe PIGUET, MD","Christophe.Piguet@chu-limoges.fr",{"facility":188,"status":31,"city":189,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":190,"geoPoint":194,"contacts":195},"Centre Léon Bérard","Lyon",{"type":38,"coordinates":191},[192,193],4.84789,45.74906,{"lat":193,"lon":192},[196],{"name":197,"role":22,"phone":10,"phoneExt":10,"email":198},"Nadège CORRADINI, MD","Nadege.CORRADINI@ihope.fr",{"facility":200,"status":31,"city":189,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":201,"geoPoint":203,"contacts":204},"CHU Lyon",{"type":38,"coordinates":202},[192,193],{"lat":193,"lon":192},[205],{"name":206,"role":22,"phone":10,"phoneExt":10,"email":207},"Carine HALFON-DOMENECH, MD","carine.halfondomenech@ihope.fr",{"facility":209,"status":31,"city":210,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":211,"geoPoint":215,"contacts":216},"Hôpital de La Timone","Marseille",{"type":38,"coordinates":212},[213,214],5.38107,43.29695,{"lat":214,"lon":213},[217],{"name":218,"role":22,"phone":10,"phoneExt":10,"email":219},"Nicolas ANDRE, MD","Nicolas.ANDRE@ap-hm.fr",{"facility":221,"status":31,"city":222,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":223,"geoPoint":227,"contacts":228},"CHU Montpellier","Montpellier",{"type":38,"coordinates":224},[225,226],3.87635,43.61093,{"lat":226,"lon":225},[229],{"name":230,"role":22,"phone":10,"phoneExt":10,"email":231},"Laure SAUMET, MD","l-saumet@chu-montpellier.fr",{"facility":233,"status":31,"city":234,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":235,"geoPoint":239,"contacts":240},"CHU Nancy","Nancy",{"type":38,"coordinates":236},[237,238],6.18496,48.68439,{"lat":238,"lon":237},[241],{"name":242,"role":22,"phone":10,"phoneExt":10,"email":243},"Pascal CHASTAGNER, MD","p.chastagner@chru-nancy.fr",{"facility":245,"status":31,"city":246,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":247,"geoPoint":251,"contacts":252},"CHU Nantes","Nantes",{"type":38,"coordinates":248},[249,250],-1.55336,47.21725,{"lat":250,"lon":249},[253],{"name":254,"role":22,"phone":10,"phoneExt":10,"email":255},"Morgane CLEIREC, MD","morgane.cleirec@chu-nantes.fr",{"facility":257,"status":31,"city":258,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":259,"geoPoint":263,"contacts":264},"CHU Nice","Nice",{"type":38,"coordinates":260},[261,262],7.26608,43.70313,{"lat":262,"lon":261},[265],{"name":266,"role":22,"phone":10,"phoneExt":10,"email":267},"Joy BENADIBA, MD","benadiba.j@chu-nice.fr",{"facility":269,"status":31,"city":270,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":271,"geoPoint":275,"contacts":276},"Hôpital Armand Trousseau","Paris",{"type":38,"coordinates":272},[273,274],2.3488,48.85341,{"lat":274,"lon":273},[277],{"name":278,"role":22,"phone":10,"phoneExt":10,"email":279},"Arnaud PETIT, MD","arnaud.petit@aphp.fr",{"facility":281,"status":31,"city":270,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":282,"geoPoint":284,"contacts":285},"Hôpital Robert-Debré",{"type":38,"coordinates":283},[273,274],{"lat":274,"lon":273},[286],{"name":287,"role":22,"phone":10,"phoneExt":10,"email":288},"Marion STRULLU, MD","marion.strullu@aphp.fr",{"facility":290,"status":31,"city":270,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":291,"geoPoint":293,"contacts":294},"Institut Curie",{"type":38,"coordinates":292},[273,274],{"lat":274,"lon":273},[295],{"name":296,"role":22,"phone":10,"phoneExt":10,"email":297},"Isabelle AERTS, MD","isabelle.aerts@curie.fr",{"facility":299,"status":31,"city":300,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":301,"geoPoint":305,"contacts":306},"CHU Poitiers","Poitiers",{"type":38,"coordinates":302},[303,304],0.34348,46.58261,{"lat":304,"lon":303},[307],{"name":308,"role":22,"phone":10,"phoneExt":10,"email":309},"Frederic MILLOT, MD","f.millot@chu-poitiers.fr",{"facility":311,"status":31,"city":312,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":313,"geoPoint":317,"contacts":318},"CHU Reims","Reims",{"type":38,"coordinates":314},[315,316],4.02853,49.26526,{"lat":316,"lon":315},[319],{"name":320,"role":22,"phone":10,"phoneExt":10,"email":321},"Claire PUCHART, MD","cpluchart@chu-reims.fr",{"facility":323,"status":31,"city":324,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":325,"geoPoint":329,"contacts":330},"CHU Rennes","Rennes",{"type":38,"coordinates":326},[327,328],-1.67431,48.11109,{"lat":328,"lon":327},[331],{"name":332,"role":22,"phone":10,"phoneExt":10,"email":333},"Chloé PUISIEUX, MD","Chloe.PUISEUX@chu-rennes.fr",{"facility":335,"status":31,"city":336,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":337,"geoPoint":341,"contacts":342},"CHU Rouen","Rouen",{"type":38,"coordinates":338},[339,340],1.09932,49.44313,{"lat":340,"lon":339},[343],{"name":344,"role":22,"phone":10,"phoneExt":10,"email":345},"Pascal SCHNEIDER","Pascale.Schneider@chu-rouen.fr",{"facility":347,"status":31,"city":348,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":349,"geoPoint":353,"contacts":354},"CHU La Réunion","Saint-Denis",{"type":38,"coordinates":350},[351,352],2.35387,48.93564,{"lat":352,"lon":351},[355],{"name":356,"role":22,"phone":10,"phoneExt":10,"email":357},"Yves REGUERRE, MD","yves.reguerre@chu-reunion.fr",{"facility":359,"status":31,"city":360,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":361,"geoPoint":365,"contacts":366},"CHU Saint-Etienne","Saint-Etienne",{"type":38,"coordinates":362},[363,364],4.39,45.43389,{"lat":364,"lon":363},[367],{"name":368,"role":22,"phone":10,"phoneExt":10,"email":369},"Sandrine THOUVENIN, MD","sandrine.thouvenin@chu-st-etienne.fr",{"facility":371,"status":31,"city":372,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":373,"geoPoint":377,"contacts":378},"CHU Strasbourg","Strasbourg",{"type":38,"coordinates":374},[375,376],7.74553,48.58392,{"lat":376,"lon":375},[379],{"name":380,"role":22,"phone":10,"phoneExt":10,"email":381},"Natacha ENTZ-WERLE","Natacha.Entz-Werle@chru-strasbourg.fr",{"facility":383,"status":31,"city":384,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":385,"geoPoint":389,"contacts":390},"CHU Toulouse","Toulouse",{"type":38,"coordinates":386},[387,388],1.44367,43.60426,{"lat":388,"lon":387},[391],{"name":392,"role":22,"phone":10,"phoneExt":10,"email":393},"Marion Gambart, MD","gambart.m@chu-toulouse.fr",{"facility":395,"status":31,"city":396,"state":10,"zip":10,"country":35,"countryCode":36,"cosmosGeoPoint":397,"geoPoint":401,"contacts":402},"CHU Tours","Tours",{"type":38,"coordinates":398},[399,400],0.70398,47.39484,{"lat":400,"lon":399},[403],{"name":404,"role":22,"phone":10,"phoneExt":10,"email":405},"Jill SERRE, MD","J.SERRE@chu-tours.fr",{"type":407,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100399169","securing-access-to-innovative-molecules-in-oncology-and-hematology-for-children-adolescents-and-young-adults-100399169",false,"NCT04477681","Securing Access to Innovative Molecules in Oncology and Hematology for Children, Adolescents and Young Adults","Securing Access to Innovative Molecules in Oncology and Hematology for Children, Adolescents and Young Adults in Therapeutic Failure or Relapse and Not Eligible for a Clinical Trial: a Project of the SFCE","SACHA","Inclusion Criteria:\n\n* Age ≤ 25 years old at the time of inclusion in the study\n* Patient with a pediatric tumor or leukemia in therapeutic failure or relapse without standard therapeutic options. Exceptionally, patients on the first line of treatment without standard therapeutic options may also be included (eg g: inoperable plexiform neurofibroma and MEK inhibitors, childhood fibrosarcoma and NTRK inhibitors).\n* Patient not eligible for an early phase clinical trial open to inclusion on French territory or refusal of inclusion\n* Patient treated with a new drug discussed at a RCPPI as part of a compassionate use issued by the ANSM or an off-label prescription of a drug of interest already authorized in adults.\n* Patients treated in one of the SFCE centers authorized to prescribe chemotherapy\n* Patient who did not object to participate after being informed of the study. The patient must be able and willing to cooperate in the study.\n\nExclusion Criteria:\n\n* Patient included in an early phase clinical trial open to inclusions on French territory.\n* Oral refusal to participate by the patient or their legal representatives, in reading the information note specific to the study\n* Patient under guardianship or curatorship, deprived of liberty or in the impossibility of expressing opposition to participating in the study","ALL","25 Years",{"count":419,"type":420},1150,"ESTIMATED","OBSERVATIONAL","It involves collecting safety and efficacy data, under the actual conditions of use of medicines in children and adolescents, using a validated tool (Ennov EDC) and relying on the network of Interregional pediatric oncology appeal organizations (RIOs) identified by INCa since 2010 and responsible for the organization of Pluridisciplinary Pediatric Interregional (RCPPI) and National Consultative Meetings which discuss each case of relapse in order to define the best therapeutic options.",[424],"Pediatric Cancer","2026-03-27",{"date":427,"type":428},"2026-03-31","ACTUAL",{"date":430,"type":428},"2020-04-09",{"date":432,"type":420},"2027-04",{"name":5,"class":6},32]