[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100538513":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":19,"centralContacts":20,"locations":26,"responsibleParty":43,"collaborators":19,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":19,"eligibilityCriteria":52,"healthyVolunteers":49,"sex":53,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":19,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":19,"overallStatus":29,"whyStopped":19,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"University of Illinois at Chicago","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Assess the performance of this novel eyelid closure device in vivo","The primary goal of this study is to determine the feasibility and success of a temporary magnetic system for tarsorrhaphy (MST) to provide adequate closure of the eyes for ultimate use in conditions causing lagophthalmos (a disorder in eyelid closure). In this disorder, people are unable to sufficiently cover their cornea (the front of the eye), which can lead to dryness, infection, scarring and even blindness. Current therapies are invasive, involving local anesthesia and surgeries, and have a negative cosmetic impact.",[12],"Device: temporary magnetic system for tarsorrhaphy (MST)",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"DEVICE","temporary magnetic system for tarsorrhaphy (MST)","cutting-edge technology has produced smaller magnets with stronger magnetic fields, prompting experts to revisit the use of magnets to facilitate eyelid closure",[9],null,[21],{"name":22,"role":23,"phone":24,"phoneExt":19,"email":25},"Van Ann Tran, MD","CONTACT","312-996-9120","annqtran@uic.edu",[27],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"University of Illinois - Specialty Care Building","RECRUITING","Chicago","Illinois","60612","United States","US",{"type":36,"coordinates":37},"Point",[38,39],-87.65005,41.85003,{"lat":39,"lon":38},[42],{"name":22,"role":23,"phone":24,"phoneExt":19,"email":19},{"type":44,"investigatorFullName":45,"investigatorTitle":46,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"PRINCIPAL_INVESTIGATOR","Van Ann Tran","Principal Investigator","100538513","self-adhering-magnetic-device-to-treat-corneal-exposure-100538513",false,"NCT06291818","Self-Adhering Magnetic Device to Treat Corneal Exposure","Inclusion Criteria:\n\n* Males and females ages 18-80 years old.\n* Patients with recent corneal abrasion and no signs of infection in the examination\n* Patients with lagophthalmos\n* Normal Controls\n\nExclusion Criteria:\n\n* Individuals with adhesive or tape allergies.\n* Individuals with a history of metal pieces\u002Fshavings embedded in the eye (such as from welding or metalworking)\n* Individuals with eye infections","ALL","18 Years","80 Years",{"count":57,"type":58},25,"ESTIMATED","INTERVENTIONAL",[61],"NA","Paralytic lagophthalmos can be difficult to treat and manage. It has a host of causes and effects, one of which (for the latter) is exposure keratopathy. Untreated, this can lead to corneal ulceration, inflammation, and potentially blindness. Despite a variety of attempts at treating this complex condition, none have satisfactorily reduced complications ranging from ease of use to aesthetics. With improvement in magnetic technology, however, that may change. Barmettler et al (2014) have demonstrated preliminary success of externally affixed magnets in closing both model and patient eyelids. As such, we hypothesize that magnetic devices can be used to treat corneal exposure by controlling eyelid position.",[64,65],"Paralytic Lagophthalmos","Corneal Exposure","2026-05-18",{"date":68,"type":69},"2026-05-22","ACTUAL",{"date":71,"type":69},"2024-04-17",{"date":73,"type":58},"2027-09-01",{"name":5,"class":6},1]