[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100611150":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":13,"locations":20,"responsibleParty":39,"collaborators":42,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":47,"sex":52,"minAge":53,"maxAge":7,"enrollmentInfo":54,"targetDuration":7,"studyType":57,"phases":7,"briefSummary":58,"conditions":59,"keywords":64,"overallStatus":22,"whyStopped":7,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"Tata Memorial Centre","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"BEHAVIORAL","Neurological assessment","This assessment will include Speech, Cerebellar function and Quality of Life questionnaires using mobile application.",[14],{"name":15,"role":16,"phone":17,"phoneExt":18,"email":19},"Dr Archya Dasgupta, Radiation Oncology, MD","CONTACT","8097081506","91-22-24177000","archya1010@gmail.com",[21],{"facility":5,"status":22,"city":23,"state":24,"zip":25,"country":26,"countryCode":27,"cosmosGeoPoint":28,"geoPoint":33,"contacts":34},"RECRUITING","Mumbai","Maharashtra","400012","India","IN",{"type":29,"coordinates":30},"Point",[31,32],72.88261,19.07283,{"lat":32,"lon":31},[35,37],{"name":36,"role":16,"phone":17,"phoneExt":7,"email":19},"Dr Archya Dasgupta, MD",{"name":36,"role":38,"phone":7,"phoneExt":7,"email":7},"PRINCIPAL_INVESTIGATOR",{"type":38,"investigatorFullName":40,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Dr Archya Dasgupta","Associate Professor, Radiation Oncology",[43],{"name":44,"class":6},"Bhabha Atomic Research Centre","100611150","self-administered-remote-neurological-examination-using-mobile-application-in-patients-with-brain-tumors-100611150",false,"NCT07236840","Self-administered Remote Neurological Examination Using Mobile Application in Patients With Brain Tumors","NEMO","Inclusion Criteria:\n\n1. Diagnosis of brain tumors (histopathology\u002F radiology).\n2. Age \\> 5 years\n3. Patient or caregiver have access to an android smart phone and is able to install the mobile application.\n4. Expected survival more than 6 months during study accrual.\n5. Signing patient consent or parent consent\u002F child assent form (as appropriate).\n\nExclusion Criteria:\n\n1. Patient or caregiver is not reliable to follow instructions or use the mobile application.\n2. Patient with severe cognitive or psychiatric issues causing difficulty in using the app or follow instructions.\n3. Karnofsky Performance Status (KPS) or Lansky Performance Status LPS) \\\u003C50.\n4. Terminal illness with expected life expectancy (\\\u003C6 months).","ALL","5 Years",{"count":55,"type":56},600,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to evaluate the feasibility and accuracy of a self-administered remote neurological examination using the \"Iskhaa\" mobile application in patients with brain tumors aged above 5 years who are able to follow app-based instructions.\n\nThe main questions it aims to answer are:\n\n1. Development of a mobile application equipped with symptom assessment and recording videos as patients perform specific neurological tasks.\n2. Development and validation of the AI model to detect functional changes and predict subsequent neurological deterioration.\n\nParticipants will:\n\n1. Use the Iskhaa mobile application to perform guided self-neurological examinations following pre-recorded video instructions.\n2. Complete EORTC QLQ-C30 and BN20 questionnaires for quality of life assessment.\n3. Record and upload videos (e.g., speech, walking, limb movements) using their mobile camera for analysis.\n4. In Phase 1 (onsite), 100 participants will use the app under supervision to ensure usability and accuracy.\n5. In Phase 2 (offsite), 500 participants will use the app independently at home for monthly self-assessments, with reminders and follow-up support.\n6. Continue routine clinic visits every 3-6 months and imaging every 6-12 months as per standard clinical care.\n\nThe study will compare app-recorded data with physician assessments to determine agreement and validity of remote neurological monitoring using artificial intelligence analysis.",[60,61,62,63],"CNS Tumor","Artificial Intelligence (AI)","Glioma","Digital Health",[65,66,67],"neurological examination","mobile application","brain tumors","2026-02-21",{"date":70,"type":71},"2026-02-24","ACTUAL",{"date":73,"type":71},"2026-02-20",{"date":75,"type":56},"2027-11-05",{"name":5,"class":6},1]