[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607707":3},{"organization":4,"armGroups":7,"interventions":28,"overallOfficials":40,"centralContacts":44,"locations":54,"responsibleParty":102,"collaborators":104,"id":113,"slug":114,"hasResults":115,"nctId":116,"briefTitle":117,"officialTitle":118,"acronym":119,"eligibilityCriteria":120,"healthyVolunteers":121,"sex":122,"minAge":123,"maxAge":39,"enrollmentInfo":124,"targetDuration":39,"studyType":127,"phases":128,"briefSummary":130,"conditions":131,"keywords":133,"overallStatus":57,"whyStopped":39,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":137,"startDateStruct":140,"completionDateStruct":142,"leadSponsor":144,"locationsCount":145},{"fullName":5,"class":6},"Medical College of Wisconsin","OTHER",[8,14,20,24],{"label":9,"type":10,"description":11,"interventionNames":12},"Self-sampling","EXPERIMENTAL","Participants will self-sample the anal canal with a swab. They will do this at home and at a clinic.",[13],"Other: Nylon-flocked Swab",{"label":15,"type":16,"description":17,"interventionNames":18},"Clinician sampling","ACTIVE_COMPARATOR","A clinician will collect a sample from the anal canal of the participant with a swab. They will do this at the clinic.",[19,13],"Behavioral: Self-sampling",{"label":21,"type":10,"description":22,"interventionNames":23},"Nylon-flocked swab","This is a swab with nylon-flocked material at the tip.",[19],{"label":25,"type":16,"description":26,"interventionNames":27},"Dacron swab","This is a swab with a Dacron tip.",[19,13],[29,35],{"type":30,"name":9,"description":31,"armGroupLabels":32,"otherNames":33},"BEHAVIORAL","Self-sampling instructions will be provided to participants who will insert the swab into the anus to collect cells. Then the participant will put the swab in a vial of transport fluid for assessment at a laboratory.",[15,25,21],[34],"self-collection",{"type":6,"name":36,"description":37,"armGroupLabels":38,"otherNames":39},"Nylon-flocked Swab","At the cytology appointment, participants may receive self-sampling or clinician sampling with 1 of 2 kinds of swabs. The nylon-flocked swab is the intervention and will be assessed on patient acceptability and patient and clinician ability to collect an adequate sample.",[15,25,9],null,[41],{"name":42,"affiliation":5,"role":43},"Alan Nyitray, PhD","PRINCIPAL_INVESTIGATOR",[45,50],{"name":46,"role":47,"phone":48,"phoneExt":39,"email":49},"Alan G Nyitray, PhD","CONTACT","4149557701","anyitray@mcw.edu",{"name":51,"role":47,"phone":52,"phoneExt":39,"email":53},"Jenna Nitkowski, PhD","414-955-2126","jnitkowski@mcw.edu",[55,74,90],{"facility":56,"status":57,"city":58,"state":59,"zip":60,"country":61,"countryCode":62,"cosmosGeoPoint":63,"geoPoint":68,"contacts":69},"University of Chicago","RECRUITING","Chicago","Illinois","60637","United States","US",{"type":64,"coordinates":65},"Point",[66,67],-87.65005,41.85003,{"lat":67,"lon":66},[70],{"name":71,"role":47,"phone":72,"phoneExt":39,"email":73},"Aniruddha Hazra, MD","773-795-2016","ahazra2@bsd.uchicago.edu",{"facility":75,"status":57,"city":76,"state":77,"zip":78,"country":61,"countryCode":62,"cosmosGeoPoint":79,"geoPoint":83,"contacts":84},"The University of Texas M.D. Anderson Cancer Center","Houston","Texas","77030",{"type":64,"coordinates":80},[81,82],-95.36327,29.76328,{"lat":82,"lon":81},[85,88],{"name":86,"role":47,"phone":87,"phoneExt":39,"email":39},"Craig Messick, MD","713-745-1544",{"name":39,"role":47,"phone":39,"phoneExt":39,"email":89},"cmessick@mdanderson.org",{"facility":5,"status":57,"city":91,"state":92,"zip":93,"country":61,"countryCode":62,"cosmosGeoPoint":94,"geoPoint":98,"contacts":99},"Milwaukee","Wisconsin","53226",{"type":64,"coordinates":95},[96,97],-87.90647,43.0389,{"lat":97,"lon":96},[100],{"name":101,"role":47,"phone":48,"phoneExt":39,"email":49},"Alan Nyitray",{"type":43,"investigatorFullName":42,"investigatorTitle":103,"investigatorAffiliation":5,"oldNameTitle":39,"oldOrganization":39},"Associate Professor",[105,108,109,111],{"name":106,"class":107},"National Cancer Institute (NCI)","NIH",{"name":56,"class":6},{"name":110,"class":6},"Froedtert Hospital",{"name":112,"class":6},"M.D. Anderson Cancer Center","100607707","self-sampling-to-optimize-anal-lesion-outcomes-100607707",false,"NCT07192055","Self-sampling to Optimize Anal Lesion Outcomes","Self-sampling to Optimize Anal Lesion Outcomes (SOLO)","SOLO","A potential study subject who meets all of the following inclusion criteria is eligible to participate in the study. Note that these criteria apply regardless of HPV vaccination status or disability status.\n\nInclusion Criteria:\n\n1. Age ≥ 35 years for those who are HIV-positive or ≥ 45 years for those who are HIV-negative.\n2. Must be either:\n\n   1. A cisgender or transgender sexual minority man, or\n   2. A transgender woman who has sex with men.\n3. Resides in Chicago, Houston, or Milwaukee metropolitan area.\n4. Is willing to attend a study clinic.\n5. Speak and understand either English or Spanish\n6. Ability to understand a written informed consent document, and the willingness to sign it.\n\nExclusion Criteria:\n\nA potential study subject who meets any of the following exclusion criteria is ineligible to participate in the study.\n\n1. Was a participant in the PAC Self-Swab Study in Milwaukee.\n2. Currently on anticoagulants, with the exception of aspirin or non-steroidal anti-inflammatory drugs (NSAIDs), e.g., ibuprofen, naproxen.\n3. Diagnosed with hemophilia, cirrhosis with bleeding varices, or thrombocytopenia.\n4. Presence of any contraindicating severe disease or condition, e.g., anal stenosis.\n5. Plans to move within 12 months after enrollment.",true,"ALL","35 Years",{"count":125,"type":126},572,"ESTIMATED","INTERVENTIONAL",[129],"NA","The purpose of this research study is to find ways to increase anal cancer screening among people at increased risk for anal cancer. This study will try to find out if persons will do an intervention (self-sampling of the anal canal) and if it affects cytology and high-resolution anoscopy (HRA) appointment attendance. Secondarily, the study will assess if a person who gets their choice of either self-sampling or healthcare provider sampling affects clinic attendance.",[132],"Anal Cancer",[134,135],"anal cancer","human papillomavirus","2026-05-11",{"date":138,"type":139},"2026-05-12","ACTUAL",{"date":141,"type":139},"2025-11-18",{"date":143,"type":126},"2029-03-31",{"name":5,"class":6},3]