[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100561209":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":33,"centralContacts":37,"locations":48,"responsibleParty":64,"collaborators":42,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":69,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":42,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":89,"overallStatus":93,"whyStopped":42,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Sir Run Run Shaw Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"SED patient","EXPERIMENTAL","SED patients who received semi-elemental exclusive enteral nutrition.",[13],"Dietary Supplement: peptison liquid",{"label":15,"type":16,"description":17,"interventionNames":18},"PD patient","PLACEBO_COMPARATOR","PD patients who received polymeric exclusive enteral nutrition.",[19],"Dietary Supplement: Enteral nutritional suspension",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","peptison liquid","CD patients requiring bowel resection and preoperative EEN were randomized to receive peptison liquid for 6 weeks.",[9],[27],"Nutricia, Amsterdam, Netherlands",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Enteral nutritional suspension","CD patients requiring bowel resection and preoperative EEN were randomized to receive enteral nutritional suspension for 6 weeks.",[15],[27],[34],{"name":35,"affiliation":5,"role":36},"Xiujun Cai","STUDY_CHAIR",[38,44],{"name":39,"role":40,"phone":41,"phoneExt":42,"email":43},"Wei Zhou","CONTACT","+8613588706479",null,"zhouweisrrs@zju.edu.cn",{"name":45,"role":40,"phone":46,"phoneExt":42,"email":47},"Xiaolong Ge","+8613867106984","gxlmed@zju.edu.cn",[49],{"facility":39,"status":42,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Hangzhou","Zhejiang","310016","China","CN",{"type":56,"coordinates":57},"Point",[58,59],120.16142,30.29365,{"lat":59,"lon":58},[62],{"name":45,"role":40,"phone":63,"phoneExt":42,"email":47},"+86-13867106984",{"type":65,"investigatorFullName":39,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":42,"oldOrganization":42},"SPONSOR_INVESTIGATOR","Clinical Professor","100561209","semi-elemental-versus-polymeric-een-in-the-preoperative-optimization-for-patients-with-cd-100561209",false,"NCT06587178","Semi-elemental Versus Polymeric EEN in the Preoperative Optimization for Patients with CD","Semi-elemental Versus Polymeric Exclusive Enteral Nutrition in the Preoperative Optimization for Patients with Crohn's Disease: a Randomized Controlled Trial","SEPEN-CD","Inclusion Criteria:\n\n1. elective bowel resection for Crohn's disease;\n2. preoperative diagnosis of Crohn's disease;\n3. age between 18 to 65 years old;\n4. malnutrition;\n5. the Crohn's disease activity index over 150;\n6. nasal feeding.\n\nExclusion Criteria:\n\n1. emergency surgery;\n2. preoperative exclusive enteral nutrition before three months;\n3. can not tolerate enteral nutrition;\n4. less than 6 weeks of exclusive enteral nutrition;\n5. preoperative corticosteroids within 3 months;\n6. history of gastrointestinal surgery;\n7. isolated colon disease;\n8. metabolic disease (diabetes, hyperthyroidism).","ALL","18 Years","65 Years",{"count":79,"type":80},304,"ESTIMATED","INTERVENTIONAL",[83],"NA","Growing evidence has shown that exclusive enteral nutrition (EEN) plays an important role in the preoperative optimization for patients with Crohn's disease (CD). However, the efficacy and safety of different types of enteral feeds including semi-elemental and polymeric enteral nutrition on CD have not been investigated. The aim of this study was to compare the role of semi-elemental and polymeric enteral nutrition on CD.",[86,87,88],"Crohn Disease","Nutrition Disorders","Surgery",[90,91,92],"Crohn's disease","Exclusive enteral nutrition","surgery","NOT_YET_RECRUITING","2024-09-05",{"date":96,"type":97},"2024-09-19","ACTUAL",{"date":99,"type":80},"2024-10-01",{"date":101,"type":80},"2025-12-30",{"name":39,"class":6},1]