[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643048":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":33,"centralContacts":39,"locations":49,"responsibleParty":69,"collaborators":43,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":43,"eligibilityCriteria":78,"healthyVolunteers":74,"sex":79,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":43,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":92,"overallStatus":52,"whyStopped":43,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"The University of Texas Health Science Center at San Antonio","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"STN-DBS Group","EXPERIMENTAL","Participants diagnosed with Parkinson's Disease who have subthalamic nucleus (STN) deep brain stimulation as a primary target for their condition",[13,14],"Device: Polysomnography ON stimulation then OFF","Device: Polysomnography OFF stimulation then ON",{"label":16,"type":10,"description":17,"interventionNames":18},"GPi-DBS Group","Participants diagnosed with Parkinson's Disease who have Globus Pallidus internus (GPi) deep brain stimulation as a primary target for their condition.",[13,14],[20,27],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Polysomnography ON stimulation then OFF","Patients will undergo a 2-night Polysomnography (PSG). Stimulation will be set to \"ON\" stimulation for the 1st PSG night, then will cross over the 2nd PSG study night in the opposite stimulation state. Each subject will act as their own control.",[16,9],[26],"PSG ON\u002FOFF",{"type":21,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"Polysomnography OFF stimulation then ON","Patients will undergo a 2-night Polysomnography (PSG). Stimulation will be set to \"OFF\" stimulation for the 1st PSG night, then will cross over the 2nd PSG study night in the opposite stimulation state. Each subject will act as their own control.",[16,9],[32],"PSG OFF\u002FON",[34,37],{"name":35,"affiliation":5,"role":36},"Eleni O Vaou, MD","PRINCIPAL_INVESTIGATOR",{"name":38,"affiliation":5,"role":36},"Pablo Coss, MD",[40,45],{"name":35,"role":41,"phone":42,"phoneExt":43,"email":44},"CONTACT","210 450 8048",null,"vaou@uthscsa.edu",{"name":46,"role":41,"phone":47,"phoneExt":43,"email":48},"Omalys Biggs Rodriguez","210-450-7547","biggsrodrigu@uthscsa.edu",[50],{"facility":51,"status":52,"city":53,"state":54,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"The University of Texas Health Science Center at San Antonio - Brain Health Center","RECRUITING","San Antonio","Texas","78229","United States","US",{"type":59,"coordinates":60},"Point",[61,62],-98.49363,29.42412,{"lat":62,"lon":61},[65,67],{"name":46,"role":41,"phone":66,"phoneExt":43,"email":48},"210-450-8456",{"name":35,"role":41,"phone":68,"phoneExt":43,"email":44},"210-450 8048",{"type":36,"investigatorFullName":70,"investigatorTitle":71,"investigatorAffiliation":5,"oldNameTitle":43,"oldOrganization":43},"Eleni Vaou","Associate Professor","100643048","sensing-in-sleep-deep-brain-stimulation-100643048",false,"NCT07636720","Sensing in Sleep Deep Brain Stimulation","Sensing in Sleep and Deep Brain Stimulation","Inclusion Criteria:\n\n1. Ability of subject to understand and the willingness to sign a written informed consent document.\n2. Males and females; Age 40-80\n3. Subjects with the diagnosis of idiopathic PD consistent with the United Kingdom Parkinson Disease society brain bank criteria, or documented diagnosis of Parkinson Disease who have a Deep Brain Implant, Percept RC device to subthalamic nucleus (STN) or Globus pallidus internus (GPi).\n4. Willingness to adhere to the PSG regimen and turn DBS off for one night.\n5. A score of ≥23 on the Montreal Cognitive Assessment (MoCA)\n6. Be willing to stop any sleep hypnotics such as benzodiazepines and Ambien, with a 3 day washout period.\n\nExclusion Criteria:\n\n1. History of severe cardiovascular disease, untreated obstructive sleep apnea (OSA).\n2. History of other neurological disorders affecting the central nervous system such as stroke, multiple sclerosis, tumors, amyotrophic lateral sclerosis or muscle disease such as muscular dystrophy, myopathy.\n3. History of Dementia.\n4. Report dopaminergic medication changes in the past month.","ALL","40 Years","80 Years",{"count":83,"type":84},20,"ESTIMATED","INTERVENTIONAL",[87],"NA","Participants in this study have Parkinson's Disease and already have a device, called the Percept RC Deep Brain Stimulation device implanted. People with Parkinson's disease often have issues related to sleep such as bad quality of sleep, waking up often and sleep apnea (breathing stops and starts during sleep).\n\nFor this study, participants will be sleeping overnight in the study sleep lab for two nights. One night, Deep Brain Stimulation (DBS) device turned on and one night with the DBS off, either in this order or the reverse.",[90,91],"Parkinson's Disease and Parkinsonism","Dyssomnia",[93,94,95],"Deep Brain Stimulation","Polysomnography","Sleep Disorders","2026-06-03",{"date":98,"type":99},"2026-06-09","ACTUAL",{"date":101,"type":99},"2026-02-27",{"date":103,"type":84},"2028-02-01",{"name":5,"class":6},1]