[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100619139":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":54,"collaborators":26,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":63,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":26,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":80,"overallStatus":88,"whyStopped":26,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Centre Hospitalier St Anne","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Stroke patients in the early subacute phase","EXPERIMENTAL","Patients will be followed for 6 months over three visits. They will undergo validated sensory, motor, and cognitive clinical assessments, as well as MRI scans and manual dexterity tests performed with and without the addition of vibratory stimulation to the fingers, using a tool previously developed as part of this project.",[13,14],"Device: Haptic stimulation device","Other: Brain MRI",{"label":16,"type":17,"description":18,"interventionNames":19},"Healthy controls matched in age, sex and laterality with stroke patients","ACTIVE_COMPARATOR","Healthy control participants will be assessed during a single visit. They will undergo motor, sensory, and cognitive clinical assessments, as well as manual dexterity tasks performed with and without the addition of finger vibrations using a previously developed tool. They will also undergo anatomical, resting-state functional, and diffusion brain MRI sequences. Each healthy participant will be matched to a patient in terms of age, sex, and handedness of the affected limb. For example, if we include a 60-year-old male post-stroke patient who is right-handed and has a right upper-limb impairment, we will include a healthy male participant aged 60 ± 5 years who is also right-handed.",[13,14],[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Haptic stimulation device","Both patients and healthy participants will perform manual dexterity tasks using the Dextrain Manipulandum. In addition, they will receive finger vibrations delivered via rings that we have previously developed. These vibrations will have a frequency of 150 Hz and will be delivered for a duration of 150 ms.",[16,9],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Brain MRI","Subjects and patients will undergo anatomical, resting-state functional, and diffusion brain MRI sequences.",[16,9],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Pavel Lindberg","CONTACT","+33140789244","pavel.lindberg@inserm.fr",[38],{"facility":39,"status":26,"city":40,"state":26,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"GHU Psychiatrie et Neurosciences","Paris","75014","France","FR",{"type":45,"coordinates":46},"Point",[47,48],2.3488,48.85341,{"lat":48,"lon":47},[51],{"name":52,"role":34,"phone":26,"phoneExt":26,"email":53},"Sabrina Lekcir","sabrina.lekcir@ghu-paris.fr",{"type":55,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100619139","sensory-mechanisms-of-manual-dexterity-recovery-after-stroke-a-prospective-cohort-study-of-prediction-and-cerebral-correlates-100619139",false,"NCT07340736","Sensory Mechanisms of Manual Dexterity Recovery After Stroke: a Prospective Cohort Study of Prediction and Cerebral Correlates","HapticS 2","Inclusion Criteria:\n\n* First symptomatic stroke, ischaemic or haemorrhagic in the early subacute phase (up to 3 weeks post-stroke)\n* Upper limb paresis (≤4\u002F5 MRC Scale)\n* Ability to grasp, lift and put down 1 block (from the BBT test)\n* Be affiliated to a social security\n\nExclusion Criteria:\n\n* Presence of another neurological or musculoskeletal condition affecting upper limb movement\n* Severe cognitive impairment and\u002For aphasia with inability to understand and carry out instructions\n* Contraindications to MRI (claustrophobia, presence of cochlear implants and\u002For pacemakers)\n* Persons subject to legal protection measures\n* Persons subject to judicial protection measures\n* Pregnancy\n* Life-threatening conditions or conditions requiring follow-up at 6 months\n* Epilepsy\n* Known hypersensitivity or allergy to silicone",true,"ALL","18 Years","85 Years",{"count":68,"type":69},90,"ESTIMATED","INTERVENTIONAL",[72],"NA","In the proposed research, we will assess motor and sensory functions of the hand using clinical tests and a tool designed to measure manual dexterity combined with vibrotactile stimulation. We will also evaluate the integrity of brain structure and function using MRI.",[75,76,77,78,79],"Stroke","Upper Extremity Paresis","Manual Dexterity","Sensory Integration Dysfunction","Vibration",[81,82,83,84,85,86,87],"stroke","haptic","vibration","sensorimotor impairment","manual dexterity","prediction of recovery","MRI","NOT_YET_RECRUITING","2026-01-05",{"date":91,"type":92},"2026-01-14","ACTUAL",{"date":94,"type":69},"2026-03-01",{"date":96,"type":69},"2028-03-01",{"name":5,"class":6},1]