[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100615622":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":26,"centralContacts":31,"locations":40,"responsibleParty":59,"collaborators":21,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":64,"sex":70,"minAge":71,"maxAge":21,"enrollmentInfo":72,"targetDuration":21,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":84,"whyStopped":21,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Region Stockholm","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"ICG-guided lymphadenectomy +\u002F- LECS","EXPERIMENTAL","Laparoscopic and endoscopic cooperative surgery to locally resect the gastric scar. This method will we be used for cases where pathology showed positive vertical margin after ESD. Otherwise, submucosal injection of ICG in quadrants around the scar after ESD, followed by laparoscopic resection of positive lymph nodes after 15 minutes",[13,14],"Procedure: ICG-guided lymphadenectomy","Procedure: Laparoscopic and endoscopic cooperative surgery (LECS)",[16,22],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"PROCEDURE","ICG-guided lymphadenectomy","Submucosal injection of ICG in quadrants around the scar after ESD, followed by laparoscopic resection of positive lymph nodes after 15 minutes",[9],null,{"type":17,"name":23,"description":24,"armGroupLabels":25,"otherNames":21},"Laparoscopic and endoscopic cooperative surgery (LECS)","Endoscopic marking and submucosal cutting around the scar after ESD, followed by perforation of the gastric wall and laparoscopic full thickness resection of the area under endoscopic guidance.",[9],[27],{"name":28,"affiliation":29,"role":30},"Ioannis Rouvelas, MD, PhD","ME Övre buk, Karolinska Universitetssjukhuset","PRINCIPAL_INVESTIGATOR",[32,36],{"name":28,"role":33,"phone":34,"phoneExt":21,"email":35},"CONTACT","+46707976814","ioannis.rouvelas@ki.se",{"name":37,"role":33,"phone":38,"phoneExt":21,"email":39},"Henrik Maltzman, MD","+46706334445","henrik.maltzman@ki.se",[41],{"facility":42,"status":21,"city":43,"state":21,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Karolinska University Hospital Huddinge","Stockholm","141 57","Sweden","SE",{"type":48,"coordinates":49},"Point",[50,51],18.06871,59.32938,{"lat":51,"lon":50},[54,57],{"name":55,"role":33,"phone":34,"phoneExt":21,"email":56},"Ioannis Rouvelas, MD PhD","ioannis.rouvelas@regionstockholm.se",{"name":37,"role":33,"phone":38,"phoneExt":21,"email":58},"henrik.maltzman@regionstockholm.se",{"type":30,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":21,"oldOrganization":21},"Ioannis Rouvelas","Principal Investigator, MD, PhD","100615622","sentinel-node-resection-with-or-without-lecs-after-noncurative-esd-for-egc-100615622",false,"NCT07295002","Sentinel Node Resection With or Without LECS After Noncurative ESD for EGC","COmpletion Sentinel Node Resection With or Without Minimally invAsive and Endoscopic Cooperative Surgery Following noncuRative Endoscopic Submucosal Dissection for Early Gastric Cancer","Co-SNARE","Inclusion Criteria:\n\n* EGC previously treated with ESD according to current guidelines (differentiated adenocarcinoma, not ulcerative, of any size, differentiated adenocarcinoma ulcerative \\\u003C\u002F=3cm, undifferentiated adenocarcinoma not ulcerative \\\u003C\u002F=2cm)\n* Non curative resection\n\n  * Lymphovascular invasion\n  * Non-radical resection vertical margin\n  * deep submucosal invasion\n* Signed informed consent\n\nExclusion Criteria:\n\n* Location within 2 cm from cardia or pylorus\n* Non-curative resection with only non-radicality horizontal margin\n* Inoperative because of severe comorbidities\n* Previous radiotherapy to the upper abdomen\n* Pregnancy\n* Allergy to ICG\n* Inability to provide informed consent due to cognitive impairment, language barrier, or other reasons impairing understanding and autonomous decision-making.","ALL","18 Years",{"count":73,"type":74},10,"ESTIMATED","INTERVENTIONAL",[77],"NA","For patients with non-curative resection after endoscopic submucosal dissection (ESD) for early gastric cancer (EGC), complementary surgery is generally recommended. However, about 2\u002F3 of patients have no remaining tumor in the stomach or regional lymph nodes. In this trial, Indocyanine Green (ICG)-guided lymphadenectomy with or without laparoscopic and endoscopic cooperative surgery (LECS) will be tested as a less invasive alternative in such cases. For patients with a primary radically resected EGC, ICG-guided lymphadenectomy alone will be performed. For patients with deep-margin positive EGC, ICG-guided lymphadenectomy and LECS will be performed, in order to ensure both local tumor control in the stomach and in regional nodes.",[80],"Early Gastric Cancer",[82,83],"sentinel node-resection","minimal invasive surgery","NOT_YET_RECRUITING","2025-12-15",{"date":87,"type":88},"2025-12-19","ACTUAL",{"date":90,"type":74},"2026-01-01",{"date":92,"type":74},"2029-10-01",{"name":5,"class":6},1]