[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100599062":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":33,"locations":43,"responsibleParty":70,"collaborators":74,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":10,"eligibilityCriteria":84,"healthyVolunteers":80,"sex":85,"minAge":86,"maxAge":10,"enrollmentInfo":87,"targetDuration":90,"studyType":91,"phases":10,"briefSummary":92,"conditions":93,"keywords":95,"overallStatus":46,"whyStopped":10,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Jimma University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A",null,"This is a group of patients with the diagnosis of sepsis of any focus but without any signs\u002Fsymptoms suggestive of cardiac involvement.",[13],"Other: Standard treatment for sepsis of any focus",{"label":15,"type":10,"description":16,"interventionNames":17},"Group B","This is a cohort of patients with the diagnosis of sepsis of any foci and with the evidences of cardiac involvement defined as one or a combination of the following:\n\n* Clinical symptoms include chest pain, dyspnea, or arrhythmias.\n* Abnormal biomarkers, including troponins or BNP levels.\n* Evidence of cardiac dysfunction on ECG or echocardiography.\n\nBoth groups will be followed prospectively for 9 to 1 year to evaluate their outcomes.",[18],"Other: Treatment for the sepsis with standard management of cardiac failure",[20,24],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"Standard treatment for sepsis of any focus","This group of patients will be treated for the sepsis of any focus as per standard.",[9],{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":10},"Treatment for the sepsis with standard management of cardiac failure","This group of patients will be treated for the sepsis and management of cardiac failure with additional supportive care cocktails based on the specific indication.",[15],[29],{"name":30,"affiliation":31,"role":32},"Nikolaus Alexander Haas, MD, Pediatician, Cardiologist","Ludwig Maximillians University of Munich, Germany","STUDY_CHAIR",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":10,"email":38},"Kedir Negesso Tukeni, MD, Internist, Cardiologist","CONTACT","0913521475","Kedir.negesso@ju.edu.et",{"name":40,"role":36,"phone":41,"phoneExt":10,"email":42},"Kidus Tesfaye Bezabih, MD, Internist","0920197780","kdstesfaye@gmail.com",[44],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Jimma University Hospital","RECRUITING","Jimma","Oromiya","378","Ethiopia","ET",{"type":53,"coordinates":54},"Point",[55,56],36.83441,7.67344,{"lat":56,"lon":55},[59,61,63,66,68],{"name":60,"role":36,"phone":37,"phoneExt":10,"email":38},"Kedir N Tukeni, MD, Internist, cardiologist",{"name":62,"role":36,"phone":41,"phoneExt":10,"email":42},"Kidus T Bezabih, MD, Internist",{"name":64,"role":65,"phone":10,"phoneExt":10,"email":10},"Elsah T Asefa, MD, cardiologist","SUB_INVESTIGATOR",{"name":67,"role":65,"phone":10,"phoneExt":10,"email":10},"Mohammed M Abafogi, MD, cardiologist",{"name":69,"role":65,"phone":10,"phoneExt":10,"email":10},"Esayas K Gudina, MD, Internist",{"type":71,"investigatorFullName":72,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Kedir Negesso Tukeni","MD, Internist and cardiologist, PhD fellow in Medical Research, Cardiovascular Science",[75],{"name":76,"class":77},"Ethiopian Society of Cardiac Professionals","UNKNOWN","100599062","sepsis-and-myocarditis-100599062",false,"NCT07079605","Sepsis and Myocarditis","Cardiac Manifestations of Sepsis and Its Association With Disease Outcome: A Prospective Cohort Study","Inclusion Criteria:\n\n* All adult patients aged 18 years and above diagnosed with sepsis admitted to Jimma University Medical Center during the study periods that are willing to participate and continue follow-up of their disease condition for at least one year.\n\nExclusion Criteria:\n\n* Patients with any kind of pre-existing established cardiac disease prior to their sepsis diagnosis and those who are not willing to participate or not willing to have follow-up of their disease condition for at least one year.","ALL","18 Years",{"count":88,"type":89},226,"ESTIMATED","9 Months","OBSERVATIONAL","This prospective cohort study aims to investigate the cardiac manifestations of sepsis and their influence on disease outcomes among adult patients at Jimma University Medical Center, Ethiopia, from May 2025 to May 2026. The research will include adults aged 18 and older with sepsis, categorizing them based on the presence or absence of cardiac involvement, which will be assessed through clinical symptoms, biomarkers, ECG, and echocardiographic findings. The study will evaluate the persistence of cardiac abnormalities, functional capacity, and survival over one year, utilizing structured data collection and advanced statistical methods, including survival analysis and regression techniques, to identify predictors of adverse outcomes.",[94],"Sepsis-related Myocarditis",[96,97,98,99,100,50],"Sepsis","myocarditis","mortality","survival analysis","low in-come countries","2025-07-14",{"date":103,"type":104},"2025-07-23","ACTUAL",{"date":106,"type":104},"2025-05-09",{"date":108,"type":89},"2026-09-22",{"name":5,"class":6},1]