[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100601920":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":16,"locations":25,"responsibleParty":74,"collaborators":76,"id":82,"slug":83,"hasResults":84,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":84,"sex":90,"minAge":91,"maxAge":10,"enrollmentInfo":92,"targetDuration":10,"studyType":95,"phases":10,"briefSummary":96,"conditions":97,"keywords":98,"overallStatus":28,"whyStopped":10,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"Children's Hospital Medical Center, Cincinnati","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Sickle Cell Anemia",null,"Those with sickle cell anemia (SCA).",[13],{"name":14,"affiliation":5,"role":15},"Russell E Ware, MD, PhD","PRINCIPAL_INVESTIGATOR",[17,22],{"name":18,"role":19,"phone":20,"phoneExt":10,"email":21},"Teresa Latham, DrPh","CONTACT","513-803-7822","Teresa.Latham@cchmc.org",{"name":14,"role":19,"phone":23,"phoneExt":10,"email":24},"513-803-4597","Russell.Ware@cchmc.org",[26,44,58],{"facility":27,"status":28,"city":29,"state":10,"zip":10,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"Centro de Obstetricia y Ginecologia","RECRUITING","Santo Domingo","Dominican Republic","DO",{"type":33,"coordinates":34},"Point",[35,36],-69.89232,18.47186,{"lat":36,"lon":35},[39,42],{"name":40,"role":19,"phone":41,"phoneExt":10,"email":21},"Teresa Latham, PhD","513-803-7922",{"name":43,"role":15,"phone":10,"phoneExt":10,"email":10},"Rafael Mena, PhD",{"facility":45,"status":28,"city":46,"state":10,"zip":10,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":53,"contacts":54},"Caribbean Institute for Health Research, University of West Indies","Kingston","Jamaica","JM",{"type":33,"coordinates":50},[51,52],-76.79358,17.99702,{"lat":52,"lon":51},[55,56],{"name":40,"role":19,"phone":41,"phoneExt":10,"email":21},{"name":57,"role":15,"phone":10,"phoneExt":10,"email":10},"Marvin Reid, MB, BS, PhD",{"facility":59,"status":28,"city":60,"state":10,"zip":10,"country":61,"countryCode":10,"cosmosGeoPoint":62,"geoPoint":66,"contacts":67},"Buganda Medical Centre","Mwanza","Tanzania",{"type":33,"coordinates":63},[64,65],32.9,-2.51667,{"lat":65,"lon":64},[68,71],{"name":69,"role":19,"phone":10,"phoneExt":10,"email":70},"Emmanuela Ambrose MD","emmanuelaambrose@gmail.com",{"name":40,"role":19,"phone":72,"phoneExt":10,"email":73},"1-513-803-7922","teresa.latham@cchmc.org",{"type":75,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[77,79],{"name":78,"class":6},"The University of The West Indies",{"name":80,"class":81},"Centro de Obstetricia y Ginecologia Recruiting Santo Domingo, Dominican Republic","UNKNOWN","100601920","serial-assessment-of-fertility-experiences-100601920",false,"NCT07116772","Serial Assessment of Fertility Experiences","A Prospective Longitudinal Study of Growth, Development, Fertility and Reproductive Outcomes Among Adolescents and Young Adults With Sickle Cell Anemia With Hydroxyurea","SAFE","Inclusion Criteria:\n\n* Patients with documented sickle cell anemia (SCA).\n* At least 8 years of age at the time of enrollment.\n* Enrolled on the EXTEND or SACRED study.\n* Provide informed consent.\n* Able to take part in all parts of the study, including treatments, check-ups, and follow-up visits.\n\nExclusion Criteria:\n\n* Currently taking part in another treatment study (not EXTEND or SACRED).\n* Has received other treatments for sickle cell disease in the past 6 months.","ALL","8 Years",{"count":93,"type":94},250,"ESTIMATED","OBSERVATIONAL","The SAFE study is a long-term research project that watches people with sickle cell anemia (SCA) over time. The main goal is to see how a medicine called hydroxyurea affects their growth, puberty, and ability to have children. A second goal is to see how hydroxyurea affects pregnancy outcomes, by comparing people who take the medicine to those who don't.",[9],[99,100,101],"Hydroxyurea","Fertility","Sickle Cell Disease","2026-02-03",{"date":104,"type":105},"2026-02-04","ACTUAL",{"date":107,"type":105},"2023-07-10",{"date":109,"type":94},"2035-12-31",{"name":5,"class":6},3]