[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100580876":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":42,"responsibleParty":64,"collaborators":26,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":70,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":26,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":26,"overallStatus":45,"whyStopped":26,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Jinling Hospital, China","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"CCTA-based follow-up management group","ACTIVE_COMPARATOR","The subjects will undergo routine clinical and laboratory examinations, as well as follow-up CCTA examinations to assess the progression of plaques and to recommend appropriate management, treatment, and follow-up based on the findings",[13],"Diagnostic Test: Coronary Computed Tomography Angiography",{"label":15,"type":16,"description":17,"interventionNames":18},"clinical-based follow-up management group","SHAM_COMPARATOR","The subjects will undergo routine clinical and laboratory examinations, and recommendations for appropriate management, treatment, and follow-up will be made based on the results.",[19],"Other: Current clinical guidelines",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIAGNOSTIC_TEST","Coronary Computed Tomography Angiography","Based on the assessment of plaque progression after follow-up CCTA examination, patients will be given either intensive treatment or routine treatment.",[9],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Current clinical guidelines","Patients will be treated according to the 2024 ESC Guidelines for the Management of Chronic Coronary Syndromes.",[15],[32],{"name":33,"affiliation":34,"role":35},"Trail Manager","Jinling Hospital,Nanjing University School of Medicine,Nanjing,China","STUDY_CHAIR",[37],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"Longjiang Zhang, MD","CONTACT","13405833167","kevinzhlj@163.com",[43],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Research Institute Of Medical Imaging Jinling Hospital","RECRUITING","Nanjing","Jiangsu","210018","China","CN",{"type":52,"coordinates":53},"Point",[54,55],118.77778,32.06167,{"lat":55,"lon":54},[58,60],{"name":38,"role":39,"phone":59,"phoneExt":26,"email":41},"13405833176",{"name":61,"role":39,"phone":62,"phoneExt":26,"email":63},"Chao Li, MD","18822060230","lclive123123@163.com",{"type":65,"investigatorFullName":66,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","Zhang longjiang,MD","Principal Investigator : Zhang longjiang","100580876","serial-coronary-cta-based-plaque-progression-detection-for-management-of-coronary-heart-disease-100580876",false,"NCT06843005","Serial Coronary CTA-based Plaque Progression Detection for Management of Coronary Heart Disease","Serial Coronary CTA-based Plaque Progression Detection for Management of Coronary Heart Disease: a Randomised Controlled Trial","SUCCESS","Inclusion Criteria:\n\n1. Age between 18 and 80 years old;\n2. Known patients with non-obstructive coronary artery disease (disease duration ≥2 years);\n3. Patients who agree to undergo follow-up CCTA examinations and cooperate in completing follow-up observations.\n\nExclusion Criteria:\n\n1. Patients who have experienced ACS or PCI\u002FCABG;\n2. Patients who have experienced adverse cardiovascular and cerebrovascular events;\n3. Patients who have undergone follow-up CCTA or DSA examinations before enrollment;\n4. Patients with severe hepatic and renal dysfunction;\n5. Patients with contraindications to CCTA examinations;\n6. Patients with poor initial CCTA image quality or data loss.","ALL","18 Years","80 Years",{"count":80,"type":81},3100,"ESTIMATED","INTERVENTIONAL",[84],"NA","The primary objective of this study is to evaluate whether a management strategy based on coronary computed tomography angiography (CCTA) for patients with non-obstructive coronary artery disease can improve the LDL-C target achievement rate compared to a traditional management strategy without follow-up CCTA, thereby reducing the incidence of major adverse cardiovascular and cerebrovascular events over a 3 years period, including all-cause mortality, myocardial infarction, ischemia driven revascularation and stroke.",[87,88,89,90],"Major Adverse Cardiovascular Events (MACE)","Prevention","Coronary Artery Disease(CAD)","CT Angiography","2026-03-19",{"date":93,"type":94},"2026-03-24","ACTUAL",{"date":96,"type":94},"2025-02-28",{"date":98,"type":81},"2028-12-30",{"name":66,"class":6},1]