[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639105":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":40,"responsibleParty":56,"collaborators":26,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":26,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":26,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":43,"whyStopped":26,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Serratus Posterior Superior Intercostal Plane Block Group","EXPERIMENTAL","Participants in this group will receive an ultrasound-guided serratus posterior superior intercostal plane (SPSIP) block prior to surgery using 30 mL of 0.25% bupivacaine, in addition to standard general anesthesia and multimodal analgesia.",[13],"Procedure: SPSIP Block With Bupivacaine",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo Group","PLACEBO_COMPARATOR","Participants in this group will receive an ultrasound-guided placebo block using 30 mL of normal saline under identical conditions, in addition to standard general anesthesia and multimodal analgesia.",[19],"Procedure: SPSIP Block With Saline",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","SPSIP Block With Bupivacaine","Participants will receive an ultrasound-guided SPSIP block using bupivacaine.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"SPSIP Block With Saline","Participants will receive an ultrasound-guided SPSIP block using normal saline under identical conditions.",[15],[32],{"name":33,"affiliation":5,"role":34},"Fatma Acil, M.D.","PRINCIPAL_INVESTIGATOR",[36],{"name":33,"role":37,"phone":38,"phoneExt":26,"email":39},"CONTACT","+905337225225","acilfatma@gmail.com",[41],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":26,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Fatma Acil","RECRUITING","Diyarbakır","Outside of the US","21070","Turkey (Türkiye)",{"type":49,"coordinates":50},"Point",[51,52],40.21721,37.91363,{"lat":52,"lon":51},[55],{"name":33,"role":37,"phone":38,"phoneExt":26,"email":39},{"type":34,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Fatma Acil,MD","Principal Investigator","100639105","serratus-posterior-superior-intercostal-plane-block-for-postoperative-analgesia-in-mastectomy-100639105",false,"NCT07579650","Serratus Posterior Superior Intercostal Plane Block for Postoperative Analgesia in Mastectomy","Mastectomy and Axillary Dissection: Evaluation of the Effect of Serratus Posterior Superior Intercostal Plane Block on Postoperative Analgesia: A Multicenter, Randomized, Placebo-Controlled Trial","Inclusion Criteria:\n\n* Female patients aged 18-65 years\n* ASA physical status I-III\n* Scheduled for elective unilateral mastectomy with axillary lymph node dissection under general anesthesia\n* Able to understand and use the Numeric Rating Scale (NRS) for pain assessment\n* Provided written informed consent\n\nExclusion Criteria:\n\n* Known allergy or hypersensitivity to local anesthetics (e.g., bupivacaine)\n* Coagulopathy, thrombocytopenia (\\\u003C100,000\u002Fmm³), or ongoing anticoagulant\u002Fantiplatelet therapy that cannot be discontinued\n* Infection or skin lesion at the injection site\n* Planned bilateral surgery or additional major surgical procedures\n* Chronic pain conditions or regular use of opioids, gabapentinoids, or centrally acting analgesics\n* Neurological or psychiatric conditions interfering with pain assessment\n* History of previous major thoracic or chest wall surgery on the same side\n* Pregnancy or breastfeeding\n* Refusal to participate or inability to provide informed consent","FEMALE","18 Years","65 Years",{"count":70,"type":71},50,"ESTIMATED","INTERVENTIONAL",[74],"NA","This study aims to evaluate the effect of serratus posterior superior intercostal plane (SPSIP) block on postoperative pain, opioid consumption, and analgesic requirements in patients undergoing mastectomy and axillary lymph node dissection",[77],"Breast Cancer",[79],"mastectomy","2026-05-16",{"date":82,"type":83},"2026-05-19","ACTUAL",{"date":80,"type":83},{"date":86,"type":71},"2026-06-30",{"name":5,"class":6},1]