[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100605604":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":42,"centralContacts":47,"locations":53,"responsibleParty":68,"collaborators":51,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":51,"eligibilityCriteria":77,"healthyVolunteers":73,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":51,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":91,"overallStatus":55,"whyStopped":51,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Ondokuz Mayıs University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Group SPSIP","ACTIVE_COMPARATOR","A bilaterally Serratus Posterior Superior Plane Block (60 ml, %0.25 bupivacaine, totally) + IV morphine patient-controlled analgesia (PCA)",[13,14],"Procedure: Bilateral ultrasound guided Serratus Posterior Superior Plane Block","Drug: IV morphine patient-controlled analgesia",{"label":16,"type":17,"description":18,"interventionNames":19},"Group Control","SHAM_COMPARATOR","A bilaterally Sham block + IV morphine patient-controlled analgesia (PCA)",[14,20],"Procedure: Bilateral ultrasound guided Sham Block",[22,29,36],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"PROCEDURE","Bilateral ultrasound guided Serratus Posterior Superior Plane Block","Bilateral ultrasound-guided Serratus Posterior Superior Plane Block (total of 60 ml, %0.25 bupivacaine) will be performed Multimodal analgesia : Intraoperatively, all patients will receive 0.05 mg\u002Fkg (IBW) iv morphine. Thirty minutes before the end of surgery, 1 gram of intravenous paracetamol will be administered. Postoperative analgesia: iv paracetamol 1gr every 8 hours and IV PCA of 0,5mg\u002Fml morphine. In cases where rescue analgesia is required (NRS score ≥4),iv fentanyl 25-50 mcg and\u002For ibuprofen and\u002For ketamine 10 mg will be administered. Patients are routinely administered iv dexamethasone 4 mg and IV 8 mg ondansetron 20 minutes before end of surgery for postoperative nausea and vomiting prophylaxis.",[9],[28],"Serratus Posterior Superior Plane Block",{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"DRUG","IV morphine patient-controlled analgesia","IV PCA of 0,5mg\u002Fml morphine (the bolus dose is 20 μg\u002Fkg, the lock-in time of 6-10 minutes, the 4-hour limit is adjusted to be 80% of the calculated total amount).",[16,9],[35],"morphine PCA",{"type":23,"name":37,"description":38,"armGroupLabels":39,"otherNames":40},"Bilateral ultrasound guided Sham Block","Bilateral ultrasound-guided needle placement will be performed in the same anatomical plane as in the SPSIP group, but instead of local anesthetic, an equivalent volume of normal saline (30 mL per side) will be injected.\n\nMultimodal analgesia : Intraoperatively, all patients will receive 0.05 mg\u002Fkg (IBW) iv morphine. Thirty minutes before the end of surgery, 1 gram of intravenous paracetamol will be administered. Postoperative analgesia: iv paracetamol 1gr every 8 hours and IV PCA of 0,5mg\u002Fml morphine. In cases where rescue analgesia is required (NRS score ≥4),iv fentanyl 25-50 mcg and\u002For ibuprofen and\u002For ketamine 10 mg will be administered. Patients are routinely administered iv dexamethasone 4 mg and IV 8 mg ondansetron 20 minutes before end of surgery for postoperative nausea and vomiting prophylaxis.",[16],[41],"Sham Block",[43],{"name":44,"affiliation":45,"role":46},"Burhan Dost","Ondokuz Mayis University, Samsun, Atakum 55139","STUDY_DIRECTOR",[48],{"name":44,"role":49,"phone":50,"phoneExt":51,"email":52},"CONTACT","05327042493",null,"burhandost@hotmail.com",[54],{"facility":44,"status":55,"city":56,"state":51,"zip":57,"country":58,"countryCode":51,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"RECRUITING","Samsun","55270","Turkey (Türkiye)",{"type":60,"coordinates":61},"Point",[62,63],36.3361,41.27976,{"lat":63,"lon":62},[66],{"name":67,"role":49,"phone":50,"phoneExt":51,"email":52},"BURHAN DOST",{"type":69,"investigatorFullName":67,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":51,"oldOrganization":51},"PRINCIPAL_INVESTIGATOR","Principal Investigator","100605604","serratus-posterior-superior-plane-block-for-postoperative-pain-in-cardiac-surgery-100605604",false,"NCT07164677","Serratus Posterior Superior Plane Block for Postoperative Pain in Cardiac Surgery","Efficacy of the Serratus Posterior Superior Intercostal Plane Block for Postoperative Acute Pain Management in Open-Heart Surgery","Inclusion Criteria:\n\n* Patients aged 18-80 undergoing elective on-pump open-heart surgery via median sternotomy.\n* American Society of Anesthesiologists (ASA) classification II-III patients.\n* Patients who can use PCA.\n* Patients who will sign the informed consent form.\n\nExclusion Criteria:\n\n* History of opioid use for more than four weeks\n* Chronic pain syndromes\n* Patients with a history of local anesthetic or opioid allergy, hypersensitivity\n* Alcohol and drug addiction\n* Conditions where regional anesthesia is contraindicated\n* Failure in the dermatomal examination performed after the block\n* Emergency surgeries and redo surgeries.\n* Individuals with obstructive sleep apnea.\n* Left ventricular ejection fraction less than 30%.\n* Patients with severe psychiatric illnesses (such as psychosis, dementia) that limit cooperation with verbal numerical pain scales.\n* Pregnant and breastfeeding patients.\n* Hematological disorders.\n* Significant impairment in the function of a major organ (e.g., severe hepatic or renal disease). • Patients who cannot be extubated within the first 6 hours postoperatively.","ALL","18 Years","80 Years",{"count":82,"type":83},50,"ESTIMATED","INTERVENTIONAL",[86],"NA","The aim of this study is to investigate the efficacy of bilateral serratus posterior superior intercostal plane (SPSIP) block on postoperative acute pain and opioid consumption in patients undergoing on-pump open-heart surgery. Postoperative outcomes including pain scores, cumulative morphine use, quality of recovery, and opioid-related side effects will be evaluated within the first 24 hours after surgery.",[89,90],"Cardiac Surgery","Post Operative Pain, Acute",[92,28],"Cardiac surgery","2026-06-30",{"date":95,"type":96},"2026-07-02","ACTUAL",{"date":98,"type":96},"2025-09-13",{"date":100,"type":83},"2027-02-01",{"name":5,"class":6},1]